55 completed, 10 terminated, 2 withdrawn, 1 active not recruiting. 35 Phase 1, 29 Phase 2, 7 Not applicable, 2 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 35 | Completed 29, Terminated 6 |
| Phase 2 | 29 | Completed 24, Terminated 4, Withdrawn 1 |
| Not applicable | 7 | Completed 5, Terminated 1, Withdrawn 1 |
| Phase 3 | 2 | Completed 2 |
Follow Relapsing Chronic Myelogenous Leukemia: new trials by email Literature Review of Relapsing Chronic Myelogenous Leukemia trials Research Report on Relapsing Chronic Myelogenous Leukemia
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Single or Double Donor Umbilical Cord Blood Transplant in Treating Patients With High-Risk Hematologic Malignancies cyclophosphamide, fludarabine phosphate, mycophenolate mofetil - Accelerated Phase Chronic Myelogenous Leukemia, Acute Myeloid Leukemia With Multilineage Dysplasia Following Myelodysplastic Syndrome | Phase 2 | Withdrawn | University of Medicine and Dentistry of New Jersey | 2014-01-01 | 2016-07-14 | |
| Vorinostat, Tacrolimus, and Methotrexate in Preventing GVHD After Stem Cell Transplant in Patients With Hematological Malignancies vorinostat, tacrolimus, cyclosporine - Accelerated Phase Chronic Myelogenous Leukemia, Adult Acute Myeloid Leukemia in Remission | Phase 2 | Completed | National Cancer Institute (NCI) | 12 | 2013-06-01 | 2018-07-24 |
| Donor T Cells After Donor Stem Cell Transplant in Treating Patients With Hematologic Malignancies therapeutic allogeneic lymphocytes, laboratory biomarker analysis - Accelerated Phase Chronic Myelogenous Leukemia, Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities | Phase 2 | Completed | University of Chicago | 77 | 2013-04-04 | 2019-08-07 |
| Vaccine Therapy in Preventing Cytomegalovirus Infection in Patients With Hematological Malignancies Undergoing Donor Stem Cell Transplant tetanus-CMV fusion peptide vaccine, laboratory biomarker analysis - Accelerated Phase Chronic Myelogenous Leukemia, Adult Acute Lymphoblastic Leukemia in Remission | Phase 1 | Completed | City of Hope Medical Center | 36 | 2012-10-29 | 2024-04-02 |
| Mechanical Stimulation in Preventing Bone Density Loss in Patients Undergoing Donor Stem Cell Transplant management of therapy complications, musculoskeletal complications management/prevention - Accelerated Phase Chronic Myelogenous Leukemia, Adult Acute Lymphoblastic Leukemia in Remission | Not applicable | Withdrawn | Roswell Park Cancer Institute | 2012-05-01 | 2012-07-09 | |
| Donor Peripheral Stem Cell Transplant in Treating Patients With Hematolymphoid Malignancies therapeutic allogeneic lymphocytes - Adult Acute Myeloid Leukemia With Inv(16)(p13;q22), Adult Acute Myeloid Leukemia With t(15;17)(q22;q12) | Phase 1 | Completed | Robert Lowsky | 16 | 2012-01-01 | 2023-11-22 |
| Dasatinib and Cyclosporine in Treating Patients With Chronic Myelogenous Leukemia Refractory or Intolerant to Imatinib Mesylate dasatinib, diagnostic laboratory biomarker analysis, pharmacological study - Accelerated Phase Chronic Myelogenous Leukemia, Chronic Myelogenous Leukemia, BCR-ABL1 Positive | Phase 1 | Terminated | National Cancer Institute (NCI) | 4 | 2011-09-01 | 2014-04-02 |
| Cyclophosphamide for Prevention of Graft-Versus-Host Disease After Allogeneic Peripheral Blood Stem Cell Transplantation in Patients With Hematological Malignancies cyclophosphamide, cyclosporine, peripheral blood stem cell transplantation - Accelerated Phase Chronic Myelogenous Leukemia, Adult Acute Lymphoblastic Leukemia in Remission | Phase 2 | Completed | Fred Hutchinson Cancer Center | 43 | 2011-09-01 | 2017-05-19 |
| Methoxyamine and Fludarabine Phosphate in Treating Patients With Relapsed or Refractory Hematologic Malignancies fludarabine phosphate, methoxyamine, laboratory biomarker analysis - Adult Nasal Type Extranodal NK/T-cell Lymphoma, Anaplastic Large Cell Lymphoma | Phase 1 | Completed | Case Comprehensive Cancer Center | 20 | 2011-05-01 | 2015-08-13 |
| Supersaturated Calcium Phosphate Rinse in Preventing Oral Mucositis in Young Patients Undergoing Autologous or Donor Stem Cell Transplant supersaturated calcium phosphate rinse, placebo, questionnaire administration - Childhood Acute Lymphoblastic Leukemia in Remission, Childhood Acute Myeloid Leukemia in Remission | Phase 3 | Completed | Children's Oncology Group | 226 | 2011-03-01 | 2019-09-17 |
| Infection Prophylaxis and Management in Treating Cytomegalovirus (CMV) Infection in Patients With Hematologic Malignancies Previously Treated With Donor Stem Cell Transplant infection prophylaxis and management, laboratory biomarker analysis, flow cytometry - Hematopoietic/Lymphoid Cancer, Accelerated Phase Chronic Myelogenous Leukemia | Active not recruiting | City of Hope Medical Center | 153 | 2011-01-11 | 2026-10-22 | |
| MK2206 in Treating Younger Patients With Recurrent or Refractory Solid Tumors or Leukemia Akt inhibitor MK2206, diagnostic laboratory biomarker analysis, pharmacological study - Accelerated Phase Chronic Myelogenous Leukemia, Acute Leukemias of Ambiguous Lineage | Phase 1 | Completed | National Cancer Institute (NCI) | 45 | 2011-01-01 | 2014-04-29 |
| Palifermin in Preventing Chronic Graft-Versus-Host Disease in Patients Who Have Undergone Donor Stem Cell Transplant for Hematologic Cancer palifermin, flow cytometry, laboratory biomarker analysis - Accelerated Phase Chronic Myelogenous Leukemia, Adult Acute Lymphoblastic Leukemia in Remission | Not applicable | Completed | Martin, Paul | 6 | 2010-09-01 | 2014-04-02 |
| Infusion of Off-the-Shelf Expanded Cord Blood Cells to Augment Cord Blood Transplant in Patients With Hematologic Malignancies umbilical cord blood transplantation, fludarabine phosphate, cyclophosphamide - Accelerated Phase Chronic Myelogenous Leukemia, Adult Acute Myeloid Leukemia in Remission | Phase 2 | Completed | Nohla Therapeutics, Inc. | 15 | 2010-08-01 | 2019-03-05 |
| Deferasirox for Treating Patients Who Have Undergone Allogeneic Stem Cell Transplant and Have Iron Overload deferasirox - Iron Overload, Accelerated Phase Chronic Myelogenous Leukemia | Phase 2 | Terminated | City of Hope Medical Center | 1 | 2010-07-01 | 2019-06-18 |
| Plerixafor and Filgrastim For Mobilization of Donor Peripheral Blood Stem Cells Before A Donor Peripheral Blood Stem Cell Transplant in Treating Patients With Hematologic Malignancies plerixafor, filgrastim, peripheral blood stem cell transplantation - Accelerated Phase Chronic Myelogenous Leukemia, Adult Acute Lymphoblastic Leukemia in Remission | Not applicable | Terminated | Fred Hutchinson Cancer Center | 1 | 2010-06-01 | 2017-06-28 |
| Massage Therapy Given by Caregiver in Treating Quality of Life of Young Patients Undergoing Treatment for Cancer massage therapy, questionnaire administration, quality-of-life assessment - Accelerated Phase Chronic Myelogenous Leukemia, Acute Undifferentiated Leukemia | Not applicable | Completed | Wake Forest University Health Sciences | 80 | 2010-04-01 | 2018-07-02 |
| Rituximab in Preventing Acute Graft-Versus-Host Disease in a Donor Stem Cell Transplant for Hematologic Cancer rituximab, mycophenolate mofetil, tacrolimus - Accelerated Phase Chronic Myelogenous Leukemia, Adult Acute Lymphoblastic Leukemia in Remission | Phase 2 | Terminated | University of Nebraska | 20 | 2009-12-10 | 2023-09-06 |
| Sunitinib Malate in Treating HIV-Positive Patients With Cancer Receiving Antiretroviral Therapy sunitinib malate, pharmacological study, laboratory biomarker analysis - Accelerated Phase Chronic Myelogenous Leukemia, Acute Myeloid Leukemia With Multilineage Dysplasia Following Myelodysplastic Syndrome | Phase 1 | Completed | National Cancer Institute (NCI) | 42 | 2009-08-01 | 2014-03-17 |
| Obatoclax Mesylate, Vincristine Sulfate, Doxorubicin Hydrochloride, and Dexrazoxane Hydrochloride in Treating Young Patients With Relapsed or Refractory Solid Tumors, Lymphoma, or Leukemia dexrazoxane hydrochloride, doxorubicin hydrochloride, obatoclax mesylate - Acute Leukemias of Ambiguous Lineage, Acute Undifferentiated Leukemia | Phase 1 | Terminated | National Cancer Institute (NCI) | 22 | 2009-06-01 | 2014-05-01 |
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Precursor Cell Lymphoblastic Leukemia-Lymphoma (56) · Leukemia, Myeloid, Acute (49) · Blast Crisis (46) · Congenital Abnormalities (42) · Leukemia, Myeloid, Accelerated Phase (42) · Leukemia, Lymphocytic, Chronic, B-Cell (36) · Leukemia, Myeloid, Chronic-Phase (36) · Burkitt Lymphoma (34) · Lymphoma, Large B-Cell, Diffuse (32) · Leukemia, Myelomonocytic, Chronic (30) · Lymphoma, Follicular (30) · Lymphoma, B-Cell, Marginal Zone (29) · Lymphoma, Mantle-Cell (29) · Lymphoma, T-Cell, Cutaneous (29) · Mycosis Fungoides (29)
Disease Attributes (68) · Hematologic Diseases (68) · Hemic and Lymphatic Diseases (68) · Leukemia (68) · Neoplasms by Histologic Type (68) · Pathologic Processes (68) · Pathological Conditions, Signs and Symptoms (68) · Chronic Disease (67) · Leukemia, Myeloid (67) · Neoplasms (67) · Bone Marrow Diseases (66) · Immune System Diseases (56) · Immunoproliferative Disorders (56) · Leukemia, Lymphoid (56) · Lymphatic Diseases (56)
fludarabine phosphate (14) · Whole-Body Irradiation (11) · Cyclosporine (10) · Mycophenolic Acid (10) · Peripheral Blood Stem Cell Transplantation (10) · Cyclophosphamide (7) · Tacrolimus (7) · Imatinib Mesylate (6) · Transplantation (6) · Vorinostat (6) · Busulfan (5) · Flow Cytometry (5) · Therapeutics (5) · Antilymphocyte Serum (4) · Cytarabine (4)
National Cancer Institute (NCI) (35) · Fred Hutchinson Cancer Center (15) · Case Comprehensive Cancer Center (3) · City of Hope Medical Center (3) · Children's Oncology Group (2) · Roswell Park Cancer Institute (2) · Fred Hutchinson Cancer Research Center/University of Washington Cancer Consortium (1) · Martin, Paul (1) · Nohla Therapeutics, Inc. (1) · Robert Lowsky (1) · University of Chicago (1) · University of Medicine and Dentistry of New Jersey (1) · University of Nebraska (1) · Wake Forest University Health Sciences (1)
United States (67) · Italy (4) · Canada (3) · Germany (2) · Australia (1)
Brenda Sandmaier (4) · Francis Giles (3) · Jorge Cortes (3) · Maryam Fouladi (3) · Paul Martin (3) · Jean-Pierre Issa (2) · Richard Aplenc (2) · Ryotaro Nakamura (2) · B. Smith (1) · Brenda Cooper (1) · Brenda Cooper, MD (1) · Christopher Porter (1) · Colleen Delaney (1) · David Maloney (1) · Douglas Ross (1)
PMID 32499241, PMID 18974373, PMID 19900571, PMID 20460644, PMID 21791475, PMID 22259028, PMID 23393050, PMID 23443507, PMID 23660685, PMID 24362550, PMID 24474568, PMID 26764356, PMID 26853648, PMID 28817727, PMID 29572391, PMID 30562587, PMID 32628342, PMID 33420905, PMID 35445027, PMID 36282798
P30CA015704 (9), P01CA018029 (7), U01CA062461 (6), N01CM62202 (3), U01CA062505 (3), U01CA097452 (3), U01CA062502 (2), U01CA070095 (2), N01CM17003 (1), P01CA015396 (1), P01CA078902 (1), P01HL036444 (1), P30CA006973 (1), P30CA036727 (1), P30CA046592 (1)