3 completed, 2 terminated, 1 active not recruiting. 4 Phase 2, 2 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 4 | Completed 2, Active not recruiting 1, Terminated 1 |
| Phase 1 | 2 | Completed 1, Terminated 1 |
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Infusion of Expanded Cord Blood Cells in Addition to Single Cord Blood Transplant in Treating Patients With Acute Leukemia, Chronic Myeloid Leukemia, or Myelodysplastic Syndromes Dilanubicel, Cyclophosphamide, Fludarabine - Acute Biphenotypic Leukemia, Acute Lymphoblastic Leukemia | Phase 2 | Active not recruiting | Fred Hutchinson Cancer Center | 31 | 2022-05-10 | 2026-07-10 |
| NLA101 in Adults Receiving High Dose Chemotherapy for AML NLA101, Standard of Care (SOC) chemotherapy - Leukemia, Myeloid, Acute | Phase 2 | Terminated | Nohla Therapeutics, Inc. | 146 | 2018-01-24 | 2021-03-30 |
| Donor Umbilical Cord Blood Transplant With or Without Ex-vivo Expanded Cord Blood Progenitor Cells in Treating Patients With Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia, Chronic Myelogenous Leukemia, or Myelodysplastic Syndromes Cyclophosphamide, Cyclosporine, Ex Vivo-Expanded Cord Blood Progenitor Cell Infusion - Acute Biphenotypic Leukemia, Acute Lymphoblastic Leukemia in Remission | Phase 2 | Completed | Nohla Therapeutics, Inc. | 163 | 2012-12-11 | 2021-07-06 |
| Expanded Cord Blood Cell Infusion Following Combination Chemotherapy in Younger Patients With Relapsed or Refractory Acute Myeloid Leukemia Ex-Vivo Expanded Cord Blood Progenitor Cell Infusion, Cytarabine, Filgrastim - Acute Leukemia of Ambiguous Lineage, Acute Myeloid Leukemia | Phase 1 | Terminated | Nohla Therapeutics, Inc. | 7 | 2012-12-10 | 2019-03-01 |
| Infusion of Off-the-Shelf Expanded Cord Blood Cells to Augment Cord Blood Transplant in Patients With Hematologic Malignancies umbilical cord blood transplantation, fludarabine phosphate, cyclophosphamide - Accelerated Phase Chronic Myelogenous Leukemia, Adult Acute Myeloid Leukemia in Remission | Phase 2 | Completed | Nohla Therapeutics, Inc. | 15 | 2010-08-01 | 2019-03-05 |
| Clofarabine, Cytarabine, and Filgrastim Followed by Infusion of Non-HLA Matched Ex Vivo Expanded Cord Blood Progenitors in Treating Patients With Acute Myeloid Leukemia cytarabine, clofarabine, filgrastim - Adult Acute Megakaryoblastic Leukemia (M7), Adult Acute Minimally Differentiated Myeloid Leukemia (M0) | Phase 1 | Completed | Nohla Therapeutics, Inc. | 29 | 2009-12-01 | 2019-03-01 |
Leukemia, Biphenotypic, Acute (3) · Leukemia, Myeloid, Acute (3) · Anemia, Refractory, with Excess of Blasts (2) · Congenital Abnormalities (2) · Leukemia, Myelogenous, Chronic, BCR-ABL Positive (2) · Myelodysplastic Syndromes (2) · Anemia, Refractory (1) · Bacterial Infections (1) · Hematologic Neoplasms (1) · Leukemia, Erythroblastic, Acute (1) · Leukemia, Megakaryoblastic, Acute (1) · Leukemia, Monocytic, Acute (1) · Leukemia, Myeloid, Accelerated Phase (1) · Leukemia, Myeloid, Chronic-Phase (1) · Leukemia, Myelomonocytic, Acute (1)
Cord Blood Stem Cell Transplantation (3) · Cyclophosphamide (3) · Whole-Body Irradiation (3) · fludarabine phosphate (3) · Cyclosporine (2) · Cytarabine (2) · Filgrastim (2) · Mycophenolic Acid (2) · Thiotepa (2) · Clofarabine (1) · Drug Therapy (1) · Granulocyte Colony-Stimulating Factor (1) · Standard of Care (1) · Transplantation (1) · fludarabine (1)
United States (6) · Australia (1) · South Korea (1)
Colleen Delaney (2) · Filippo Milano (2) · Ann Dahlberg (1) · Martin S Tallman, MD (1) · Naval G Daver, MD (1)
P30CA015704 (4), P50HL110787 (2), RC2HL101844 (1)