2 completed, 1 unknown, 1 withdrawn. 3 Phase 1, 2 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 3 | Completed 1, Unknown 1, Withdrawn 1 |
| Phase 2 | 2 | Completed 1, Unknown 1 |
Follow Recurrent Primitive Neuroectodermal Tumor: new trials by email Literature Review of Recurrent Primitive Neuroectodermal Tumor trials Research Report on Recurrent Primitive Neuroectodermal Tumor
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Chemotherapy and Donor Stem Transplant for the Treatment of Patients With High Grade Brain Cancer Etoposide, Fludarabine Phosphate, Hematopoietic Cell Transplantation - Anaplastic Ependymoma, Atypical Teratoid/Rhabdoid Tumor | Phase 1 | Withdrawn | M.D. Anderson Cancer Center | 2021-01-14 | 2024-10-26 | |
| Wild-Type Reovirus in Combination With Sargramostim in Treating Younger Patients With High-Grade Relapsed or Refractory Brain Tumors Laboratory Biomarker Analysis, Sargramostim, Wild-type Reovirus - Childhood Astrocytoma, Childhood Atypical Teratoid/Rhabdoid Tumor | Phase 1 | Completed | Mayo Clinic | 6 | 2015-06-21 | 2023-04-24 |
| Temozolomide and Irinotecan Hydrochloride With or Without Bevacizumab in Treating Young Patients With Recurrent or Refractory Medulloblastoma or CNS Primitive Neuroectodermal Tumors Bevacizumab, Irinotecan Hydrochloride, Temozolomide - Central Nervous System Neoplasm, Pineoblastoma | Phase 2 | Completed | National Cancer Institute (NCI) | 108 | 2010-11-22 | 2021-07-23 |
| Melphalan, Carboplatin, Mannitol, and Sodium Thiosulfate in Treating Patients With Recurrent or Progressive CNS Embryonal or Germ Cell Tumors Carboplatin, Mannitol, Melphalan - Central Nervous System Embryonal Neoplasm, Embryonal Tumor With Multilayered Rosettes, C19MC-Altered | Phase 1 / Phase 2 | Unknown | OHSU Knight Cancer Institute | 17 | 2009-07-09 | 2021-10-26 |
Medulloblastoma (4) · Neuroectodermal Tumors, Primitive (4) · Brain Neoplasms (2) · Glioma (2) · Rhabdoid Tumor (2) · Astrocytoma (1) · Central Nervous System Neoplasms (1) · Choroid Plexus Carcinoma (1) · Diffuse Intrinsic Pontine Glioma (1) · Ependymoma (1) · Neoplasms, Germ Cell and Embryonal (1) · Neuroectodermal Tumors, Primitive, Peripheral (1) · Oligodendroglioma (1) · Pinealoma (1)
Neoplasms (4) · Neoplasms by Histologic Type (4) · Neoplasms, Glandular and Epithelial (4) · Neoplasms, Nerve Tissue (4) · Neoplasms, Neuroepithelial (4) · Neuroectodermal Tumors (4) · Brain Diseases (3) · Central Nervous System Diseases (3) · Neoplasms by Site (3) · Neoplasms, Germ Cell and Embryonal (3) · Nervous System Diseases (3) · Nervous System Neoplasms (3) · Central Nervous System Neoplasms (2) · Glioma (2) · Neoplasms, Complex and Mixed (2)
Melphalan (2) · Antilymphocyte Serum (1) · Bevacizumab (1) · Carboplatin (1) · Colony-Stimulating Factors (1) · Disulfides (1) · Etoposide (1) · Hematopoietic Stem Cell Transplantation (1) · Immunoglobulin G (1) · Irinotecan (1) · Mannitol (1) · Mycophenolic Acid (1) · Stem Cell Transplantation (1) · Tacrolimus (1) · Temozolomide (1)
M.D. Anderson Cancer Center (1) · Mayo Clinic (1) · National Cancer Institute (NCI) (1) · OHSU Knight Cancer Institute (1)
United States (3) · Australia (1) · Canada (1) · New Zealand (1) · Puerto Rico (1)
Adam S Levy (1) · Edward A Neuwelt (1) · Kris M Mahadeo, MD (1) · Richard Bram (1)
P30CA015083 (1), R01NS044687 (1), U10CA098543 (1), U10CA180886 (1)