2 completed, 1 terminated. 3 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 3 | Completed 2, Terminated 1 |
Follow Recurrent Childhood Spinal Cord Neoplasm: new trials by email Literature Review of Recurrent Childhood Spinal Cord Neoplasm trials Research Report on Recurrent Childhood Spinal Cord Neoplasm
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Gamma-Secretase Inhibitor RO4929097 in Treating Young Patients With Relapsed or Refractory Solid Tumors, CNS Tumors, Lymphoma, or T-Cell Leukemia gamma-secretase/Notch signalling pathway inhibitor RO4929097, diagnostic laboratory biomarker analysis, pharmacological study - Childhood Atypical Teratoid/Rhabdoid Tumor, Childhood Central Nervous System Choriocarcinoma | Phase 1 | Terminated | National Cancer Institute (NCI) | 129 | 2010-03-01 | 2014-11-05 |
| Vorinostat and Temozolomide in Treating Young Patients With Relapsed or Refractory Primary Brain Tumors or Spinal Cord Tumors vorinostat, temozolomide, diagnostic laboratory biomarker analysis - Childhood Atypical Teratoid/Rhabdoid Tumor, Childhood Central Nervous System Choriocarcinoma | Phase 1 | Completed | National Cancer Institute (NCI) | 27 | 2010-02-01 | 2013-05-03 |
| ABT-888 and Temozolomide in Treating Young Patients With Recurrent or Refractory CNS Tumors veliparib, temozolomide, pharmacological study - Childhood Atypical Teratoid/Rhabdoid Tumor, Childhood Central Nervous System Germ Cell Tumor | Phase 1 | Completed | National Cancer Institute (NCI) | 31 | 2009-07-01 | 2014-07-09 |
Astrocytoma (3) · Choroid Plexus Neoplasms (3) · Familial ependymoma (3) · Medulloblastoma (3) · Oligodendroglioma (3) · Optic Nerve Glioma (3) · Rhabdoid Tumor (3) · Spinal Cord Neoplasms (3) · Adenoma, Acidophil (1) · Adenoma, Basophil (1) · Adenoma, Chromophobe (1) · Burkitt Lymphoma (1) · Dendritic Cell Sarcoma, Interdigitating (1) · Leukemia, Large Granular Lymphocytic (1) · Lymphoma, Large-Cell, Anaplastic (1)
Brain Diseases (3) · Brain Neoplasms (3) · Central Nervous System Diseases (3) · Central Nervous System Neoplasms (3) · Cerebral Ventricle Neoplasms (3) · Cranial Nerve Diseases (3) · Cranial Nerve Neoplasms (3) · Eye Diseases (3) · Glioma (3) · Neoplasms (3) · Neoplasms by Histologic Type (3) · Neoplasms by Site (3) · Neoplasms, Complex and Mixed (3) · Neoplasms, Germ Cell and Embryonal (3) · Neoplasms, Glandular and Epithelial (3)
Temozolomide (2) · 2,2-dimethyl-N-(6-oxo-6,7-dihydro-5H-dibenzo(b,d)azepin-7-yl)-N'-(2,2,3,3,3-pentafluoropropyl)malonamide (1) · Calcium Dobesilate (1) · Dexamethasone (1) · Vorinostat (1) · veliparib (1)
National Cancer Institute (NCI) (3)
United States (3) · Canada (2)
Jack Su (1) · Najat Daw (1) · Trent Hummel (1)
U01CA097452 (2), U01CA081457 (1)