6 completed, 1 terminated, 1 withdrawn. 8 Phase 1, 5 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 8 | Completed 6, Terminated 1, Withdrawn 1 |
| Phase 2 | 5 | Completed 3, Terminated 1, Withdrawn 1 |
Follow Pulmonary Emphysema: new trials by email Literature Review of Pulmonary Emphysema trials Research Report on Pulmonary Emphysema
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Study to Evaluate Safety, Tolerability and Pharmacokinetics of Two Different Doses of Alpha1-Proteinase Inhibitor Subcutaneous (Human) 15% in Participants With Alpha1-Antitrypsin Deficiency Alpha-1 15%, Liquid Alpha1-Proteinase Inhibitor (Human) - Alpha1-Antitrypsin Deficiency | Phase 1 / Phase 2 | Completed | Grifols Therapeutics LLC | 17 | 2021-12-16 | 2026-10-08 |
| Clinical Study of the Efficacy and Safety of the Application of Allogeneic Mesenchymal (Stromal) Cells of Bone Marrow, Cultured Under the Hypoxia in the Treatment of Patients With Severe Pulmonary Emphysema Mesenchymal stem cells, Reference therapy: 400 mL of 0.9% NaCl solution - Pulmonary Emphysema | Phase 1 / Phase 2 | Withdrawn | Federal Research Clinical Center of Federal Medical & Biological Agency, Russia | 2014-03-01 | 2018-01-09 | |
| AeriSeal System for Lung Volume Reduction AeriSeal System - Emphysema, Chronic Obstructive Pulmonary Disease (COPD) | Phase 1 / Phase 2 | Completed | Aeris Therapeutics | 55 | 2009-11-01 | 2013-06-26 |
| Israeli Biologic Lung Volume Reduction (BLVR) Phase 1 Emphysema Study Biologic Lung Volume Reduction (BLVR) - 10 mL Hydrogel - Pulmonary Emphysema, Chronic Obstructive Pulmonary Disease | Phase 1 | Completed | Aeris Therapeutics | 16 | 2007-05-01 | 2010-01-18 |
| US 10 mL Biologic Lung Volume Reduction (BLVR) Phase 1 Emphysema Study BLVR System - Pulmonary Emphysema | Phase 1 | Completed | Aeris Therapeutics | 6 | 2006-06-01 | 2008-03-06 |
| US 10 mL Bronchoscopic Lung Volume Reduction (BLVR) Phase 1 Emphysema Study - Initial Formulation BLVR - Pulmonary Emphysema | Phase 1 | Completed | Aeris Therapeutics | 6 | 2005-04-01 | 2008-03-06 |
| Israeli 10 mL Bronchoscopic Lung Volume Reduction (BLVR) Phase 1/2 Emphysema Study - Initial Formulation BLVR Hydrogel - Pulmonary Emphysema | Phase 1 / Phase 2 | Terminated | Aeris Therapeutics | 4 | 2005-01-01 | 2008-03-06 |
| Yoga for Treating Shortness of Breath in Chronic Obstructive Pulmonary Disease (COPD) yoga - Pulmonary Disease, Chronic Obstructive, Lung Diseases, Obstructive | Phase 1 / Phase 2 | Completed | National Center for Complementary and Integrative Health (NCCIH) | 36 | 2003-01-01 | 2006-08-18 |
Emphysema (7) · Pulmonary Disease, Chronic Obstructive (7) · Lung Diseases (4) · Lung Diseases, Obstructive (2) · Pathologic Processes (2) · Respiratory Tract Diseases (2) · Bronchitis, Chronic (1) · Digestive System Diseases (1) · Genetic Diseases, Inborn (1) · Hypoxia (1) · Liver Diseases (1) · Respiratory Aspiration (1) · Subcutaneous Emphysema (1) · alpha 1-Antitrypsin Deficiency (1)
Chronic Disease (8) · Disease Attributes (8) · Pathological Conditions, Signs and Symptoms (8) · Lung Diseases, Obstructive (6) · Pathologic Processes (6) · Respiratory Tract Diseases (6) · Lung Diseases (4) · Bronchial Diseases (1) · Bronchitis (1) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (1) · Infections (1) · Pulmonary Disease, Chronic Obstructive (1) · Respiration Disorders (1) · Respiratory Tract Infections (1) · Signs and Symptoms (1)
15-keto-17-phenyl-18,19,20-trinorprostaglandin F2 alpha-1-isopropyl ester (1) · Hydrogels (1) · Pneumonectomy (1) · Yoga (1)
Aeris Therapeutics (5) · Federal Research Clinical Center of Federal Medical & Biological Agency, Russia (1) · Grifols Therapeutics LLC (1) · National Center for Complementary and Integrative Health (NCCIH) (1)
United States (4) · Israel (3) · Austria (1) · France (1) · Germany (1) · Russia (1)
Alexander V Averyanov, MD, PhD (1) · Issahar Ben-Dov, MD (1) · John J. Reilly, MD (1) · Virginia Carrieri-Kohlman, RN, DNSc (1) · Yael Refaely, MD (1)