26 terminated. 26 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 26 | Terminated 26 |
Follow Pulmonary Disease, Chronic Obstructive: new trials by email Literature Review of Pulmonary Disease, Chronic Obstructive trials Research Report on Pulmonary Disease, Chronic Obstructive
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| ANTES B+ Clinical Trial Trelegy Ellipta 100/62.5/25Mcg Inh 30D, Brimica, Duaklir - Chronic Obstructive Pulmonary Disease | Phase 4 | Terminated | Fundacio Privada Mon Clinic Barcelona | 48 | 2024-02-29 | 2025-08-14 |
| Treatment Efficacy of Systemic Corticosteroids in AECOPD Patients With Higher Blood Eosinophil Levels Prednisone, Placebo - Acute Exacerbation of COPD, Corticosteroid | Phase 4 | Terminated | Capital Medical University | 11 | 2023-03-05 | 2024-08-28 |
| Substudy of Protocol 2019-002498-80 - NCT04223050: Comparing Mortality for Low vs High Peripheral Oxygen Saturation in COPD-patients With Acute Exacerbation (O2flow-COPD) Oxygen - Chronic Obstructive Pulmonary Disease | Phase 4 | Terminated | Mikkel Brabrand | 23 | 2021-12-16 | 2025-03-11 |
| Comparing Mortality for Low vs High Peripheral Oxygen Saturation in COPD-patients With Acute Exacerbation Oxygen gas - COPD Exacerbation, Chronic Obstructive Pulmonary Disease Exacerbation | Phase 4 | Terminated | Esbjerg Hospital - University Hospital of Southern Denmark | 23 | 2020-02-03 | 2026-03-11 |
| Inhaled Long-acting Bronchodilators With or Without Inhaled Glucocorticosteroids for Preventing Hospitalizations and Death in Elderly Patients With Chronic Obstructive Pulmonary Disease Bronchodilator Agents - Pulmonary Disease, Chronic Obstructive | Phase 4 | Terminated | Università degli Studi di Ferrara | 843 | 2018-11-11 | 2022-12-28 |
| Salmeterol/Fluticasone 50/500 mcg Inhalation Powder Via Capsair vs Seretide Diskus 500 mcg Inhalation Powder in Patients With COPD Salmeterol/Fluticasone Capsair®, Salmeterol/Fluticasone Diskus® - COPD | Phase 4 | Terminated | Neutec Ar-Ge San ve Tic A.Ş | 64 | 2018-04-13 | 2022-05-20 |
| Targeted AntiBiotics for Chronic Pulmonary Diseases Piperacillin/tazobactam, Ciprofloxacin - COPD, Respiratory Tract Infections | Phase 4 | Terminated | Chronic Obstructive Pulmonary Disease Trial Network, Denmark | 51 | 2018-01-10 | 2023-05-25 |
| Nebulizer Versus Dry Powdered Inhalers for Chronic Obstructive Pulmonary Disease (COPD) Nebulizers, Dry Powder Inhaler, Brovana - COPD, COPD Exacerbation | Phase 4 | Terminated | Wake Forest University Health Sciences | 40 | 2017-10-03 | 2021-06-22 |
| Effect of Losartan on Airway Mucociliary Dysfunction in Patients With COPD and Chronic Bronchitis Losartan 50 mg, Losartan 100 mg - COPD, Chronic Bronchitis | Phase 4 | Terminated | University of Miami | 31 | 2016-03-31 | 2020-08-20 |
| A Study of Arformoterol Tartrate Inhalation Solution and Tiotropium Bromide on Re-hospitalization in Chronic Obstructive Pulmonary Disease (COPD) Subjects Arformoterol tartrate inhalation solution, Tiotropium - Chronic Obstructive Pulmonary Disease (COPD) | Phase 4 | Terminated | Sumitomo Pharma America, Inc. | 66 | 2014-11-01 | 2018-06-27 |
| Ventilator Adapters for Combivent Respimat Combivent Respimat via tee adapter, Combivent Respimat via ventilator adapter - Pulmonary Disease, Chronic Obstructive | Phase 4 | Terminated | Boehringer Ingelheim | 11 | 2013-10-14 | 2025-02-10 |
| Inhaled Fluticasone Effects on Upper Airway Patency in Obstructive Lung Disease Inhaled Fluticasone Propionate - Asthma, Chronic Obstructive Pulmonary Disease | Phase 4 | Terminated | VA Office of Research and Development | 25 | 2013-03-12 | 2020-02-05 |
| Dose of Corticosteroids in COPD Low Dose Corticosteroids, High Dose Corticosteroids - COPD | Phase 4 | Terminated | Rutgers, The State University of New Jersey | 89 | 2012-05-03 | 2024-04-10 |
| Effects of Symbicort on the Ventilatory Kinematics Budesonide, Symbicort - Chronic Obstructive Lung Disease | Phase 4 | Terminated | Columbia University | 9 | 2012-03-01 | 2016-09-02 |
| Collateral Ventilation Effects on Response to AeriSeal System Treatment in Upper Lobe Predominant Emphysema Emphysematous Lung Sealant - Pulmonary Emphysema | Phase 4 | Terminated | Aeris Therapeutics | 100 | 2012-02-01 | 2013-11-14 |
| Changes in Cardiac Function in COPD Patients After Administration of Budesonide/Formoterol (Symbicort®) Versus Placebo Budesonide / Formoterol, Placebo - Chronic Obstructive Pulmonary Disease (COPD) | Phase 4 | Terminated | Brigham and Women's Hospital | 5 | 2012-01-01 | 2017-06-14 |
| Effect of Inhaled Steroids on Gene Expression in the Lungs - 2 Beclomethasone - Chronic Obstructive Pulmonary Disease (COPD) | Phase 4 | Terminated | Weill Medical College of Cornell University | 24 | 2010-11-01 | 2018-01-25 |
| Bronchodilators and Respiratory Mechanics in Chronic Obstructive Pulmonary Disease (COPD) Patients Salbutamol + Tiotropium, Placebo + Tiotropium - Chronic Obstructive Pulmonary Disease | Phase 4 | Terminated | IRCCS Azienda Ospedaliero-Universitaria di Bologna | 20 | 2008-09-01 | 2012-07-17 |
| ADVAIR DISKUS® (Fluticasone Propionate/Salmeterol) Inhaler Versus SEREVENT DISKUS® (Salmeterol) Inhlaer On Inflammatory Cells And Markers In Chronic Obstructive Pulmonary Disease. ADVAIR DISKUS® and SEREVENT DISKUS® Inhalers Are Trademarks of the GSK Group of Companies. Salmeterol, Fluticasone Propionate/Salmeterol Combination Product - Pulmonary Disease, Chronic Obstructive | Phase 4 | Terminated | GlaxoSmithKline | 180 | 2006-12-01 | 2016-10-28 |
| Tiotropium + Procaterol vs Tiotropium + Placebo in COPD Patients Procaterol, Tiotropium - Pulmonary Disease, Chronic Obstructive | Phase 4 | Terminated | Otsuka Pharmaceutical, Inc., Philippines | 50 | 2006-05-01 | 2009-12-17 |
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Bronchitis, Chronic (5) · Asthma (2) · Emphysema (2) · Respiratory Tract Infections (2) · Bronchiectasis (1) · Inflammation (1) · Lung Diseases, Obstructive (1) · Pneumonia (1) · Pseudomonas Infections (1) · Pulmonary Emphysema (1) · Sleep Apnea, Obstructive (1)
Chronic Disease (26) · Disease Attributes (26) · Lung Diseases (26) · Pathologic Processes (26) · Pathological Conditions, Signs and Symptoms (26) · Respiratory Tract Diseases (26) · Lung Diseases, Obstructive (25) · Bronchial Diseases (7) · Infections (6) · Bronchitis (5) · Respiratory Tract Infections (4) · Hypersensitivity (2) · Hypersensitivity, Immediate (2) · Immune System Diseases (2)
Salmeterol Xinafoate (5) · Tiotropium Bromide (4) · Formoterol Fumarate (3) · Budesonide (2) · Budesonide, Formoterol Fumarate Drug Combination (2) · Fluticasone (2) · GSK573719 (2) · Prednisone (2) · olodaterol (2) · telithromycin (2) · tiotropium-olodaterol (2) · Adrenal Cortex Hormones (1) · Albuterol (1) · Anti-Bacterial Agents (1) · Azithromycin (1)
Boehringer Ingelheim (2) · IRCCS Azienda Ospedaliero-Universitaria di Bologna (2) · Sanofi (2) · Aeris Therapeutics (1) · Brigham and Women's Hospital (1) · Capital Medical University (1) · Chronic Obstructive Pulmonary Disease Trial Network, Denmark (1) · Columbia University (1) · Esbjerg Hospital - University Hospital of Southern Denmark (1) · Fundacio Privada Mon Clinic Barcelona (1) · GlaxoSmithKline (1) · Hospital Universitario Getafe (1) · Leiden University Medical Center (1) · Mikkel Brabrand (1) · Neutec Ar-Ge San ve Tic A.Ş (1)
United States (11) · Denmark (3) · Italy (3) · Spain (2) · Turkey (Türkiye) (2) · Canada (1) · China (1) · Germany (1) · Israel (1) · Netherlands (1) · Philippines (1)
Abundio A Balgos, MD (1) · Bartolome R Celli, MD (1) · Edibe Taylan (1) · Janine McDermott, MS CCRP (1) · Jeffrey L Carson, MD (1) · Jens-Ulrik Jensen, MD, Consultant, Phd (1) · Jill A Ohar, MD, FCCP (1) · Matthew Bartels, MD, MPH (1) · Mihaela Teodorescu, MD (1) · Peter Hallas, MD (1) · Peter J. Sterk, MD, PhD (1) · Phyllis Diener, BS, MT (ASCP) (1) · Rafael Calderon, MD (1)
PMID 18039368, PMID 19841453, PMID 22123804, PMID 23667615, PMID 25836351, PMID 26659582, PMID 26696093, PMID 31238116, PMID 33060632, PMID 35118915, PMID 35124256, PMID 37247957, PMID 38844921, PMID 40739568
2019 (2), 2023 (1), R01HL133240 (1), R01HL139365 (1)