9 completed, 1 active not recruiting, 1 recruiting, 1 terminated. 13 Phase 3, 7 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 13 | Completed 9, Active not recruiting 1, Recruiting 1, Terminated 1, Withdrawn 1 |
| Phase 2 | 7 | Completed 6, Active not recruiting 1 |
Follow Pulmonary Aspergillosis: new trials by email Literature Review of Pulmonary Aspergillosis trials Research Report on Pulmonary Aspergillosis
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Randomized Trial of Prednisolone, Itraconazole, or Their Combination in Allergic Bronchopulmonary Aspergillosis Prednisolone, Itraconazole - Allergic Bronchopulmonary Aspergillosis | Phase 3 | Recruiting | Post Graduate Institute of Medical Education and Research, Chandigarh | 300 | 2023-12-01 | 2025-02-28 |
| Safety and Efficacy of PC945 (Opelconazole) in Combination With Other Antifungal Therapy for the Treatment of Refractory Invasive Pulmonary Aspergillosis (OPERA-T Study) PC945, Placebo - Refractory IPA | Phase 3 | Terminated | Pulmocide Ltd | 85 | 2022-06-14 | 2026-04-30 |
| Deflazacort Vs. Prednisolone in Acute-stage ABPA Deflazacort, Prednisolone - Allergic Bronchopulmonary Aspergillosis | Phase 2 / Phase 3 | Active not recruiting | Post Graduate Institute of Medical Education and Research, Chandigarh | 150 | 2020-01-15 | 2025-02-28 |
| Study to Evaluate the Efficacy and Safety of Ibrexafungerp in Patients With Fungal Diseases That Are Refractory to or Intolerant of Standard Antifungal Treatment Ibrexafungerp - Invasive Candidiasis, Mucocutaneous Candidiasis | Phase 3 | Completed | Scynexis, Inc. | 233 | 2017-04-01 | 2024-11-20 |
| A Study Evaluating Vitamin D in Allergic Bronchopulmonary Aspergillosis Complicating Asthma Glucocorticoids, Vitamin D - Allergic Bronchopulmonary Aspergilloses | Phase 2 / Phase 3 | Completed | Post Graduate Institute of Medical Education and Research, Chandigarh | 30 | 2016-12-01 | 2018-08-23 |
| Anemia Studies in Chronic Kidney Disease: Erythropoiesis Via a Novel Prolyl Hydroxylase Inhibitor Daprodustat-Dialysis (ASCEND-D) Daprodustat, rhEPO, Placebo - Anaemia, Aspergillosis, Allergic Bronchopulmonary | Phase 3 | Completed | GlaxoSmithKline | 2964 | 2016-09-28 | 2021-12-03 |
| A Randomized Trial of Itraconazole in Acute Stages of Allergic Bronchopulmonary Aspergillosis Itraconazole, Glucocorticoids - Allergic Bronchopulmonary Aspergillosis | Phase 2 / Phase 3 | Completed | Post Graduate Institute of Medical Education and Research, Chandigarh | 191 | 2014-05-01 | 2022-10-07 |
| A Study of the Safety and Efficacy of Posaconazole Versus Voriconazole for the Treatment of Invasive Aspergillosis (MK-5592-069) Posaconazole, Voriconazole, Placebo - Fungal Infections, Invasive Pulmonary Aspergillosis | Phase 3 | Completed | Merck Sharp & Dohme LLC | 585 | 2013-09-25 | 2024-01-18 |
| Voriconazole Versus Oral Steroids in Allergic Bronchopulmonary Aspergillosis Prednisolone, Voriconazole - Allergic Bronchopulmonary Aspergillosis | Phase 2 / Phase 3 | Completed | Post Graduate Institute of Medical Education and Research, Chandigarh | 50 | 2013-06-01 | 2017-12-12 |
| A Randomized Controlled Trial of Inhaled Amphotericin B for Maintaining Remission in Allergic Bronchopulmonary Aspergillosis Inhaled budesonide, Inhaled amphotericin - Allergic Bronchopulmonary Aspergillosis | Phase 2 / Phase 3 | Completed | Post Graduate Institute of Medical Education and Research, Chandigarh | 21 | 2013-05-01 | 2015-08-05 |
| Voriconazole And Anidulafungin Combination For Invasive Aspergillosis In Pediatric Subjects Voriconazole, Anidulafungin - Aspergillosis, Invasive Pulmonary Aspergillosis | Phase 3 | Withdrawn | Pfizer | 2012-05-01 | 2012-05-11 | |
| Monotherapy of Itraconazole Versus Prednisolone in Allergic Bronchopulmonary Aspergillosis Glucocorticoids, Itraconazole - Allergic Bronchopulmonary Aspergillosis | Phase 2 / Phase 3 | Completed | Post Graduate Institute of Medical Education and Research, Chandigarh | 100 | 2011-04-01 | 2017-03-16 |
| Trial on the Efficacy and Safety of Two Different Glucocorticoid Dose Regimens in Allergic Bronchopulmonary Aspergillosis Glucocorticoids - Allergic Bronchopulmonary Aspergillosis | Phase 2 / Phase 3 | Completed | Post Graduate Institute of Medical Education and Research, Chandigarh | 92 | 2009-04-01 | 2015-02-24 |
Aspergillosis, Allergic Bronchopulmonary (10) · Invasive Pulmonary Aspergillosis (4) · Asthma (2) · Anemia (1) · Aspergillosis (1) · Blastomycosis (1) · Candidiasis, Chronic Mucocutaneous (1) · Candidiasis, Invasive (1) · Candidiasis, Vulvovaginal (1) · Coccidioidomycosis (1) · Histoplasmosis (1) · Mycoses (1) · Neuroaspergillosis (1) · Renal Insufficiency, Chronic (1)
Bacterial Infections and Mycoses (13) · Infections (13) · Lung Diseases (13) · Lung Diseases, Fungal (13) · Respiratory Tract Diseases (13) · Aspergillosis (12) · Mycoses (12) · Hypersensitivity (10) · Hypersensitivity, Immediate (10) · Immune System Diseases (10) · Respiratory Hypersensitivity (10) · Respiratory Tract Infections (10) · Invasive Fungal Infections (4) · Bronchial Diseases (2)
Glucocorticoids (4) · Prednisolone (4) · Itraconazole (3) · Voriconazole (3) · Azoles (2) · Anidulafungin (1) · GSK1278863 (1) · Steroids (1) · Vitamin D (1) · deflazacort (1) · ibrexafungerp (1) · posaconazole (1)
Post Graduate Institute of Medical Education and Research, Chandigarh (8) · GlaxoSmithKline (1) · Merck Sharp & Dohme LLC (1) · Pfizer (1) · Pulmocide Ltd (1) · Scynexis, Inc. (1)
India (10) · Austria (3) · Germany (3) · Spain (3) · United Kingdom (3) · United States (3) · Argentina (2) · Australia (2) · Belgium (2) · Brazil (2) · Canada (2) · France (2) · Greece (2) · Italy (2) · Netherlands (2)
PMID 26585431, PMID 29331473, PMID 30049743, PMID 30561849, PMID 33549194, PMID 33744933, PMID 34739194, PMID 36005278, PMID 36565721, PMID 36739866, PMID 37676612, PMID 38383961
2016 (1), 2017 (1)