7 completed, 3 unknown, 2 recruiting, 1 not yet recruiting. 13 Phase 3, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 13 | Completed 7, Unknown 3, Recruiting 2, Not yet recruiting 1 |
| Phase 2 | 1 | Completed 1 |
Follow Primary Dysmenorrhea: new trials by email Literature Review of Primary Dysmenorrhea trials Research Report on Primary Dysmenorrhea
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Evaluation of the Analgesic Effect of Intramyometrial Botulinum Toxin Injection Via Hysteroscopy in Pelvic Pain Suggestive of Dysmenorrhea Xeomin, Placebo - Primary Dysmenorrhea, Chronic Pelvic Pain | Phase 3 | Recruiting | Nantes University Hospital | 222 | 2026-02-09 | 2026-07-13 |
| Study to Evaluate the Efficacy and Safety of Dexketoprofen / Butylscopolamine vs Dexketoprofen in Treatment of Primary Dysmenorrhea Dexketoprofen / Butylscopolamine in fixed dose combination tablet. (Laboratorios Silanes S.A. de C.V.), Dexketoprofen (Stadium®, Menarini Manufacturing Logistics and Services S.R.L. Conditioned by Grimann, S.A. de C.V. Distributed by: Sanfer Laboratories S.A. de C.V.) - Primary Dysmenorrhea | Phase 3 | Completed | Laboratorios Silanes S.A. de C.V. | 130 | 2025-07-02 | 2026-10-28 |
| Efficacy and Safety of CDE100 in the Treatment of Menstrual Cramp Pain Associated With Primary Dysmenorrhea CDE100 association, Buscopan® Composto association - Primary Dysmenorrhea | Phase 3 | Recruiting | EMS | 238 | 2025-06-11 | 2025-12-08 |
| Efficacy and Safety of DEH113 in the Treatment of Menstrual Cramp Pain Associated With Primary Dysmenorrhea DEH113, Placebo Comparator - Primary Dysmenorrhea | Phase 3 | Not yet recruiting | EMS | 78 | 2025-02-01 | 2024-02-22 |
| Diagnostic and Therapeutic Potential of Substance P/ NK1R Receptor in Primary Dysmenorrhea Ibuprofen and Aprepitant - Primary Dysmenorrhea | Phase 3 | Completed | Lahore Medical Research Center, LLP | 40 | 2024-03-15 | 2025-02-21 |
| Efficacy of Vitex Agnus-castus BNO 1095 (20 mg) in Women With Primary Dysmenorrhea Vitex agnus-castus BNO 1095 (20 mg), Placebo - Primary Dysmenorrhea | Phase 3 | Completed | Bionorica SE | 335 | 2023-12-12 | 2025-07-28 |
| Phase 3 Clinical Trial to Evaluate of the Efficacy and Safety of DW9801 in Patients With Primary Dysmenorrhea Pelubiprofen 45mg, Placebo - Primary Dysmenorrhea | Phase 3 | Unknown | Daewon Pharmaceutical Co., Ltd. | 120 | 2020-09-30 | 2020-09-09 |
| Preemptive Analgesia for Primary Dysmenorrhoea preemptive mefenamic acid, mefenamic acid - Primary Dysmenorrhea | Phase 2 / Phase 3 | Completed | Hanan Nabil | 84 | 2017-08-01 | 2017-12-19 |
| Low-level Light Therapy for Primary Dysmenorrhea low-level light therapy, Placebo - Primary Dysmenorrhea | Phase 3 | Completed | Pusan National University | 88 | 2011-10-01 | 2014-04-03 |
| Effect on Primary Dysmenorrhea Estradiol valerate, Dienogest (Natazia, Qlaira, BAY86-5027), Ethinyl estradiol, Levonorgestrel (Miranova), Placebo Match to SH T00658ID - Primary Dysmenorrhea | Phase 3 | Completed | Bayer | 507 | 2009-04-01 | 2015-08-24 |
| A Trial for Evaluation of Clinical Efficacy and Safety of Healing Stone Navel Belt in Patients With Primary Dysmenorrhea Healingstone navel belt - Primary Dysmenorrhea | Phase 3 | Unknown | Healingstone Co., Ltd. | 102 | 2008-08-01 | 2009-09-24 |
| Psychological Outcomes From a Study of Acupuncture Treatment on Experimentally Primary Dysmenorrhea acupuncture, Deqi, acupuncture, Non-Deqi - Primary Dysmenorrhea | Phase 3 | Unknown | Huazhong University of Science and Technology | 60 | 2008-06-01 | 2011-06-23 |
| SH T00186 in the Treatment of Primary Dysmenorrhea Drug: YAZ flex (SH T00186D), YAZ (SH T00186D) - Primary Dysmenorrhea | Phase 3 | Completed | Bayer | 223 | 2007-12-01 | 2014-10-29 |
Dysmenorrhea (2) · Pain (1)
Neurologic Manifestations (3) · Pathological Conditions, Signs and Symptoms (3) · Signs and Symptoms (3) · Menstruation Disturbances (2) · Pain (2) · Pathologic Processes (2) · Pelvic Pain (2)
Acupuncture Therapy (1) · Anti-Inflammatory Agents, Non-Steroidal (1) · Aprepitant (1) · Butylscopolammonium Bromide (1) · Estradiol (1) · Ethinyl Estradiol (1) · Ibuprofen (1) · Levonorgestrel (1) · Low-Level Light Therapy (1) · Mefenamic Acid (1) · Neurokinin-1 Receptor Antagonists (1) · dexketoprofen trometamol (1) · dienogest (1) · drospirenone and ethinyl estradiol combination (1) · incobotulinumtoxinA (1)
Bayer (2) · EMS (2) · Bionorica SE (1) · Daewon Pharmaceutical Co., Ltd. (1) · Hanan Nabil (1) · Healingstone Co., Ltd. (1) · Huazhong University of Science and Technology (1) · Laboratorios Silanes S.A. de C.V. (1) · Lahore Medical Research Center, LLP (1) · Nantes University Hospital (1) · Pusan National University (1)
Germany (3) · Austria (1) · Brazil (1) · Canada (1) · Chile (1) · China (1) · Czechia (1) · Egypt (1) · France (1) · Hungary (1) · Italy (1) · Mexico (1) · Pakistan (1) · Philippines (1) · Poland (1)
EungGi Min, MD (1) · Gi-Youn Hong, Ph.D. (1) · Hanan Nabil, MD (1) · Petra Stute, Prof. Dr. (1) · Wei Wang (1) · Yong-Il Shin, Ph.D. (1)
PMID 37523477, PMID 22454006, PMID 24713413, PMID 26797192
2008 (1), 2023 (1), 2025 (1)