14 completed, 1 unknown. 5 Phase 1, 4 Phase 2, 3 Phase 3, 3 Phase 4, 2 Not applicable.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 5 | Completed 5 |
| Phase 2 | 4 | Completed 4 |
| Phase 3 | 3 | Completed 3 |
| Phase 4 | 3 | Completed 3 |
| Not applicable | 2 | Completed 1, Unknown 1 |
Follow Mefenamic Acid: new trials by email Literature Review of Mefenamic Acid trials Research Report on Mefenamic Acid
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Vitamin E Plus Mefenamic Acid Versus Mefenamic Acid Alone for Treating Primary Dysmenorrhea in Women Mefenamic acid, Vitamin E capsule - Dysmenorrhea Primary, Vitamin E | Phase 4 | Completed | Nishtar Medical University | 60 | 2025-07-15 | 2026-03-12 |
| Management of Abnormal Uterine Bleeding Mefenamic acid 500 mg - Abnormal Uterine Bleeding | Not applicable | Completed | Egymedicalpedia | 130 | 2024-03-01 | 2025-09-03 |
| A Trial Investigating Lu AF28996 in Healthy Adult Participants Lu AF28996, Acetylsalicylic Acid, Mefenamic Acid - Healthy Participants | Phase 1 | Completed | H. Lundbeck A/S | 22 | 2024-02-27 | 2024-06-11 |
| Drug-drug Interaction Between Ciprofol and Mefanamic Acid or Valproate Mefanamic Acid, Valproate - Drug Drug Interaction | Phase 1 | Completed | Haisco Pharmaceutical Group Co., Ltd. | 41 | 2021-12-17 | 2022-07-14 |
| A Study of Soticlestat With Itraconazole and Mefenamic Acid in Healthy Adults Soticlestat, Itraconazole, Mefenamic acid - Healthy Volunteers | Phase 1 | Completed | Takeda | 28 | 2021-10-14 | 2026-09-10 |
| Drug-Drug Interaction Study to Evaluate the Effect of Inhibition of UGTs on the PK of Ecopipam and Its Active Metabolite ecopipam HCL, Mefenamic acid, Divalproex Sodium ER - Drug Interaction | Phase 1 | Completed | Emalex Biosciences Inc. | 38 | 2021-05-13 | 2021-07-22 |
| Treatment of Heavy and/or Prolonged Menstrual Bleeding Without Organic Cause combined contraceptive pills (microcept), medroxyprogesterone acetate (progest), mefenamic acid (ponstan forte) - Improve Quality of Life, Heavy Menstrual Bleeding | Phase 3 | Completed | Assiut University | 240 | 2017-11-01 | 2021-06-04 |
| Preemptive Analgesia for Primary Dysmenorrhoea preemptive mefenamic acid, mefenamic acid - Primary Dysmenorrhea | Phase 2 / Phase 3 | Completed | Hanan Nabil | 84 | 2017-08-01 | 2017-12-19 |
| Interaction Study to Evaluate the Effects of Mefenamic Acid on the Pharmacokinetics and Pharmacodynamics of Sotagliflozin in Healthy Male and Female Subjects Sotagliflozin (SAR439954), Mefenamic acid - Diabetes Mellitus | Phase 1 | Completed | Sanofi | 16 | 2017-03-14 | 2022-04-25 |
| DLBS1442 for The Treatment of Pain in Patients Suspected Endometriosis DLBS1442 100, Mefenamic acid, DLBS1442 200 - Endometrioma, Visual Analogue Pain Scale: Moderate or Severe Pain | Phase 2 / Phase 3 | Completed | Dexa Medica Group | 60 | 2015-10-01 | 2022-01-27 |
| Efficacy of Different Drugs to Control Post Root Canal Treatment Pain Paracetamol, Ibuprofen, Mefenamic Acid - Pain, Postoperative Pain | Phase 2 | Completed | University of Khartoum | 185 | 2012-08-01 | 2026-08-10 |
| The Efficacy of Ayurved Siriraj Prasaplai for Treatment Primary Dysmenorrhea Ayurved Siriraj Prasaplai with or without mefenamic acid, Placebo with or without mefenamic acid - Primary Dysmenorrhea | Phase 4 | Completed | Mahidol University | 40 | 2011-12-01 | 2013-08-27 |
| Management of Initial Bleeding/Spotting Associated With the Levonorgestrel-releasing Intrauterine System (MIRENA) Tranexamic acid, Mefenamic acid, Placebo - Uterine Hemorrhage | Phase 4 | Completed | Bayer | 187 | 2011-03-01 | 2014-11-04 |
| Efficacy of Mefenamic Acid and Hyoscine for Pain Relief During Saline Infusion Sonohysterography in Infertile Women Mefenamic acid or Hyoscine or placebo - Infertility | Not applicable | Unknown | Mahidol University | 138 | 2009-01-01 | 2010-02-02 |
| Efficacy and Safety Study of Meloxicam Versus Mefenamic Acid in Patients With Dysmenorrhea Meloxicam 7.5 mg, Meloxicam 15 mg, Mefenamic acid 500 mg - Dysmenorrhea | Phase 2 | Completed | Boehringer Ingelheim | 337 | 1998-01-01 | 2018-08-31 |
Pain (4) · Diabetes Mellitus (1) · Dysmenorrhea (1) · Endometriosis (1) · Infertility (1) · Menorrhagia (1) · Metrorrhagia (1) · Pain, Postoperative (1) · Uterine Hemorrhage (1)
Mahidol University (2) · Assiut University (1) · Bayer (1) · Boehringer Ingelheim (1) · Dexa Medica Group (1) · Egymedicalpedia (1) · Emalex Biosciences Inc. (1) · H. Lundbeck A/S (1) · Haisco Pharmaceutical Group Co., Ltd. (1) · Hanan Nabil (1) · Nishtar Medical University (1) · Sanofi (1) · Takeda (1) · University of Khartoum (1)
Egypt (3) · United States (3) · Thailand (2) · China (1) · Denmark (1) · France (1) · Indonesia (1) · Ireland (1) · Norway (1) · Pakistan (1) · Sudan (1)
Hanan Nabil, MD (1) · Kanadi Sumapraja, SpOG(K), MD (1) · Neamat Abubakr, BDS,MDSc,PhD (1) · Omnia Bakar Bakar, Lecturer (1) · Shazia S Assistant Professor, FCPS (1) · Singpetch Suksompong, Doctor (1) · Thanyarat Wongwananuruk, MD. (1)
PMID 10613619, PMID 12148679, PMID 15230906, PMID 17437870, PMID 18498882, PMID 23635728, PMID 27080115, PMID 9594474