2 completed, 2 recruiting, 1 not yet recruiting. 5 Phase 2, 2 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 5 | Completed 2, Recruiting 2, Not yet recruiting 1 |
| Phase 1 | 2 | Not yet recruiting 1, Recruiting 1 |
Follow Presbycusis: new trials by email Literature Review of Presbycusis trials Research Report on Presbycusis
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| First In Human Randomised Trial of Rincell-1 in Adults With a Cochlear Implant Otic neural progenitors, cochlear implantation - Sensorineural Hearing Loss, Presbyacusis | Phase 1 / Phase 2 | Not yet recruiting | Rinri Therapeutics | 20 | 2027-09-01 | 2026-10-01 |
| First Clinical Study to Evaluate Safety, Tolerability & PK of DX243 in Healthy Volunteers and Patients With Hearing Loss DX243, Placebo - Age-related Hearing Loss | Phase 2 | Recruiting | Dendrogenix | 24 | 2026-05-13 | 2026-06-10 |
| A Treatment for a Form of Age-Related Central Auditory Processing Disorder Consisting of Clemastine Fumarate Plus Engineered Sound Clemastine Fumarate Combined With Engineered Sound, Clemastine Fumarate Combined With Pink Noise, Placebo Drug With Engineered Sound - Central Auditory Processing Disorder, Hearing Impaired (Partially) | Phase 1 / Phase 2 | Recruiting | University of Colorado, Denver | 344 | 2025-03-31 | 2026-04-30 |
| Efficacy and Safety of Liuwei Dihuang Pill Versus Placebo in Presbycusis With Shen (Kidney)-Yin Deficiency Liuwei Dihuang Pill (marketed product in China), Liuwei Dihuang Pill（placebo ） - Presbycusis, Age-related Hearing Loss | Phase 2 | Completed | Shanghai Jiao Tong University School of Medicine | 120 | 2022-01-25 | 2026-01-07 |
| Efficacy and Safety of AUT00063 Versus Placebo in Age-Related Hearing Loss AUT00063, Placebo - Age-Related Hearing Loss | Phase 2 | Completed | Autifony Therapeutics Limited | 78 | 2015-01-01 | 2018-08-09 |
Hearing Disorders (2) · Hearing Loss (2) · Hearing Loss, Sensorineural (2) · Auditory Diseases, Central (1) · Auditory neuropathy (1) · Deafness (1) · Hearing Loss, Hidden (1) · Hearing Loss, Noise-Induced (1) · Language Development Disorders (1) · Retrocochlear Diseases (1)
Ear Diseases (5) · Nervous System Diseases (5) · Neurologic Manifestations (5) · Otorhinolaryngologic Diseases (5) · Pathological Conditions, Signs and Symptoms (5) · Sensation Disorders (5) · Signs and Symptoms (5) · Hearing Disorders (3) · Hearing Loss (3) · Hearing Loss, Sensorineural (3) · Brain Diseases (1) · Central Nervous System Diseases (1) · Communication Disorders (1) · Language Disorders (1) · Neurobehavioral Manifestations (1)
AUT00063 (1) · Clemastine (1) · Cochlear Implantation (1) · Liuwei Dihuang Decoction (1) · Placebo Effect (1)
Autifony Therapeutics Limited (1) · Dendrogenix (1) · Rinri Therapeutics (1) · Shanghai Jiao Tong University School of Medicine (1) · University of Colorado, Denver (1)
United States (2) · Belgium (1) · China (1) · United Kingdom (1)
Achim Klug, PhD (1) · Douglas Hartley (1) · Hongsheng Tan, Doctor (1) · Jianning Zhang, Doctor (1) · Jianrong Shi, Doctor (1) · Ping Huang, Doctor (1) · Robert Frisina, PhD (1) · Samuel A Budoff, PhD, MS (1)
2023 (1)