9 completed, 3 unknown, 1 recruiting, 1 withdrawn. 5 Phase 2, 3 Phase 1, 3 Phase 3, 1 Not applicable, 1 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 5 | Completed 3, Unknown 1, Withdrawn 1 |
| Phase 1 | 3 | Completed 2, Unknown 1 |
| Phase 3 | 3 | Completed 3 |
| Not applicable | 1 | Completed 1 |
| Phase 4 | 1 | Completed 1 |
Follow Posterior Uveitis: new trials by email Literature Review of Posterior Uveitis trials Research Report on Posterior Uveitis
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Intravitreal Sirolimus as Therapeutic Approach to Uveitis Intravitreal injection 440mcg, Intravitreal injection of sirolimus 880mcg - Uveitis, Intermediate Uveitis | Phase 2 | Withdrawn | Stanford University | 2022-09-01 | 2023-10-26 | |
| Pilot Project: The Amplicon and Metatranscriptomic Study of Intra and Extra Intestinal Microbiome in Non-infectious Uveitis Disease Autoimmune Uveitis, Behçet Disease | Unknown | Fakultas Kedokteran Universitas Indonesia | 10 | 2019-11-01 | 2019-10-17 | |
| Dexamethasone Intravitreal Implant (Ozurdex®) for Recurrent Vogt-Koyanagi-Harada (VKH) Disease Posterior Uveitis Dexamethasone Ophthalmic implant - Posterior Uveitis | Completed | Benha University | 16 | 2017-01-01 | 2019-11-26 | |
| Study of H.P. ACTHAR Subcutaneous Gelatin (Gel)(Highly Purified Gel Injection) in Uveitis Patients H.P. ACTHAR SUBCUTANEOUS GEL INJECTION - Uveitis, Anterior Uveitis | Phase 4 | Completed | Tampa Bay Uveitis Center, LLC | 6 | 2016-06-30 | 2018-07-02 |
| Safety and Efficacy Study of a FAI Insert in Subjects With Chronic Non-infectious Posterior Uveitis Sham Injection, FAI Insert - Posterior Uveitis, Intermediate Uveitis | Phase 3 | Completed | EyePoint Pharmaceuticals, Inc. | 153 | 2015-06-02 | 2020-07-21 |
| Study of the Safety, Tolerability, and Bioactivity of Tocilizumab On Patients With Non-infectious UVEITIS: The STOP-UVEITIS Study Tocilizumab - Intermediate Uveitis, Posterior Uveitis | Phase 1 / Phase 2 | Unknown | University of Nebraska | 36 | 2013-03-01 | 2017-04-28 |
| Safety Study of Suprachoroidal Triamcinolone Acetonide Via Microneedle to Treat Uveitis triamcinolone acetonide (Triesence®) - Uveitis, Intermediate Uveitis | Phase 1 / Phase 2 | Completed | Clearside Biomedical, Inc. | 11 | 2013-02-01 | 2021-02-21 |
| Sirolimus as Therapeutic Approach to Uveitis Sirolimus (rapamycin) - Uveitis, Intermediate Uveitis | Phase 1 | Completed | Johns Hopkins University | 30 | 2009-07-01 | 2018-08-20 |
| Safety, Tolerability, and Efficacy of AEB071 in the Treatment of Uveitis AEB071 - Uveitis, Posterior Uveitis | Phase 2 | Completed | Novartis | 13 | 2008-07-01 | 2020-12-22 |
| Retisert and Cataract Surgery in Patients With Severe Uveitis Retisert (fluocinolone acetonide implant) - Intermediate Uveitis, Posterior Uveitis | Not applicable | Completed | Duke University | 21 | 2006-09-01 | 2014-09-03 |
| Quality of Life and Visual Function in Uveitis Patients Anterior Uveitis, Posterior Uveitis | Unknown | The New York Eye & Ear Infirmary | 50 | 2006-06-01 | 2006-12-05 | |
| A Study of the Safety and Efficacy of a New Treatment for Non-Infectious Intermediate or Posterior Uveitis Dexamethasone, dexamethasone, Sham injection - Intermediate Uveitis, Posterior Uveitis | Phase 2 / Phase 3 | Completed | Allergan | 229 | 2006-05-01 | 2011-04-14 |
| Birdshot Chorioretinopathy : Prospective Follow-up and Immunogenetic Studies(CO-BIRD) Observational study - Birdshot Chorioretinopathy, Posterior Uveitis | Recruiting | Assistance Publique - Hôpitaux de Paris | 600 | 2004-11-02 | 2026-03-04 | |
| Interferon-alpha2a Versus Cyclosporin A for Severe Ocular Behcet's Disease (INCYTOB) Cyclosporin A, Interferon-alpha2a - Behcet's Disease, Panuveitis | Phase 3 | Completed | University Hospital Tuebingen | 37 | 2004-11-01 | 2018-05-17 |
Uveitis, Posterior (14) · Uveitis, Intermediate (9) · Panuveitis (7) · Uveitis (6) · Behcet Syndrome (2) · Uveitis, Anterior (2) · Birdshot Chorioretinopathy (1) · Choroidal Effusions (1) · Giant Cell Arteritis (1) · Inflammation (1) · Macular Edema (1) · Ophthalmia, Sympathetic (1) · Retinal Vasculitis (1) · Scleritis (1) · Uveomeningoencephalitic Syndrome (1)
Eye Diseases (14) · Uveal Diseases (14) · Uveitis (8) · Panuveitis (7) · Autoimmune Diseases (3) · Cardiovascular Diseases (3) · Immune System Diseases (3) · Retinal Diseases (3) · Skin Diseases (3) · Skin Diseases, Vascular (3) · Skin and Connective Tissue Diseases (3) · Vascular Diseases (3) · Vasculitis (3) · Autoimmune Diseases of the Nervous System (2) · Choroid Diseases (2)
salicylhydroxamic acid (2) · Adrenal Cortex Hormones (1) · Adrenocorticotropic Hormone (1) · Calcium Dobesilate (1) · Contraceptives, Oral (1) · Cyclosporine (1) · Dexamethasone (1) · Fluocinolone Acetonide (1) · Interferon alpha-2 (1) · Intravitreal Injections (1) · Observation (1) · Sirolimus (1) · Triamcinolone (1) · Triamcinolone Acetonide (1) · sotrastaurin (1)
Allergan (1) · Assistance Publique - Hôpitaux de Paris (1) · Benha University (1) · Clearside Biomedical, Inc. (1) · Duke University (1) · EyePoint Pharmaceuticals, Inc. (1) · Fakultas Kedokteran Universitas Indonesia (1) · Johns Hopkins University (1) · Novartis (1) · Stanford University (1) · Tampa Bay Uveitis Center, LLC (1) · The New York Eye & Ear Infirmary (1) · University Hospital Tuebingen (1) · University of Nebraska (1)
United States (9) · France (2) · Germany (2) · India (2) · Australia (1) · Austria (1) · Brazil (1) · Canada (1) · Czechia (1) · Greece (1) · Indonesia (1) · Israel (1) · Poland (1) · Portugal (1) · South Africa (1)
Quan D Nguyen, MD, MSc (3) · C. Michael Samson, MD (1) · Flavio Leonin Jr., MD (1) · Glenn J Jaffe, MD (1) · Grace L Clarke (1) · Ina Koetter, MD (1) · Ratna Sitompul, Professor (1) · Tarek Elhamaky (1) · Thomas Ciulla, MD (1)
PMID 18639220, PMID 21220619, PMID 23411886, PMID 23761087, PMID 25918559, PMID 27980877, PMID 33042579, PMID 37172782, PMID 37204866, PMID 38027419, PMID 39250617, PMID 40010761