7 completed, 3 recruiting, 2 not yet recruiting, 2 unknown. 8 Not applicable, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 8 | Completed 4, Recruiting 2, Enrolling by invitation 1, Terminated 1 |
| Phase 3 | 1 | Active not recruiting 1 |
Follow Post-Intensive Care Syndrome: new trials by email Literature Review of Post-Intensive Care Syndrome trials Research Report on Post-Intensive Care Syndrome
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Patients With Long-stay at ICU: Factors and Evaluation - Feasibility Study Frailty, Delirium Confusional State | Not yet recruiting | Uppsala University | 300 | 2026-10-01 | 2026-10-01 | |
| PICS Clinic Attendance and Recovery Engagement (PICS-CARE) Post-intensive Care Syndrome | Recruiting | Charite University, Berlin, Germany | 2500 | 2026-02-10 | 2026-02-12 | |
| Post-ICU Syndrome Over Time in Patients With Respiratory Failure Questionnaire and Physical Exam, EuroQol 5-Dimension 3-Level, EuroQol Visual Analogue Scale (EQ-VAS) - Post-Intensive Care Syndrome, Quality of Life | Not yet recruiting | Hospital Universitario de Gran Canaria Doctor Negrín | 90 | 2025-10-01 | 2025-09-08 | |
| Application of Large Language Models Techniques to Post-ICU Syndrome Management in Critically Ill Patients: A Fully Longitudinal Mixed Study Routine Care, Health Promotion Model-Based Optimized Program, LLM-Enhanced Optimized Program - Post-Intensive Care Syndrome | Not applicable | Enrolling by invitation | The Affiliated Hospital Of Guizhou Medical University | 90 | 2025-06-01 | 2025-08-26 |
| Improving Outcomes in PICS With Home-Based Program of Rehabilitation and Health Coaching Home-based Physical Rehabilitation, Health Coaching - Post-Intensive Care Syndrome | Not applicable | Completed | Mayo Clinic | 78 | 2024-05-08 | 2026-07-22 |
| Telehealth-enhanced Patient-oriented Recovery Trajectory After Intensive Care Telemedicine ICU Recovery Clinic Visit - Post-intensive Care Syndrome | Not applicable | Recruiting | Vanderbilt University | 202 | 2024-03-13 | 2026-07-09 |
| Pilot Study of a Multidisciplinary Intervention in ICU Survivors at Risk for Psychological or Physical Morbidity Case-manager led multidisciplinary follow-up after intensive care - Post-Intensive Care Syndrome, Depressive Symptoms | Not applicable | Terminated | Region Stockholm | 41 | 2024-02-01 | 2026-08-13 |
| Hand and Arm Rehabilitation Using VR VR training for arm and hand rehabilitation - Post-Intensive Care Syndrome, ICU Acquired Weakness | Not applicable | Recruiting | Frisius Medisch Centrum | 108 | 2024-01-15 | 2024-04-18 |
| Pilot Testing PICTURE-THIS PICTURE-THIS, Enhanced Usual Care, Run-In Phase - Post-intensive Care Syndrome, Transitional Care | Not applicable | Completed | University of Pittsburgh | 42 | 2023-08-09 | 2025-12-18 |
| Neurological Blood-based Biomarkers and Cognitive Disorders in Critically Ill Survivors. Blood analysis, Cognitive tests - Intensive Care Unit Syndrome, Post-intensive Care Syndrome | Unknown | University of Liege | 30 | 2023-06-23 | 2023-07-20 | |
| A Pooled Analysis of Long-Term Outcomes After Inhaled Isoflurane Via the Sedaconda ACD-S Compared to Intravenous Propofol Inhaled isoflurane administered by Sedaconda ACD-S, Intravenous infusion of propofol - Post-Intensive Care Syndrome, Sedation | Phase 3 | Active not recruiting | Sedana Medical | 312 | 2022-04-22 | 2025-02-05 |
| Functional Capacity in Survivors of COVID-19 Related ARDS Covid19, Functional Capacity | Unknown | Koç University | 15 | 2021-07-01 | 2021-07-07 | |
| Clinical and Functional Characteristics of Patients Admitted for Severe COVID-19 Pneumonia Health-Related Quality of Life (HRQoL) with EQ-5D-3L - Post-intensive Care Syndrome, COVID-19 | Completed | Hospital Nacional Profesor Alejandro Posadas | 51 | 2020-06-01 | 2026-04-17 | |
| Family and Patient Outcomes After Pediatric Intensive Care (FOREVER) Hospital diaries - Post-Intensive Care Syndrome, Anxiety | Not applicable | Completed | D'Or Institute for Research and Education | 431 | 2019-12-20 | 2025-12-24 |
| Quality of Life and Functional Capacity in Post Intensive Care Unit Observational Quality of life and functional capacity - Post-intensive Care Syndrome | Completed | Sanatorio Anchorena San Martin | 101 | 2019-08-01 | 2022-02-23 | |
| Collaborative Assessment of ICU Recovery Needs Patient, Carer, and Clinician Interviews - Post-Intensive Care Syndrome | Completed | Vanderbilt University Medical Center | 66 | 2018-04-03 | 2020-02-18 | |
| Mobile Critical Care Recovery Program for Acute Respiratory Failure Survivors Mobile Critical Care Program, Attention Control - Acute Respiratory Failure, Post-Intensive Care Syndrome | Not applicable | Completed | Indiana University | 503 | 2017-03-01 | 2024-06-24 |
postintensive care syndrome (17) · Anxiety Disorders (2) · COVID-19 (2) · Depression (2) · Stress Disorders, Post-Traumatic (2) · Cognitive Dysfunction (1) · Confusion (1) · Fatigue (1) · Frailty (1) · Motor Activity (1) · Patient Satisfaction (1) · Respiratory Distress Syndrome (1)
Mental Disorders (4) · Behavior (3) · Behavioral Symptoms (2) · Coronaviridae Infections (2) · Coronavirus Infections (2) · Infections (2) · Lung Diseases (2) · Nidovirales Infections (2) · Pneumonia (2) · Pneumonia, Viral (2) · RNA Virus Infections (2) · Respiratory Tract Diseases (2) · Respiratory Tract Infections (2) · Stress Disorders, Traumatic (2) · Trauma and Stressor Related Disorders (2)
Caregivers (1) · Hematologic Tests (1) · Neuropsychological Tests (1) · Physical Examination (1) · Visual Analog Scale (1)
Charite University, Berlin, Germany (1) · D'Or Institute for Research and Education (1) · Frisius Medisch Centrum (1) · Hospital Nacional Profesor Alejandro Posadas (1) · Hospital Universitario de Gran Canaria Doctor Negrín (1) · Indiana University (1) · Koç University (1) · Mayo Clinic (1) · Region Stockholm (1) · Sanatorio Anchorena San Martin (1) · Sedana Medical (1) · The Affiliated Hospital Of Guizhou Medical University (1) · University of Liege (1) · University of Pittsburgh (1) · Uppsala University (1)
United States (6) · Argentina (2) · Sweden (2) · Australia (1) · Belgium (1) · Brazil (1) · China (1) · Germany (1) · Netherlands (1) · Spain (1) · Turkey (Türkiye) (1)
Anna Milton (1) · Babar A Khan, MD, MS (1) · Carla M Sevin, M.D. (1) · Claudia Spies, MD, Prof. (1) · Fernanda Lima-Setta (1) · Ing-Marie Larsson, RN, PhD (1) · Leanne M Boehm, PhD (1) · Leslie P Scheunemann, MD MPH (1) · Lise Beumeler, PhD (1) · Ozden Ozyemisci Taskiran, Prof (1) · Peter Sackey, MD, PhD (1) · Rodrigo Cartin-Ceba, MD (1)
PMID 21946660, PMID 26105747, PMID 29415760, PMID 31704795, PMID 32442308, PMID 32644129, PMID 32900518, PMID 32988390, PMID 35184214, PMID 37659250, PMID 38289602, PMID 39526840, PMID 41938652
R01AG077644 (1)