4 completed, 4 recruiting, 1 active not recruiting, 1 unknown. 1 Not applicable, 1 Phase 2, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 1 | Active not recruiting 1 |
| Phase 2 | 1 | Completed 1 |
| Phase 3 | 1 | Recruiting 1 |
Follow Pleuropulmonary blastoma: new trials by email Literature Review of Pleuropulmonary blastoma trials Research Report on Pleuropulmonary blastoma
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Testing a Standardized Approach to Surgery and Chemotherapy for Type I Pleuropulmonary Blastoma or the Addition of an Anti-cancer Drug, Topotecan, to the Usual Treatment for Types II and III Pleuropulmonary Blastoma Biospecimen Collection, Bone Scan, Computed Tomography - Pleuropulmonary Blastoma | Phase 3 | Recruiting | Children's Oncology Group | 110 | 2025-03-21 | 2026-08-25 |
| An International Study on Pediatric Patients With Rare Tumors. Paraganglioma/ Phaeochromocytoma, Melanoma and Other Malignant Neoplasms of Skin | Recruiting | Azienda Ospedaliera di Padova | 6250 | 2025-01-25 | 2025-07-18 | |
| Review of the Paediatric Pleuropulmonary Blastoma French Series PPB - Pleuropulmonary Blastoma | Completed | Rennes University Hospital | 41 | 2017-01-09 | 2020-08-12 | |
| International PPB/DICER1 Registry Pleuropulmonary Blastoma, Sertoli-Leydig Cell Tumor | Recruiting | Children's Hospitals and Clinics of Minnesota | 3400 | 2016-12-06 | 2025-01-30 | |
| Congenital Lung Anomalies (CLA) Swiss Database Malformations resection - Congenital Lung Malformation, Congenital Lung Cyst | Unknown | University Hospital, Geneva | 100 | 2016-04-01 | 2020-04-16 | |
| Lorvotuzumab Mertansine in Treating Younger Patients With Relapsed or Refractory Wilms Tumor, Rhabdomyosarcoma, Neuroblastoma, Pleuropulmonary Blastoma, Malignant Peripheral Nerve Sheath Tumor, or Synovial Sarcoma Laboratory Biomarker Analysis, Lorvotuzumab Mertansine, Pharmacological Study - Pleuropulmonary Blastoma, Recurrent Malignant Peripheral Nerve Sheath Tumor | Phase 2 | Completed | Children's Oncology Group | 62 | 2015-10-12 | 2022-01-13 |
| Gene Mutation in Samples From Young Patients With Pleuropulmonary Blastoma Syndrome at Risk for Developing Cancer DNA analysis, cytogenetic analysis, gene expression analysis - Brain and Central Nervous System Tumors, Hereditary Wilms Tumor | Completed | Children's Oncology Group | 31 | 2011-05-01 | 2016-07-11 | |
| DICER1-related Pleuropulmonary Blastoma Cancer Predisposition Syndrome: A Natural History Study Pleuropulmonary Blastoma, Cystic Nephroma | Recruiting | National Cancer Institute (NCI) | 1500 | 2011-02-13 | 2026-10-16 | |
| International Pleuropulmonary Blastoma (PPB) Treatment and Biology Registry Vincristine, Dactinomycin, Cyclophosphamide - Pleuropulmonary Blastoma | Not applicable | Active not recruiting | Children's Hospitals and Clinics of Minnesota | 156 | 2009-12-22 | 2024-08-21 |
| Elucidating the Genetic Basis of the Pleuropulmonary Blastoma (PPB) Familial Cancer Syndrome Pleuropulmonary Blastoma, Cystic Nephroma | Completed | Ashley Hill | 1247 | 2005-03-01 | 2023-03-01 |
Neuroblastoma (3) · Thyroid Neoplasms (3) · Wilms Tumor (3) · Pinealoma (2) · Pituitary Neoplasms (2) · Sarcoma (2) · Sertoli-Leydig Cell Tumor (2) · Adrenal Cortex Neoplasms (1) · Central Nervous System Neoplasms (1) · Cystic Adenomatoid Malformation of Lung, Congenital (1) · Cystic Disease Of Lung (1) · Disease (1) · Esthesioneuroblastoma, Olfactory (1) · Gastrointestinal Stromal Tumors (1)
Neoplasms (6) · Neoplasms by Site (6) · Neoplasms by Histologic Type (5) · Neoplasms, Connective and Soft Tissue (5) · Neoplasms, Germ Cell and Embryonal (5) · Neoplasms, Glandular and Epithelial (5) · Neoplasms, Nerve Tissue (5) · Neoplasms, Neuroepithelial (5) · Nervous System Diseases (5) · Neuroectodermal Tumors (5) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (4) · Endocrine Gland Neoplasms (4) · Endocrine System Diseases (4) · Female Urogenital Diseases (4) · Female Urogenital Diseases and Pregnancy Complications (4)
Cyclophosphamide (2) · Dactinomycin (2) · Doxorubicin (2) · Ifosfamide (2) · Vincristine (2) · Ado-Trastuzumab Emtansine (1) · Amplified Fragment Length Polymorphism Analysis (1) · Cytogenetic Analysis (1) · Dexrazoxane (1) · Gene Expression Profiling (1) · Gene Rearrangement (1) · High-Energy Shock Waves (1) · Magnetic Resonance Spectroscopy (1) · Observation (1) · Polymerase Chain Reaction (1)
Children's Oncology Group (3) · Children's Hospitals and Clinics of Minnesota (2) · Ashley Hill (1) · Azienda Ospedaliera di Padova (1) · National Cancer Institute (NCI) (1) · Rennes University Hospital (1) · University Hospital, Geneva (1)
United States (6) · Canada (1) · France (1) · Italy (1) · Switzerland (1)
Kris Ann P Schultz, MD (2) · D. Ashley Hill, MD (1) · Dana A. Hill, MD (1) · Douglas R Stewart, M.D. (1) · Gianni Bisogno, MD (1) · Isabelle Andrieu Vidal, MD PhD (1) · James I Geller (1) · Kris Ann P Schultz (1) · Kris Ann Schultz, MD (1)
PMID 19556464, PMID 25209242, PMID 29343557, PMID 33570641, PMID 24481001, PMID 24761742, PMID 24821309, PMID 24909177, PMID 25118636, PMID 25356068, PMID 26555935, PMID 26925222, PMID 27441995, PMID 28323992, PMID 28674120, PMID 28748527, PMID 29037807, PMID 30178239, PMID 30339877, PMID 30672147, PMID 30677214, PMID 30715996, PMID 30824630, PMID 31296931, PMID 31820118, PMID 31838154, PMID 31952842, PMID 32291395, PMID 32415267, PMID 33119505, PMID 33484847, PMID 33630087, PMID 33637876, PMID 33782093, PMID 33875804
U10CA180886 (2)