36 completed, 20 unknown, 2 recruiting, 1 active not recruiting. 44 Not applicable, 6 Phase 4, 4 Phase 2, 3 Phase 3, 1 Early Phase 1.
Follow Photoaging: new trials by email Literature Review of Photoaging trials Research Report on Photoaging
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Driving Time and Facial Skin Hydration Asymmetry in Florida Drivers BT-Analyze bioimpedance skin hydration measurement - Skin Diseases, Photoaging | Recruiting | IAS Skin Care | 80 | 2026-10-05 | 2026-10-13 | |
| Study of RRS® HA Long Lasting for Improving Facial Wrinkles and Skin Quality RRS® HA Long Lasting - Photoaged Facial Skin, Photoaging | Not applicable | Recruiting | Skin Tech Pharma Group S.L.U. | 207 | 2026-04-26 | 2026-09-15 |
| AI-Personalized Skincare Regimen for Facial Photoaging in Women AI-personalized skin longevity regimen - Photoaging, Skin Aging | Not applicable | Completed | MDalgorithms Inc. | 43 | 2025-09-30 | 2026-10-19 |
| Randomised Controlled Trial of an Antioxidant and Sunscreen Combination Cream for Reducing DNA Damage in Human Skin Antioxidant + Sunscreen Cream, Placebo cream - Photoaging, Photodamage | Not applicable | Completed | Klira Skin | 52 | 2025-03-01 | 2025-12-24 |
| Platelet Rich Fibrin Versus Platelet Rich Plasma for Microneedling Treatment of Facial Photoaging platelet-rich fibin, platelet-rich palsma - Photoaging | Not applicable | Unknown | Chang Gung Memorial Hospital | 30 | 2024-06-01 | 2024-06-11 |
| Investigating Age Dependence of Fibroblast and Extracellular Matrix Responses to Cross-linked Hyaluronic Acid Filler in Human Skin Restylane-L, Vehicle - Photoaging | Not applicable | Active not recruiting | University of Michigan | 15 | 2024-05-09 | 2026-08-17 |
| Evaluation of the Effects of a Biostimulator and Dermal Fillers for Cheek Augmentation and Contour Deficiencies Sculptra treatment, Restylane Treatment - Photoaging, Weight Loss | Not applicable | Completed | Galderma R&D | 41 | 2024-02-19 | 2026-04-15 |
| RFMN in Combination With 1927 nm Thulium Laser for Treating Photoaged Skin radiofrequency microneedling combined with 1927 nm thulium laser, radiofrequency microneedling monotherapy - Photoaging | Not applicable | Unknown | Universitätsklinikum Hamburg-Eppendorf | 35 | 2023-12-15 | 2024-05-21 |
| Effects of an Oral Herbal Supplement on Skin Aging, Hydration, and Elasticity Oral herbal supplement, Oral placebo supplement - Photoaging | Not applicable | Unknown | Integrative Skin Science and Research | 36 | 2023-12-01 | 2023-11-24 |
| A 56-day Clinical Study on Facial Skin Rejuvenation Fractional picosecond laser treatment followed by daily use of formulations containing MLYAAT-1002®., Fractional picosecond laser treatment followed by daily use of formulations without MLYAAT-1002® - Skin Manifestations, Wrinkle | Not applicable | Completed | Botanee Group Co., Ltd. | 24 | 2023-11-18 | 2024-08-16 |
| Trial Evaluating Both Tolerability and Improvement for Signs of Facial Photoaging, Discoloration, and Texture in Adult Females of All Skin Types by Combining a Placebo Moisturizer and Non-ablative Laser. LaseMD Laser, Sciton Laser, Phyto A+ Brightening Treatment - Photoaging | Phase 4 | Completed | Austin Institute for Clinical Research | 38 | 2023-11-14 | 2024-10-24 |
| The Effects of Zinc Di-(Dibutyryl Lisinate) on Skin Health and the Skin Microbiome in Photoaged Skin Topical Vehicle + Zinc Di-(dibutyryl lisinate), Topical Vehicle - Photoaging | Not applicable | Unknown | Integrative Skin Science and Research | 46 | 2023-10-15 | 2023-10-24 |
| Evaluating Procedure Pairing of a Post-Procedure Cream Versus a Comparator in Patients Treated With Fractional Ablative CO2 Laser for Facial Rejuvenation Fractional Ablative CO2 Laser, Facial Cleanser, Facial Moisturizer - Photoaging, Wrinkle | Not applicable | Completed | Revision Skincare | 23 | 2023-10-03 | 2025-08-03 |
| Oral Supplementation of Astaxanthin on Skin Photoaging, Hydration and Elasticity Astaxanthin 6 mg daily, Placebo - Photoaging | Not applicable | Unknown | Integrative Skin Science and Research | 24 | 2023-07-24 | 2023-07-25 |
| RECELL to Promote Healing Following Carbon Dioxide (CO2) Laser Treatment in Cosmetic Patients ReCell - Carbon Dioxide Laser, Photoaging | Phase 4 | Terminated | Wake Forest University Health Sciences | 1 | 2023-03-22 | 2024-08-09 |
| TCA 15% Chemical Peel for Improvement in Hand Lentigines 15% Trichloroacetic acid + 3% glycolic acid - Photoaging, Lentigo | Phase 4 | Completed | Main Line Center for Laser Surgery | 20 | 2023-03-15 | 2025-03-17 |
| Safety and Efficacy Evaluation of the Mosaic Ultra Device Mosaic - Skin Texture Disorder, Photoaging | Not applicable | Unknown | CynosureLutronic | 200 | 2023-02-21 | 2023-11-07 |
| Effects of Stabilized Retinaldehyde on Aging Skin: A Split-Face Study Stabilized retinaldehyde 0.1%, Stabilized retinaldehyde 0.05% - Skin Aging, Photoaging | Not applicable | Completed | Medical University of Silesia | 56 | 2023-02-01 | 2026-04-03 |
| Double-Blind Study Determining the Efficacy of CannaXR in Decreasing UVA Premutagenic and Photoaging Markers In a double-blinded fashion, 250 mg CANNAXR cream, Topical VEHICLE cream - Photoaging | Not applicable | Completed | MINO Labs, LLC | 20 | 2023-01-15 | 2025-05-08 |
| A Twelve Week Clinical Study to Evaluate the Efficacy and Tolerability of a Sunscreen Moisturizer SPF 50+ Sunscreen Moisturizer, Gentle Cleansing Lotion, Facial Moisturizer - Anti-aging, Photoaging | Not applicable | Completed | Revision Skincare | 36 | 2022-11-09 | 2023-11-28 |
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Cutis Laxa (3) · Acne Vulgaris (2) · Keratosis, Actinic (2) · Alopecia (1) · Atrophy (1) · Carcinogenesis (1) · Cicatrix (1) · Dermatitis (1) · Facial Asymmetry (1) · Facial Hemiatrophy (1) · Hyperpigmentation (1) · Lentigo (1) · Melanosis (1) · Metabolic Diseases (1) · Pigmentation Disorders (1)
Skin and Connective Tissue Diseases (11) · Skin Diseases (10) · Pathological Conditions, Signs and Symptoms (7) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (3) · Connective Tissue Diseases (3) · Genetic Diseases, Inborn (3) · Pathologic Processes (3) · Pathological Conditions, Anatomical (3) · Pigmentation Disorders (3) · Signs and Symptoms (3) · Skin Diseases, Genetic (3) · Acneiform Eruptions (2) · Hyperpigmentation (2) · Keratosis (2) · Neoplasms (2)
Sunscreening Agents (6) · Tretinoin (5) · Adapalene (2) · Botulinum Toxins (2) · Botulinum Toxins, Type A (2) · Isotretinoin (2) · Retinoids (2) · cetyl alcohol, propylene glycol, sodium lauryl sulfate non-lipid cleansing lotion (2) · glycolic acid (2) · Antioxidants (1) · Chemexfoliation (1) · Cosmetics (1) · Dietary Supplements (1) · Extracorporeal Shockwave Therapy (1) · Food (1)
Revision Skincare (9) · Integrative Skin Science and Research (7) · Federal University of São Paulo (3) · Galderma R&D (2) · Main Line Center for Laser Surgery (2) · Adipeau Inc. (1) · Austin Institute for Clinical Research (1) · Bausch Health Americas, Inc. (1) · Botanee Group Co., Ltd. (1) · CES University (1) · Chang Gung Memorial Hospital (1) · Cutera Inc. (1) · Cynosure, Inc. (1) · CynosureLutronic (1) · DermTech (1)
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