5 completed, 1 unknown. 3 Not applicable, 3 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 3 | Completed 2, Unknown 1 |
| Phase 1 | 3 | Completed 3 |
Follow Pharmacodynamic: new trials by email Literature Review of Pharmacodynamic trials Research Report on Pharmacodynamic
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Evaluation of Vamorolone Mineralocorticoid Receptor Antagonism in Healthy Subjects Vamorolone, Eplerenone, Fludrocortisone - Pharmacodynamic | Phase 1 | Completed | Santhera Pharmaceuticals | 30 | 2024-06-05 | 2025-09-11 |
| Population Pharmacokinetics/Pharmacodynamics of Carbapenems in Febrile Neutropenia Patients Dose prediction using population pharmacokinetic models - Febrile Neutropenia, Pharmacokinetics | Not applicable | Unknown | The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School | 100 | 2022-12-31 | 2022-12-27 |
| Pharmacodynamic Evaluation of Intranasal Nalmefene Nalmefene hydrochloride, Naloxone hydrochloride - Pharmacodynamic | Phase 1 | Completed | Opiant Pharmaceuticals Inc | 84 | 2021-03-30 | 2025-07-14 |
| Clinical Outcome Study of High-dose Meropenem in Sepsis and Septic Shock Patients Meropenem standard dose, Meropenem high dose - Sepsis, Septic Shock | Not applicable | Completed | Mahidol University | 76 | 2017-11-27 | 2019-03-12 |
| To Investigate PK and PD of CJ-12420, Clarithromycin, Amoxicillin After Multiple Dose Administration CLR 500mg, CJ-12420 100mg, CJ-12420 50mg - Drug Interaction, Pharmacokinetic | Phase 1 | Completed | HK inno.N Corporation | 60 | 2016-05-01 | 2017-05-12 |
| Study of the Ability of Betaine Hydrochloride to Increase Stomach Acid in Healthy Volunteers betaine hydrochloride, Rabeprazole - Pharmacodynamic | Not applicable | Completed | University of California, San Francisco | 6 | 2011-03-01 | 2013-07-02 |
Critical Illness (1) · Febrile Neutropenia (1) · Multiple Organ Failure (1) · Sepsis (1) · Shock, Septic (1)
Agranulocytosis (1) · Cytopenia (1) · Disease Attributes (1) · Hematologic Diseases (1) · Hemic and Lymphatic Diseases (1) · Infections (1) · Inflammation (1) · Leukocyte Disorders (1) · Leukopenia (1) · Neutropenia (1) · Pathologic Processes (1) · Pathological Conditions, Signs and Symptoms (1) · Shock (1) · Systemic Inflammatory Response Syndrome (1)
Amoxicillin (1) · Betaine (1) · Clarithromycin (1) · Drugs, Investigational (1) · Eplerenone (1) · Fludrocortisone (1) · Meropenem (1) · Naloxone (1) · Pantoprazole (1) · Rabeprazole (1) · VBP15 compound (1) · nalmefene (1)
HK inno.N Corporation (1) · Mahidol University (1) · Opiant Pharmaceuticals Inc (1) · Santhera Pharmaceuticals (1) · The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School (1) · University of California, San Francisco (1)
United States (2) · Germany (1) · South Korea (1) · Thailand (1)
Jae-Gook Shin (1) · Leslie Benet, PhD (1) · Shawn Searle, MD (1) · Steffen Haffner, MD (1) · Tospon Lertwattanachai, B.sc.(Pharm) (1) · Yudong Qiu (1)