4 active not recruiting, 4 completed, 3 recruiting. 3 Not applicable, 3 Phase 1, 2 Early Phase 1, 2 Phase 2, 1 Phase 3.
Follow Pathologic Stage IV Gastric Cancer AJCC v8: new trials by email Literature Review of Pathologic Stage IV Gastric Cancer AJCC v8 trials Research Report on Pathologic Stage IV Gastric Cancer AJCC v8
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Pembrolizumab and Lenvatinib for the Treatment of Advanced, Unresectable, or Metastatic Gastroesophageal Adenocarcinoma Lenvatinib, Pembrolizumab - Advanced Gastric Adenocarcinoma, Advanced Gastroesophageal Junction Adenocarcinoma | Early Phase 1 | Active not recruiting | M.D. Anderson Cancer Center | 15 | 2022-02-14 | 2026-07-16 |
| Ramucirumab and Trifluridine/Tipiracil or Paclitaxel for the Treatment of Patients With Previously Treated Advanced Gastric or Gastroesophageal Junction Cancer Paclitaxel, Quality-of-Life Assessment, Ramucirumab - Clinical Stage III Gastric Cancer AJCC v8, Clinical Stage III Gastroesophageal Junction Adenocarcinoma AJCC v8 | Phase 2 | Recruiting | Academic and Community Cancer Research United | 116 | 2021-06-16 | 2024-04-01 |
| Enhanced Outpatient Symptom Management to Reduce Acute Care Visits Due to Chemotherapy-Related Adverse Events Best Practice, Patient Monitoring, Questionnaire Administration - Clinical Stage IV Esophageal Adenocarcinoma AJCC v8, Clinical Stage IV Esophageal Squamous Cell Carcinoma AJCC v8 | Not applicable | Active not recruiting | M.D. Anderson Cancer Center | 750 | 2021-05-12 | 2026-06-16 |
| PIPAC for the Treatment of Peritoneal Carcinomatosis in Patients With Ovarian, Uterine, Appendiceal, Colorectal, or Gastric Cancer Biopsy, Cisplatin, Doxorubicin - Clinical Stage IV Gastric Cancer AJCC v8, Clinical Stage IVA Gastric Cancer AJCC v8 | Phase 1 | Recruiting | City of Hope Medical Center | 49 | 2020-08-21 | 2026-08-26 |
| Remote Telemonitoring of Patient-Generated Physiologic Health Data and Patient-Reported Outcomes Patient Monitoring, Questionnaire Administration - Clinical Stage 0 Esophageal Adenocarcinoma AJCC v8, Clinical Stage 0 Esophageal Squamous Cell Carcinoma AJCC v8 | Completed | City of Hope Medical Center | 22 | 2020-08-11 | 2026-10-14 | |
| Radiation Therapy for the Treatment of Metastatic Gastrointestinal Cancers Radiation Therapy (RT) - Stage IV Esophageal Adenocarcinoma, Stage IV Esophageal Squamous Cell Carcinoma | Not applicable | Recruiting | University of California, San Francisco | 28 | 2020-08-07 | 2026-08-14 |
| Testing the Addition of Radiotherapy to the Usual Treatment (Chemotherapy) for Patients With Esophageal and Gastric Cancer That Has Spread to a Limited Number of Other Places in the Body Capecitabine, Fluorouracil, Leucovorin - Clinical Stage IV Esophageal Adenocarcinoma AJCC v8, Clinical Stage IV Gastric Cancer AJCC v8 | Phase 3 | Active not recruiting | ECOG-ACRIN Cancer Research Group | 314 | 2020-05-26 | 2026-10-19 |
| Real-Time Monitoring of Chemotherapy Side-Effects in Patients With Gastrointestinal Cancers, RT-CAMSS Study Patient Monitoring System, Questionnaire Administration, Consultation - Clinical Stage 0 Esophageal Adenocarcinoma AJCC v8, Clinical Stage 0 Esophageal Squamous Cell Carcinoma AJCC v8 | Not applicable | Completed | Thomas Jefferson University | 34 | 2020-04-15 | 2025-05-15 |
| Paclitaxel for the Treatment of Gastric or Gastroesophageal Cancer Paclitaxel - Clinical Stage IV Gastric Cancer AJCC v8, Clinical Stage IV Gastroesophageal Junction Adenocarcinoma AJCC v8 | Phase 1 | Active not recruiting | M.D. Anderson Cancer Center | 27 | 2019-12-06 | 2026-10-06 |
| IRX-2, Cyclophosphamide, and Pembrolizumab in Treating Participants With Recurrent or Metastatic Gastric or Gastroesophageal Junction Cancer Cyclophosphamide, Cytokine-based Biologic Agent IRX-2, Pembrolizumab - Clinical Stage IV Gastric Cancer AJCC v8, Clinical Stage IV Gastroesophageal Junction Adenocarcinoma AJCC v8 | Phase 1 / Phase 2 | Completed | City of Hope Medical Center | 9 | 2019-04-30 | 2026-10-21 |
| Pembrolizumab in Treating Patients With Metastatic or Unresectable Gastroesophageal Adenocarcinoma Pembrolizumab - Advanced Gastroesophageal Junction Adenocarcinoma, Clinical Stage III Esophageal Adenocarcinoma AJCC v8 | Early Phase 1 | Completed | M.D. Anderson Cancer Center | 9 | 2018-02-09 | 2023-11-18 |
Colorectal Neoplasms (4) · Gastrointestinal Neoplasms (3) · Stomach Neoplasms (3) · Adenocarcinoma Of Esophagus (2) · Carcinoma, Hepatocellular (2) · Esophageal Neoplasms (2) · Ovarian Neoplasms (2) · Pancreatic Neoplasms (2) · Peritoneal Neoplasms (2) · Anal Canal Carcinoma (1) · Anus Neoplasms (1) · Appendiceal Neoplasms (1) · Carcinoma, Renal Cell (1) · Colonic Neoplasms (1) · Esophageal Squamous Cell Carcinoma (1)
Digestive System Diseases (6) · Digestive System Neoplasms (6) · Neoplasms by Site (6) · Colonic Diseases (5) · Gastrointestinal Diseases (5) · Intestinal Diseases (5) · Intestinal Neoplasms (5) · Neoplasms (5) · Rectal Diseases (5) · Endocrine Gland Neoplasms (4) · Endocrine System Diseases (4) · Adenocarcinoma (3) · Carcinoma (3) · Neoplasms by Histologic Type (3) · Neoplasms, Glandular and Epithelial (3)
pembrolizumab (3) · Fluorouracil (2) · Leucovorin (2) · Oxaliplatin (2) · Paclitaxel (2) · Radiation (2) · Radiotherapy (2) · Remote Patient Monitoring (2) · Taxes (2) · dehydroftorafur (2) · 1,2-diaminocyclohexaneplatinum II citrate (1) · Biopsy (1) · Capecitabine (1) · Cisplatin (1) · Cyclophosphamide (1)
M.D. Anderson Cancer Center (4) · City of Hope Medical Center (3) · Academic and Community Cancer Research United (1) · ECOG-ACRIN Cancer Research Group (1) · Thomas Jefferson University (1) · University of California, San Francisco (1)
United States (11)
Brian D Badgwell (1) · Jaffer A Ajani (1) · Joseph Chao (1) · Kuang-Yi Wen, MD (1) · Laleh Melstrom (1) · Mariela Blum (1) · Mary Feng, MD (1) · Mohamad B Sonbol (1) · Mustafa Raoof, MD (1) · Nataliya V Uboha (1) · Ryan W Huey, MD (1) · Thanh H Dellinger, MD (1)
P30CA033572 (2), P30CA015083 (1), U10CA180820 (1)