6 completed, 5 unknown, 1 terminated. 12 Phase 3, 5 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 12 | Completed 6, Unknown 5, Terminated 1 |
| Phase 2 | 5 | Unknown 4, Completed 1 |
Follow Painful Diabetic Neuropathy: new trials by email Literature Review of Painful Diabetic Neuropathy trials Research Report on Painful Diabetic Neuropathy
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Study to Evaluate Pregabalin in Painful Diabetic Peripheral Neuropathy pregabalin sustained-release tablets, Placebo - Painful Diabetic Neuropathy | Phase 3 | Unknown | CSPC Ouyi Pharmaceutical Co., Ltd. | 358 | 2024-05-15 | 2024-04-30 |
| The Benefits of Vitamin D 5000 IU as Add on Therapy in the Management of Painful Diabetic Neuropathy Patient Standard therapy, Vitamin D 5,000IU Oral Tablet - Painful Diabetic Neuropathy | Phase 2 / Phase 3 | Unknown | Duta Wacana Christian University | 60 | 2020-11-03 | 2020-12-30 |
| The Benefits of Astaxanthin as Add on Therapy in the Management of Painful Diabetic Neuropathy Patient Standard therapy, Astaxanthin - Painful Diabetic Neuropathy | Phase 2 / Phase 3 | Unknown | Duta Wacana Christian University | 60 | 2020-11-03 | 2020-12-30 |
| The Benefits of Vitamin B Combination as Add on Therapy in the Management of Painful Diabetic Neuropathy Patient Standard therapy, Vitamin B combination - Painful Diabetic Neuropathy | Phase 2 / Phase 3 | Unknown | Duta Wacana Christian University | 60 | 2020-11-03 | 2020-12-30 |
| Extension of Phase 3 Gene Therapy for Painful Diabetic Neuropathy Long-Term Follow-Up of Patients who Received Engensis (VM202), Long-Term Follow-Up of Patients who Received Placebo - Painful Diabetic Neuropathy, Diabetic Neuropathy, Painful | Phase 3 | Completed | Helixmith Co., Ltd. | 101 | 2019-02-04 | 2025-10-09 |
| Phase 3 Gene Therapy for Painful Diabetic Neuropathy Engensis (VM202), placebo - Painful Diabetic Neuropathy, Diabetic Neuropathy, Painful | Phase 3 | Completed | Helixmith Co., Ltd. | 507 | 2016-04-01 | 2025-10-09 |
| Eslicarbazepine Acetate as Therapy in Diabetic Neuropathic Pain Eslicarbazepine acetate (BIA 2-093), Placebo - Painful Diabetic Neuropathy | Phase 3 | Terminated | Bial - Portela C S.A. | 332 | 2010-11-01 | 2014-07-18 |
| Capsaicin Nanoparticle in Patient With Painful Diabetic Neuropathy 0.75% capsaicin nanoparticle cream, Placebo - Painful Diabetic Neuropathy | Phase 2 / Phase 3 | Unknown | Mahidol University | 60 | 2009-09-01 | 2013-04-11 |
| A Trial to Assess the Efficacy and Safety of 400mg/Day Lacosamide in Subjects With Painful Diabetic Neuropathy SPM 929, Placebo - Painful Diabetic Neuropathy | Phase 3 | Completed | UCB Pharma | 551 | 2006-06-30 | 2024-03-22 |
| A Trial to Assess the Long-term Safety and Efficacy of Lacosamide in Subjects With Painful Diabetic Neuropathy Lacosamide - Painful Diabetic Neuropathy | Phase 3 | Completed | UCB Pharma | 371 | 2004-12-21 | 2023-07-24 |
| Study Evaluating Long-term Safety and Efficacy of Lacosamide in Subjects With Painful Distal Diabetic Neuropathy. Lacosamide - Painful Diabetic Neuropathy | Phase 3 | Completed | UCB Pharma | 621 | 2004-05-01 | 2023-09-21 |
| Electromagnetic Stimulation (FREMS) in Patients With Painful Diabetic Neuropathy Frequency-modulated electromagnetic neural stimulation - Painful Diabetic Neuropathy | Phase 2 / Phase 3 | Completed | IRCCS San Raffaele | 38 | 2002-03-01 | 2006-06-15 |
Diabetic Neuropathies (12) · Pain (2) · Neuralgia (1) · Peripheral Nervous System Diseases (1)
Diabetes Complications (12) · Diabetes Mellitus (12) · Endocrine System Diseases (12) · Nervous System Diseases (12) · Neuromuscular Diseases (12) · Peripheral Nervous System Diseases (11) · Neurologic Manifestations (3) · Pathological Conditions, Signs and Symptoms (3) · Signs and Symptoms (3) · Pain (1)
Lacosamide (3) · Standard of Care (3) · 2-(acetylamino)-3-methoxy-N-(phenylmethyl)-, (2R)- (1) · Tablets (1) · Vitamin B Complex (1) · Vitamin D (1) · astaxanthine (1) · cyanocobalamin, pyridoxine, thiamine drug combination (1) · eslicarbazepine acetate (1)
Duta Wacana Christian University (3) · UCB Pharma (3) · Helixmith Co., Ltd. (2) · Bial - Portela C S.A. (1) · CSPC Ouyi Pharmaceutical Co., Ltd. (1) · IRCCS San Raffaele (1) · Mahidol University (1)
Germany (3) · Indonesia (3) · Italy (2) · United States (2) · Austria (1) · Belgium (1) · Bulgaria (1) · Czechia (1) · Finland (1) · France (1) · Hungary (1) · Poland (1) · Portugal (1) · Romania (1) · Russia (1)
Rizaldy T Pinzon, MD, MSc, PhD (2) · Chuthamanee Suthisisang, PhD. (1) · Emanuele Bosi, MD (1) · John A Kessler, MD (1) · John A. Kessler, MD (1) · Rizaldy Pinzon, MD, MSc, PhD (1)
PMID 15834546, PMID 18403219, PMID 29588972, PMID 33465273, PMID 34984028
2004 (2), 2005 (1)