4 recruiting, 1 active not recruiting, 1 not yet recruiting, 1 suspended. 2 Not applicable, 2 Phase 2, 1 Early Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 2 | Active not recruiting 1, Not yet recruiting 1 |
| Phase 2 | 2 | Recruiting 2 |
| Early Phase 1 | 1 | Suspended 1 |
Follow Ototoxicity, Drug-Induced: new trials by email Literature Review of Ototoxicity, Drug-Induced trials Research Report on Ototoxicity, Drug-Induced
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Cisplatin-induced Cochlear and Vestibular Damage in Head and Neck Cancer Ototoxic Hearing Loss, Ototoxicity, Drug-Induced | Recruiting | Simon Jäger | 55 | 2026-01-20 | 2026-10-20 | |
| Prevention of Ototoxicity in NTM Patients Treated With IV Amikacin ORC-13661, Placebo - Ototoxicity, Drug-Induced | Phase 2 | Recruiting | Kevin Winthrop | 105 | 2025-06-02 | 2026-10-01 |
| Analysis of Risk Factors for Hearing Loss in Survivors of Cancer Occurred During Childhood, Adolescence or Young Adulthood Audiogram - Ototoxicity, Drug-Induced, Ototoxicity, Radiation-Induced | Not applicable | Not yet recruiting | Gustave Roussy, Cancer Campus, Grand Paris | 500 | 2025-05-01 | 2025-05-04 |
| Protective Effect of Acetylcysteine Against Cisplatinum-Induced Ototoxicity: A Randomized Controlled Trial Acetyl cysteine, Normal Saline - Cisplatin-induced Ototoxicity, Sensorineural Hearing Loss | Phase 2 | Recruiting | Siriraj Hospital | 40 | 2024-12-23 | 2026-01-23 |
| Diagnostic of Various Ototoxicity Induced by Cancer Treatment Auditory, vestibular and electrophysiological investigations, Biologic investigations; seric proteins - Ototoxicity, Drug-Induced | Recruiting | Direction Centrale du Service de Santé des Armées | 540 | 2024-06-19 | 2024-07-08 | |
| Comparative Study of the Quality of Life of Patients Suffering From OTOTOXICITY Due to Chemotherapy Based on Platinum Salts Fitted With a Hearing Aid Compared to Those Not Fitted. Patients suffering from chemotherapy-induced ototoxicity, Patients suffring from chemotherapy-induced ototoxicity wearing hearing aids - Cancer, Ototoxicity, Drug-Induced | Not applicable | Active not recruiting | Institut de Cancérologie de Lorraine | 52 | 2024-01-04 | 2026-10-22 |
| Sodium Thiosulfate Otoprotection During Salvage Cisplatin Therapy Sodium Thiosulfate - Ototoxicity, Drug-Induced | Early Phase 1 | Suspended | Children's Hospital Medical Center, Cincinnati | 33 | 2023-03-01 | 2026-10-22 |
Ototoxicity (7) · Hearing Loss (2) · Hearing Loss, Sensorineural (2) · Neoplasms (2) · Deafness (1) · Dizziness (1) · Head and Neck Neoplasms (1) · Hearing Disorders (1) · Hepatoblastoma (1) · Neoplasms, Germ Cell and Embryonal (1) · Squamous Cell Carcinoma of Head and Neck (1) · Vestibular Diseases (1)
Chemically-Induced Disorders (7) · Drug-Related Side Effects and Adverse Reactions (7) · Ear Diseases (7) · Otorhinolaryngologic Diseases (7) · Pathologic Processes (7) · Pathological Conditions, Signs and Symptoms (7) · Radiation Injuries (7) · Wounds and Injuries (7) · Nervous System Diseases (4) · Neurologic Manifestations (4) · Sensation Disorders (4) · Signs and Symptoms (4) · Hearing Disorders (3) · Neoplasms (2) · Neoplasms by Histologic Type (2)
Acetylcysteine (1) · Audiometry (1) · Cisplatin (1) · ORC-13661 (1) · Saline Solution (1) · Vorinostat (1) · sodium thiosulfate (1)
Children's Hospital Medical Center, Cincinnati (1) · Direction Centrale du Service de Santé des Armées (1) · Gustave Roussy, Cancer Campus, Grand Paris (1) · Institut de Cancérologie de Lorraine (1) · Kevin Winthrop (1) · Simon Jäger (1) · Siriraj Hospital (1)
France (3) · United States (2) · Germany (1) · Thailand (1)
Brice Fresneau, MD, PhD (1) · Edwin Rubel, PhD (1) · Kanthong Thongyai, Master (1) · Katherine Somers, MD (1) · Kevin L Winthrop, MD, MPH (1)
U01DC020175 (1)