7 unknown, 6 recruiting, 2 not yet recruiting, 1 completed. 3 Not applicable, 2 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 3 | Not yet recruiting 1, Recruiting 1, Unknown 1 |
| Phase 2 | 2 | Recruiting 1, Withdrawn 1 |
Follow Organoids: new trials by email Literature Review of Organoids trials Research Report on Organoids
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Analysis of Early Neurodevelopmental Alterations in Bipolar Disorder Based on Cortical Organoid Models blood sample - Bipolar Disorder (BD), Organoids | Not applicable | Not yet recruiting | Assistance Publique Hopitaux De Marseille | 10 | 2025-06-01 | 2025-05-13 |
| Testing a Functional Precision Medicine Approach to Select Chemotherapy for Metastatic Colorectal Cancer (COSENSE-1) FOLFOX or FOLFIRI - Tumor, Colorectal, Organoids | Phase 2 | Recruiting | St. Olavs Hospital | 148 | 2025-05-23 | 2026-07-20 |
| Drug Sensitivity of Hydrothorax and Ascite Organoids from Breast Cancer organoid drug test - Breast Cancer Metastatic, Hydrothorax | Recruiting | Second Affiliated Hospital, Zhejiang University, School of Medicine | 90 | 2024-11-09 | 2025-01-07 | |
| Organoid Models of Hepatocellular Carcinoma organoids models - Hepatocellular Carcinoma, Organoids | Not applicable | Recruiting | Fondazione Policlinico Universitario Agostino Gemelli IRCCS | 150 | 2024-10-01 | 2026-09-21 |
| Organoids Based Drug Sensitivity in Neoadjuvant Chemotherapy of Breast Cancer Biopsy - Organoids, Breast Cancer | Recruiting | Second Affiliated Hospital, Zhejiang University, School of Medicine | 58 | 2023-12-06 | 2025-01-07 | |
| A Clinical Study Aims to Assess the Consistency of Clinical Efficacy in Colorectal Cancer Treatment and Drug Susceptibility Outcomes Using a Novel Drug Susceptibility Testing Method Colorectal Cancer, Organoids | Unknown | Funan Liu | 105 | 2023-10-18 | 2024-02-07 | |
| A Clinical Study Aims to Assess the Consistency of Clinical Efficacy in Gastric Cancer Treatment and Drug Susceptibility Outcomes Using a Novel Drug Susceptibility Testing Method Gastric Cancer, Organoids | Unknown | Funan Liu | 104 | 2023-10-18 | 2024-02-07 | |
| Breast Cancer Subtype Characterization Through Patient's Derived Organoids. Breast Cancer, Organoids | Recruiting | Fondazione Policlinico Universitario Agostino Gemelli IRCCS | 306 | 2023-06-15 | 2024-03-18 | |
| Clinical Transformation of Organoid Model to Predict the Efficacy of GC in the Treatment of Intrahepatic Cholangiocarcinoma gemcitabine + cisplatin - Organoids, Intrahepatic Cholangiocarcinoma | Not yet recruiting | Chengjun Sui,MD | 40 | 2023-01-01 | 2022-12-09 | |
| Patient-derived-organoid (PDO) Guided Versus Conventional Therapy for Advanced Inoperable Abdominal Tumors PDO-guided treatment, standard of care - Organoids | Phase 2 | Withdrawn | Chinese University of Hong Kong | 2022-07-04 | 2023-03-29 | |
| Bern Human Organoid-Study to Study Host-microbe Interaction Organoids, Allergy and Immunology | Recruiting | Insel Gruppe AG, University Hospital Bern | 100 | 2022-03-31 | 2024-12-11 | |
| Organoids-on-a-chip for Colorectal Cancer and in Vitro Screening of Chemotherapeutic Drugs comprehensive treatment after MDT discussion - Colorectal Neoplasms, Organoids | Unknown | Peking University People's Hospital | 52 | 2021-05-31 | 2021-08-18 | |
| Cetuximab Sensitivity Correlation Between Patient-Derived Organoids and Clinical Response in Colon Cancer Patients. Tumor biopsy - Colon Cancer, Organoids | Unknown | D1 Medical Technology (Shanghai) Co., Ltd, China | 80 | 2021-04-15 | 2021-08-13 | |
| Translational Analysis In Longitudinal Series of Ovarian Cancer ORganoids Tumor biopsy - Organoids, Epithelial Ovarian Cancer | Unknown | Fondazione Policlinico Universitario Agostino Gemelli IRCCS | 48 | 2020-05-12 | 2020-09-18 | |
| Selecting Chemotherapy With High-throughput Drug Screen Assay Using Patient Derived Organoids in Patients With Refractory Solid Tumours (SCORE) Tumor Core Biopsy, Blood sampling - Organoids, HNSCC | Not applicable | Unknown | National University Hospital, Singapore | 35 | 2019-05-29 | 2020-09-09 |
| Organoids in Predicting Chemoradiation Sensitivity on Rectal Cancer Biopsy - Organoids, Rectal Cancer | Unknown | Zhen Zhang | 80 | 2018-08-17 | 2018-08-20 | |
| The Innervation of Human Gut Sensory Epithelial Cells Organoids | Completed | Duke University | 42 | 2017-09-05 | 2023-01-06 |
Colorectal Neoplasms (4) · Breast Neoplasms (2) · Carcinoma, Ovarian Epithelial (2) · Ascites (1) · Bipolar Disorder (1) · Carcinoma, Hepatocellular (1) · Cholangiocarcinoma (1) · Colonic Neoplasms (1) · Digestive System Diseases (1) · Hydrothorax (1) · Hypersensitivity (1) · Neoplasm Metastasis (1) · Rectal Neoplasms (1) · Squamous Cell Carcinoma of Head and Neck (1) · Stomach Neoplasms (1)
Neoplasms (12) · Neoplasms by Site (11) · Digestive System Neoplasms (8) · Digestive System Diseases (7) · Gastrointestinal Diseases (7) · Gastrointestinal Neoplasms (7) · Intestinal Diseases (6) · Intestinal Neoplasms (6) · Colonic Diseases (5) · Rectal Diseases (5) · Carcinoma (4) · Neoplasms by Histologic Type (4) · Neoplasms, Glandular and Epithelial (4) · Adenocarcinoma (2) · Adnexal Diseases (2)
Blood Specimen Collection (3) · Biopsy (2) · Folfox protocol (1) · Standard of Care (1)
Fondazione Policlinico Universitario Agostino Gemelli IRCCS (3) · Funan Liu (2) · Second Affiliated Hospital, Zhejiang University, School of Medicine (2) · Assistance Publique Hopitaux De Marseille (1) · Chengjun Sui,MD (1) · Chinese University of Hong Kong (1) · D1 Medical Technology (Shanghai) Co., Ltd, China (1) · Duke University (1) · Insel Gruppe AG, University Hospital Bern (1) · National University Hospital, Singapore (1) · Peking University People's Hospital (1) · St. Olavs Hospital (1) · Zhen Zhang (1)
China (7) · Italy (3) · Hong Kong (1) · Norway (1) · Singapore (1) · Switzerland (1) · United States (1)
Funan Liu, doctor (2) · Zhenning Wang, doctor (2) · Anna Fagotti, Professor (1) · Camilla Nero, PhD (1) · Carmine Conte, MD (1) · Carolina Bottoni, MD (1) · Claudio Sette, Professor (1) · Eleonari Cesari, PhD (1) · Francesca Romana Ponziani, PI (1) · Giovanni Scambia, Professor (1) · Giuseppe Vizzielli, PhD (1) · Guoqiang Hua, PhD (1) · Jian Huang (1) · Junjie Peng, Dr. (1)
PMID 24849521, PMID 25304260, PMID 25877891, PMID 26782955, PMID 26998845, PMID 30213835, PMID 31171691