2 terminated. 2 Phase 2, 2 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 2 | Terminated 2 |
| Phase 3 | 2 | Terminated 2 |
Follow Nerve Degeneration: new trials by email Literature Review of Nerve Degeneration trials Research Report on Nerve Degeneration
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Study to Evaluate Efficacy and Safety of Vatiquinone for Treating Mitochondrial Disease in Participants With Refractory Epilepsy Vatiquinone, Placebo - Mitochondrial Diseases, Drug Resistant Epilepsy | Phase 2 / Phase 3 | Terminated | PTC Therapeutics | 68 | 2020-09-28 | 2026-03-31 |
| Study to Investigate the Safety and Efficacy of Lithium in Volunteers With Amyotrophic Lateral Sclerosis (ALS) Lithium Carbonate, Riluzole, placebo - Amyotrophic Lateral Sclerosis | Phase 2 / Phase 3 | Terminated | Massachusetts General Hospital | 84 | 2009-01-01 | 2011-04-19 |
Amyotrophic Lateral Sclerosis (1) · Diffuse Cerebral Sclerosis of Schilder (1) · Drug Resistant Epilepsy (1) · Leigh Disease (1) · MELAS Syndrome (1) · MERRF Syndrome (1) · Mitochondrial Diseases (1) · Mitochondrial encephalopathy (1) · Pontocerebellar Hypoplasia Type 6 (1) · Seizures (1) · Status Epilepticus (1)
Central Nervous System Diseases (2) · Metabolic Diseases (2) · Nervous System Diseases (2) · Neuromuscular Diseases (2) · Nutritional and Metabolic Diseases (2) · Pathologic Processes (2) · Pathological Conditions, Signs and Symptoms (2) · Autoimmune Diseases (1) · Autoimmune Diseases of the Nervous System (1) · Brain Diseases (1) · Brain Diseases, Metabolic (1) · Brain Diseases, Metabolic, Inborn (1) · Carbohydrate Metabolism, Inborn Errors (1) · Cardiovascular Diseases (1) · Cerebral Small Vessel Diseases (1)
Lithium Carbonate (1) · Riluzole (1) · alpha-tocotrienol quinone (1)
Massachusetts General Hospital (1) · PTC Therapeutics (1)
Canada (2) · United States (2) · France (1) · Italy (1) · Japan (1) · Poland (1) · Spain (1) · Sweden (1) · United Kingdom (1)
Jinsy Andrews, MD (1) · Lorne Zinman, MD, MSc, FRCPC (1) · Merit Cudkowicz, MD, MSc (1) · Swati Aggarwal, MD (1) · Vinay Penematsa, MD (1)
U01NS049640 (1)