458 completed, 231 recruiting, 156 unknown, 67 not yet recruiting. 1106 Not applicable.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 1106 | Completed 458, Recruiting 231, Unknown 156, Not yet recruiting 67, Active not recruiting 65, Terminated 65, Withdrawn 47, Suspended 11, Enrolling by invitation 6 |
Follow Neoplasms, Nerve Tissue: new trials by email Literature Review of Neoplasms, Nerve Tissue trials Research Report on Neoplasms, Nerve Tissue
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Study Using Brain Stimulation and Behavioral Therapy to Increase Extent of Resection in Low-Grade Gliomas RNS System Implantation - Glioma, Glioma Intracranial | Not applicable | Not yet recruiting | Medical College of Wisconsin | 3 | 2028-08-01 | 2026-10-13 |
| STAGE-MTC Trial Thyroid Lobectomy With Ipsilateral Central Neck Dissection Biospecimen Collection, FDG-Positron Emission Tomography and Computed Tomography Scan, Ga-68 PET/CT Scan - Thyroid Gland Medullary Carcinoma | Not applicable | Not yet recruiting | Jonsson Comprehensive Cancer Center | 100 | 2027-09-02 | 2026-10-19 |
| Residual IDH1-Mutant Tumor Cell Quantification Study UR-ddPCR - Glioma | Not applicable | Not yet recruiting | NYU Langone Health | 105 | 2027-08-01 | 2026-09-29 |
| Assessing the Efficacy of Repeat, Monthly Treatments of Alexandrite Laser for NF1-associated Cutaneous Neurofibromas (cNFs) GentleMax Pro (with skin cooling), GentleMax Pro (without skin cooling) - Neurofibromatosis 1 (NF1), Neurofibromatosis Type I | Not applicable | Suspended | Massachusetts General Hospital | 10 | 2027-01-01 | 2026-06-04 |
| A Comparative Study Evaluating the Impact of Intensive Dietary Care on Weight Change and Biological Parameters in Patients Who Underwent Surgery for Craniopharyngioma During the First Postoperative Year Intensive dietary care - Craniopharyngioma | Not applicable | Not yet recruiting | Assistance Publique Hopitaux De Marseille | 75 | 2027-01-01 | 2026-09-22 |
| Role of ChatGPT in Vestibular Schwannoma Management Use of chatGPT for 1 week - Vestibular Schwannoma | Not applicable | Withdrawn | University of Southern California | 2027-01-01 | 2026-01-13 | |
| ctDNA-Guided Intraventricular Therapy for CNS Malignancies CSF ctDNA-Guided Clinical Management - Leptomeningeal Disease, Glioblastoma | Not applicable | Not yet recruiting | Alireza Mansouri | 77 | 2027-01-01 | 2026-07-08 |
| A Multicenter Randomized Open-Label Trial Evaluating ctDNA-Guided Interruption Versus Standard of Care Immune-Checkpoint Inhibitor (ICI) Therapy In Patients With Advanced / Metastatic Solid Tumors. Signatera Genome ultra-sensitive ctDNA blood test - NSCLC (Advanced Non-small Cell Lung Cancer), NSCLC (Non-small Cell Lung Cancer) | Not applicable | Not yet recruiting | Natera, Inc. | 920 | 2027-01-01 | 2026-10-27 |
| Trial Comparing CPDMA Versus Standard Breadloafing in WLE Specimens of Stage 1-II Cutaneous Melanoma Wide Local Excision - Cutaneous Melanoma, Stage II, Cutaneous Melanoma | Not applicable | Not yet recruiting | University of Nebraska | 282 | 2026-12-24 | 2026-10-09 |
| Personalized Cancer Support (Thrive Track) to Manage the Emotional Needs of Young Adults With Thyroid, Melanoma and Testicular Cancer, PerCS-YA Trial Internet-Based Intervention, Interview, Questionnaire Administration - Differentiated Thyroid Gland Carcinoma, Malignant Testicular Neoplasm | Not applicable | Not yet recruiting | University of Michigan Rogel Cancer Center | 142 | 2026-12-01 | 2026-10-15 |
| Exercise and Nutritional Intervention in Patients With Melanoma Receiving Immunotherapy Structured Resistance Exercise, Individualized Nutritional Support - Melanoma | Not applicable | Not yet recruiting | Institute of Oncology Ljubljana | 40 | 2026-12-01 | 2026-10-07 |
| Safety and Efficacy of Autologous Natural Killer Cell Therapy (CHANK-101) in Patients With Recurrent Glioblastoma CHANK-101 - Recurrent Glioblastoma | Not applicable | Not yet recruiting | Dong-A University Hospital | 60 | 2026-11-29 | 2026-11-02 |
| my.naviGATE: A Guide to After-Treatment Effects for Adolescents and Young Adults my.naviGATE Digital Tool - Sarcoma, Osteosarcoma | Not applicable | Not yet recruiting | Dana-Farber Cancer Institute | 143 | 2026-11-20 | 2026-10-29 |
| Telemedicine-mHealth Symptom Cluster Intervention for Advanced Cancer Patients: Finding Our Center Under Stress (FOCUS) mHealth Intervention - Lung Cancer, Breast Cancer | Not applicable | Suspended | Ohio State University Comprehensive Cancer Center | 120 | 2026-11-15 | 2026-08-17 |
| GLAD-KE GLioma Biomarker and Safety Assessment During Dietary Ketone Elevation Subtitle: A Surgical Biomarker Discovery Study of Ketogenic Therapy in Recurrent Glioma Arm 1 will use Ketone supplement 80 gm daily, Arm 2 will follow Ketogenic Diet 7 days leading up to the clinically indicated surgery. - Recurrent Glioma (Glioblastoma Multiforme) | Not applicable | Not yet recruiting | Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | 20 | 2026-11-05 | 2026-10-28 |
| Feasibility of an Enhanced Symptom Monitoring and Expedited Subspecialty Care Referral Intervention to Improve Side Effect Management for Patients With Melanoma Receiving an Immune Checkpoint Inhibitor Electronic Health Record Review, Internet-Based Intervention, Patient Navigation - Melanoma | Not applicable | Not yet recruiting | OHSU Knight Cancer Institute | 50 | 2026-11-01 | 2026-06-22 |
| Feasibility Assessment of a Medical Device for Tumour Cell Retention and Radiotherapy Sensitization in Patients With Suspected High-grade Glioma GlioHook device - Glioma, High-Grade Glioma (HGG) | Not applicable | Not yet recruiting | Batea Oncology | 15 | 2026-10-30 | 2026-07-27 |
| Tear Fluid for the Detection of Tumor-associated Extracellular Vesicles in Glioblastoma Patients Biospecimen Collection, Electronic Health Record Review, Questionnaire Administration - Glioblastoma | Not applicable | Recruiting | City of Hope Medical Center | 30 | 2026-10-23 | 2026-10-30 |
| Detection of the BRAF V600E Mutation in Liquid Biopsy Using the CRISPR/Cas12a System Novel CRISPR/Cas12a Electrochemical Bioassay, Reference Standard Molecular Diagnostics (NGS and ddPCR), Serial Peripheral Blood Sampling for Liquid Biopsy - Unresectable Metastatic Melanoma | Not applicable | Recruiting | Masaryk Memorial Cancer Institute | 17 | 2026-10-20 | 2026-10-16 |
| Aggressive Lipid Lowering Therapy in ICI-Treated Melanoma Statins (atorvastatin, rosuvastatin, simvastatin, or pravastatin), +/- ezetimibe, +/- PCSK9 inhibitor (alirocumab, evolocumab, inclisiran) - Melanoma | Not applicable | Recruiting | University of Colorado, Denver | 40 | 2026-10-19 | 2026-11-02 |
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Melanoma (342) · Glioblastoma (241) · Glioma (236) · Brain Neoplasms (131) · Neoplasms (67) · Breast Neoplasms (64) · Neuroblastoma (56) · Meningioma (52) · Neuroendocrine Tumors (50) · Astrocytoma (43) · Sarcoma (42) · Skin Neoplasms (40) · Neuroma, Acoustic (38) · Neurofibromatosis 1 (33) · Lung Neoplasms (30)
Neoplasms by Histologic Type (1104) · Neoplasms (1039) · Neuroectodermal Tumors (1017) · Neoplasms, Germ Cell and Embryonal (1014) · Neoplasms by Site (634) · Neoplasms, Glandular and Epithelial (613) · Neoplasms, Neuroepithelial (522) · Neuroendocrine Tumors (451) · Skin and Connective Tissue Diseases (371) · Skin Diseases (367) · Nevi and Melanomas (363) · Skin Neoplasms (306) · Nervous System Diseases (293) · Nervous System Neoplasms (224)
Magnetic Resonance Spectroscopy (34) · Blood Specimen Collection (31) · Radiotherapy (17) · Radiosurgery (15) · Bevacizumab (13) · Magnetic Resonance Imaging (12) · Radiation (11) · Surgical Procedures, Operative (11) · Temozolomide (11) · Carboplatin (10) · Biopsy (9) · Etoposide (9) · Melphalan (9) · Standard of Care (9) · Surveys and Questionnaires (9)
Massachusetts General Hospital (27) · M.D. Anderson Cancer Center (23) · Memorial Sloan Kettering Cancer Center (19) · Northwestern University (15) · Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins (14) · Institut Curie (13) · Hospices Civils de Lyon (12) · Institute of Oncology Ljubljana (11) · Mayo Clinic (11) · National Cancer Institute (NCI) (11) · Beijing Tiantan Hospital (10) · Case Comprehensive Cancer Center (10) · Centre Hospitalier Universitaire de Nice (10) · Jonsson Comprehensive Cancer Center (10) · University Medical Center Groningen (10)
United States (426) · France (145) · China (79) · Italy (50) · Netherlands (46) · Germany (44) · United Kingdom (44) · Canada (41) · Denmark (26) · Switzerland (22) · Sweden (21) · Australia (16) · Belgium (15) · Austria (14) · Norway (13)
June K Robinson, MD (6) · Alexander Dmitriev, MD (5) · Ana-Maria Vranceanu, PhD (4) · Elizabeth Gerstner, MD (4) · Anhua Wu, MD (3) · Donna Morgan Murray, PhD (3) · Giselle Sholler, MD (3) · Graeme Woodworth, MD (3) · John Boockvar, MD (3) · Staci M Peron, Ph.D. (3) · Vanessa Merker, PhD (3) · Wen Cheng, MD (3) · Yu Shi, MD (3) · A. M.E. Walenkamp, MD, PhD (2) · Amod Sarnaik, M.D. (2)
PMID 38968568, PMID 24418949, PMID 35575302, PMID 38908005, PMID 41308679, PMID 42687123, PMID 11587600, PMID 11710496, PMID 11780887, PMID 11981398, PMID 12525530, PMID 12925338, PMID 12959431, PMID 14724495, PMID 15354006, PMID 15758009, PMID 16163448, PMID 16618863, PMID 17147966, PMID 17224540, PMID 17438254, PMID 17764513, PMID 18195220, PMID 18258332, PMID 18283179, PMID 18406492, PMID 18445844, PMID 18543042, PMID 18564433, PMID 18797204, PMID 18839433, PMID 18978740, PMID 19139429, PMID 19167838, PMID 19289774, PMID 19380671, PMID 19388140, PMID 19645932, PMID 19659978, PMID 20083705, PMID 20231676, PMID 20400100, PMID 20513615, PMID 20658641, PMID 20682696, PMID 20802221, PMID 20925951, PMID 21058288, PMID 21062428, PMID 21090893
P30CA014089 (4), P30CA006973 (3), P30CA016672 (3), P30CA072720 (3), P30CA138292 (3), 2009 (2), 2016 (2), 2018 (2), P01CA021239 (2), P30CA013330 (2), P30CA016056 (2), P30CA043703 (2), P30CA124435 (2), R37CA276851 (2), U01CA062475 (2)