15 completed, 5 recruiting, 4 not yet recruiting, 2 enrolling by invitation. 20 Not applicable, 2 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 20 | Completed 13, Recruiting 3, Not yet recruiting 2, Active not recruiting 1, Enrolling by invitation 1 |
| Phase 3 | 2 | Completed 1, Recruiting 1 |
Follow Moral Injury: new trials by email Literature Review of Moral Injury trials Research Report on Moral Injury
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Coping and Adaptation for Recovery From Moral Injury: A Group Intervention for Clinical Psychology Residents CARE-MI Group Intervention - Moral Distress, Moral Injury | Not applicable | Not yet recruiting | Universidad Complutense de Madrid | 10 | 2026-12-10 | 2026-10-21 |
| Mobile-Based Resilience Intervention for Moral Injury, Compassion Fatigue, and Distress in ICU Nurses Behavioral - Moral Injury | Not applicable | Not yet recruiting | Alexandria University | 160 | 2026-10-01 | 2026-10-27 |
| Comparing Two Moral Injury Treatments Acceptance and Commitment Therapy for Moral Injury (ACT-MI), Present Centered Therapy for Moral Injury (PCT-MI) - Moral Injury | Not applicable | Enrolling by invitation | VA Eastern Colorado Health Care System | 180 | 2026-09-28 | 2026-10-06 |
| Moral Injury Study Among Healthcare Professionals in Psychiatric Facilities in the PACA Region Self-Questionnaires for Healthcare Workers - Moral Injury | Not yet recruiting | Centre Hospitalier Intercommunal de Toulon La Seyne sur Mer | 2688 | 2026-07-01 | 2026-07-07 | |
| Professional Contributions and Social Value in High-Acuity Medical Care Settings Experience in high-acuity clinical care settings - Professional Burnout, Moral Injury | Not yet recruiting | Kaohsiung Medical University Chung-Ho Memorial Hospital | 1350 | 2026-06-25 | 2026-07-07 | |
| Integrative Bilateral Cervical Sympathetic Blocks for Trauma-Related Symptoms in Special Operations Veterans: A Prospective Case Series stellate ganglion block with 0.5% ropivacaine - PTSD, Trauma-related Mental Health Symptoms | Recruiting | Reset Medical and Wellness Center | 75 | 2026-03-20 | 2026-03-20 | |
| A Study of Moral Distress, Moral Injury and Post-Traumatic Stress for Nurses Surveys - Moral Injury, Moral Distress | Enrolling by invitation | Mayo Clinic | 21300 | 2026-03-03 | 2026-09-17 | |
| Moral Injury in French Healthcare Workers Self-Questionnaires for Healthcare Workers - Moral Injury | Not applicable | Recruiting | Centre Hospitalier Intercommunal de Toulon La Seyne sur Mer | 3073 | 2025-11-19 | 2026-07-07 |
| Role Model-Based Ethics Education and Moral Injury Prevention in Second-Year Medical Students Role Model-Based Ethics Education (Standard Intensity), Role Model-Based Ethics Education (Enhanced Intensity) - Moral Injury, Perceived Stress | Not applicable | Completed | Chun Lun Hsu | 101 | 2025-11-01 | 2026-06-18 |
| Mental Health Clinician / Chaplain Collaboration facilitate forgiveness and community connection to address symptoms of moral injury - Moral Injury | Not applicable | Recruiting | Central Arkansas Veterans Healthcare System | 20 | 2025-04-14 | 2026-05-11 |
| A Comprehensive Group Intervention for Psychosocial Personnel at Risk of Stress and Moral Injury CARE MI, TAU: Treatment as usual - Moral Injury, TEPT | Not applicable | Completed | Universidad Complutense de Madrid | 92 | 2025-02-10 | 2026-10-20 |
| Examining 3,4-methylenedioxymethamphetamine (MDMA) Effects on Psychological, Relational and Hyperarousal-Related Neural Reactivity Mechanisms in Veterans With PTSD and Moral Injury MDMA-AT, SEA-IT - PTSD, Post Traumatic Stress Disorder, Moral Injury | Phase 3 | Recruiting | Herzog Hospital | 60 | 2024-02-18 | 2024-05-01 |
| Better Together Physician Coaching to Mitigate Burnout in Male-Identifying Trainees Better Together Physician Coaching Program, No intervention - placebo control - Burnout, Professional, Self Compassion | Not applicable | Completed | University of Colorado, Denver | 41 | 2023-01-02 | 2023-09-28 |
| Better Together Physician Coaching to Mitigate Burnout Amongst Clinicians Better Together Physician Coaching Program, No intervention - waitlist control - Burnout, Professional, Self Compassion | Not applicable | Completed | University of Colorado, Denver | 160 | 2023-01-02 | 2024-10-04 |
| Beyond Silence: Advancing E-mental Health Solutions to Support Canadian Healthcare Workers Beyond Silence App - Mental Health Issue, Mental Stress | Unknown | McMaster University | 50000 | 2022-11-01 | 2023-10-04 | |
| Assessing the Implementation and Feasibility of the SMART-MR Stress Management and Resilience Training - Moral Resilience (SMART-MR) program - Moral Injury | Not applicable | Completed | University of Ottawa | 98 | 2022-07-15 | 2023-01-12 |
| Frontline Clinician Psilocybin Study Psilocybin (Usona Institute), Active placebo - Burnout, Caregiver, Burnout, Professional | Phase 3 | Completed | University of Washington | 30 | 2022-03-03 | 2025-03-18 |
| Consulting After Combat: Interviewing Veterans to Develop a Therapy to Restore Functioning and Reintegration After Moral Injury Events Open pilot trial of a group therapy manual. - Moral Injury, Functional Impairment | Not applicable | Active not recruiting | VA Office of Research and Development | 14 | 2022-02-01 | 2026-04-14 |
| General Psychological Distress, PTSD, and Co-Morbidities in Healthcare Workers Consequent to Occupational Trauma Medical Music, Narrative Writing, Prolonged Exposure Therapy - Post-traumatic Stress Disorder, Moral Injury | Not applicable | Recruiting | Weill Medical College of Cornell University | 120 | 2022-01-20 | 2026-06-22 |
| Wellness Intervention for Nurses Post Traumatic Growth and Selfcare Blog writing - Trauma, Psychological, Moral Injury | Not applicable | Completed | Purdue University | 160 | 2021-11-15 | 2024-11-05 |
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Stress Disorders, Post-Traumatic (28) · Anxiety Disorders (4) · Burnout, Professional (4) · Burnout, Psychological (4) · Depression (4) · Psychological Well-Being (3) · imposter syndrome (3) · COVID-19 (2) · Brain Injuries, Traumatic (1) · Caregiver Burden (1) · Combat Disorders (1) · Compassion Fatigue (1) · Psychological Trauma (1) · Stress, Psychological (1) · Substance-Related Disorders (1)
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Adam P. McGuire, PhD (1) · Anna Harwood-Gross, PhD (1) · Anthony Back, MD (1) · Brett T. Litz, PhD (1) · Carmen Valiente, Full Porfessor (1) · Chun Lun Hsu (1) · Cindy Tofthagen, PhD (1) · Edward Spilg, MBChB (1) · Erica M. Eaton, PhD (1) · Hong Tao, PhD (1) · JoAnn Difede, PhD (1) · Lauren Borges, PhD (1) · Melissa A Wilson, PhD (1)
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I01RX002854 (1), I01RX004243 (1), I21RX002893 (1)