6 completed. 6 Phase 1, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 6 | Completed 6 |
| Phase 2 | 1 | Completed 1 |
Follow Mixed Glioma: new trials by email Literature Review of Mixed Glioma trials Research Report on Mixed Glioma
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Lapatinib Ditosylate Before Surgery in Treating Patients With Recurrent High-Grade Glioma Laboratory Biomarker Analysis, Lapatinib, Lapatinib Ditosylate - Anaplastic Astrocytoma, Anaplastic Ependymoma | Phase 1 | Completed | National Cancer Institute (NCI) | 29 | 2016-11-07 | 2024-11-06 |
| Perifosine and Torisel (Temsirolimus) for Recurrent/Progressive Malignant Gliomas Cytoreductive surgery, Perifosine, Temsirolimus - Brain Tumor, Recurrent, Glioblastoma | Phase 1 | Completed | Andrew B Lassman, MD | 10 | 2014-12-08 | 2023-05-25 |
| Vaccine Therapy and Sargramostim in Treating Patients With Malignant Glioma Laboratory Biomarker Analysis, Montanide ISA-51/Survivin Peptide Vaccine, Sargramostim - Anaplastic Astrocytoma, Anaplastic Oligoastrocytoma | Phase 1 | Completed | Roswell Park Cancer Institute | 9 | 2012-09-05 | 2017-02-27 |
| Phase I Study of Cellular Immunotherapy for Recurrent/Refractory Malignant Glioma Using Intratumoral Infusions of GRm13Z40-2, An Allogeneic CD8+ Cytolitic T-Cell Line Genetically Modified to Express the IL 13-Zetakine and HyTK and to be Resistant to Glucocorticoids, in Combination With Interleukin-2 therapeutic allogeneic lymphocytes, aldesleukin, laboratory biomarker analysis - Anaplastic Astrocytoma, Anaplastic Ependymoma | Phase 1 | Completed | City of Hope Medical Center | 6 | 2011-03-22 | 2026-10-19 |
| Viral Therapy in Treating Patients With Recurrent Glioblastoma Multiforme Carcinoembryonic Antigen-Expressing Measles Virus, Laboratory Biomarker Analysis, Therapeutic Conventional Surgery - Anaplastic Astrocytoma, Anaplastic Oligodendroglioma | Phase 1 | Completed | Mayo Clinic | 23 | 2006-10-23 | 2020-01-02 |
| Carboplatin, Melphalan, Etoposide Phosphate, Mannitol, and Sodium Thiosulfate in Treating Patients With Previously Treated Brain Tumors Carboplatin, Etoposide, Etoposide Phosphate - Anaplastic Oligoastrocytoma, Anaplastic Oligodendroglioma | Phase 1 / Phase 2 | Completed | OHSU Knight Cancer Institute | 33 | 2005-09-15 | 2022-03-17 |
Astrocytoma (6) · Glioma (6) · Oligodendroglioma (6) · Glioblastoma (5) · Brain Neoplasms (4) · Gliosarcoma (3) · Ependymoma (2) · Meningioma (1) · Neuroectodermal Tumors, Primitive (1)
Neoplasms (6) · Neoplasms by Histologic Type (6) · Neoplasms, Germ Cell and Embryonal (6) · Neoplasms, Glandular and Epithelial (6) · Neoplasms, Nerve Tissue (6) · Neoplasms, Neuroepithelial (6) · Neuroectodermal Tumors (6) · Brain Diseases (4) · Central Nervous System Diseases (4) · Central Nervous System Neoplasms (4) · Neoplasms by Site (4) · Nervous System Diseases (4) · Nervous System Neoplasms (4) · Meningeal Neoplasms (1) · Neoplasms, Vascular Tissue (1)
2-phenyl-6-(2'-(4'-(ethoxycarbonyl)thiazolyl))thiazolo(3,2-b)(1,2,4)triazole (1) · Carboplatin (1) · Colony-Stimulating Factors (1) · Cytoreduction Surgical Procedures (1) · Etoposide (1) · Interleukin-2 (1) · Interleukins (1) · Lapatinib (1) · Magnetic Resonance Spectroscopy (1) · Mannitol (1) · Melphalan (1) · N-(3-chloro-4-((3-fluorobenzyl)oxy)phenyl-6-(5-((methylsulfonyl)ethyl)aminomethyl)-2-furyl)-4-quinazolinamine (1) · aldesleukin (1) · etoposide phosphate (1) · perifosine (1)
Andrew B Lassman, MD (1) · City of Hope Medical Center (1) · Mayo Clinic (1) · National Cancer Institute (NCI) (1) · OHSU Knight Cancer Institute (1) · Roswell Park Cancer Institute (1)
United States (6)
Andrew B. Lassman, MD (1) · Behnam Badie (1) · Edward A Neuwelt (1) · Evanthia Galanis (1) · Robert Fenstermaker (1) · Timothy F Cloughesy (1)
P30CA015083 (1), P30CA016056 (1), P50CA108961 (1), U01CA137443 (1), UM1CA137443 (1)