10 completed, 3 terminated, 2 unknown, 1 not yet recruiting. 17 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 17 | Completed 10, Terminated 3, Unknown 2, Not yet recruiting 1, Withdrawn 1 |
Follow Metrorrhagia: new trials by email Literature Review of Metrorrhagia trials Research Report on Metrorrhagia
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Cyclobenzaprine for Postoperative Pain in Minimally Invasive Hysterectomy Cyclobenzaprine - Minimally Invasive Surgical Procedures, Abnormal Uterine Bleeding, Unspecified | Phase 4 | Not yet recruiting | Christiana Care Health Services | 36 | 2026-07-01 | 2026-06-24 |
| Surgical Myomectomy Followed by Oral Myfembree Versus Standard of Care Trial (SOUL) Myfembree Oral Product - Metrorrhagia, Pelvic Pain | Phase 4 | Withdrawn | University of Chicago | 2022-11-20 | 2026-06-05 | |
| Effects of a Progestin on Frequent and/or Prolonged Bleeding With Nexplanon™ Norethindrone acetate (NTA), Placebo - Birth Control, Contraception | Phase 4 | Terminated | Baylor Research Institute | 51 | 2021-02-11 | 2024-02-02 |
| Alternate Day Versus Daily Oral Iron Therapy in Adolescents Ferrous sulfate - Iron Deficiency Anemia, Heavy Menstrual Bleeding | Phase 4 | Completed | Baylor College of Medicine | 13 | 2020-12-21 | 2023-09-13 |
| Treatment of Prolonged Uterine Bleeding of Etonogestrel (ENG)-Releasing Implant Norethisterone 10mg/day, Placebo - Breakthrough Bleeding | Phase 4 | Completed | University of Sao Paulo | 114 | 2020-09-15 | 2024-09-23 |
| Use of Curcumin to Treat Unfavorable Bleeding Patterns in Contraceptive Implant Users Placebo, Curcumin - Bleeding, Implants | Phase 4 | Completed | Oregon Health and Science University | 58 | 2020-04-15 | 2024-07-03 |
| UA Versus UAE in Treatment of Fibroids Ulipristal Oral Tablet, Uterine artery embolization - Uterine Fibroid | Phase 4 | Completed | Ain Shams Maternity Hospital | 70 | 2019-03-13 | 2021-04-06 |
| Treatment of Unfavorable Bleeding Patterns in Contraceptive Implant Users Tamoxifen, Placebo, Tamoxifen (open label) - Bleeding, Implants | Phase 4 | Completed | Oregon Health and Science University | 109 | 2017-01-20 | 2020-07-15 |
| Tamoxifen to Reduce Unscheduled Bleeding in New Users of the Levonorgestrel-releasing Intrauterine System (LNG-IUS) Tamoxifen, Placebo (for Tamoxifen) - Menorrhagia, Metrorrhagia | Phase 4 | Completed | Oregon Health and Science University | 42 | 2016-09-06 | 2019-06-04 |
| Treatment of Unacceptable Bleeding Patterns in ETG Implant Users With an Oral Contraceptive EE 30mcg/LNG 150mcg, Placebo - Abnormal Uterine Bleeding, Unspecified, Uterine Bleeding Heavy | Phase 4 | Terminated | University of California, Davis | 26 | 2013-12-01 | 2017-05-12 |
| Study of a Progestin to Prevent Bleeding Associated With Initiation of Medical Menopause With GnRH Agonist Medroxyprogesterone 17-Acetate - Dysfunctional Uterine Bleeding | Phase 4 | Terminated | Kaiser Permanente | 8 | 2012-01-01 | 2015-03-17 |
| Prevention of Menstrual Migraines: Effects of Estrogen Add-back During the HFI in Patients Using Continuous Oral Contraceptives. Estradiol or Placebo - Menstrual Migraines, Menstrual Bleeding | Phase 4 | Unknown | Scott and White Hospital & Clinic | 40 | 2010-10-01 | 2010-12-01 |
| Chances for Success of CavatermTM Surgery as a Function of Uterus Probe Length Thermal Balloon Endometrial Ablation - Menorrhagia | Phase 4 | Completed | Medical University of Vienna | 290 | 2010-09-01 | 2013-03-08 |
| DMPA & High Dose Oral Progestin (MPA) Tablets in Outpatient Treatment of Acute Excessive Vaginal Bleeding Medroxyprogesterone 17-Acetate, medroxyprogesterone acetate - Dysfunctional Uterine Bleeding | Phase 4 | Completed | Women's Health Care Clinic, Torrance, California | 48 | 2009-01-01 | 2014-03-13 |
| Endometrial Ablation With Non-hysteroscopic Methods MEA, Novasure - Dysfunctional Uterine Bleeding | Phase 4 | Completed | Aristotle University Of Thessaloniki | 66 | 2008-01-01 | 2012-07-12 |
| CavatermTM vs TCRE in Women With DUB Thermal Balloon Endometrial Ablation, Transcervical Resection of the Endometrium - Dysfunctional Uterine Bleeding | Phase 4 | Unknown | Pnn Medical A/S | 158 | 2007-10-01 | 2008-05-22 |
| Evaluation of Modified Treatment Regimens for Treatment of Heavy Menstrual Bleeding Using the HerOption® System Extended treatment regimen using Her Option Cryotherapy - Menorrhagia | Phase 4 | Completed | CooperSurgical Inc. | 82 | 2004-04-01 | 2017-03-03 |
Menorrhagia (7) · Leiomyoma (3) · Hemorrhage (2) · Uterine Hemorrhage (2) · Adenomyosis (1) · Adnexal Diseases (1) · Agnosia (1) · Anemia, Iron-Deficiency (1) · Endometriosis (1) · Endometritis (1) · Headache (1) · Menstruation Disturbances (1) · Migraine Disorders (1) · Pelvic Pain (1)
Female Urogenital Diseases (17) · Female Urogenital Diseases and Pregnancy Complications (17) · Genital Diseases (17) · Genital Diseases, Female (17) · Pathologic Processes (17) · Pathological Conditions, Signs and Symptoms (17) · Urogenital Diseases (17) · Uterine Diseases (17) · Hemorrhage (15) · Uterine Hemorrhage (15) · Menstruation Disturbances (6) · Neoplasms (3) · Neoplasms by Histologic Type (3) · Neoplasms, Connective and Soft Tissue (3) · Neoplasms, Muscle Tissue (3)
Medroxyprogesterone Acetate (2) · Tamoxifen (2) · Curcumin (1) · Estradiol (1) · Ethinyl Estradiol-Norgestrel Combination (1) · Iron (1) · Iron-Dextran Complex (1) · Norethindrone (1) · Norethindrone Acetate (1) · Uterine Artery Embolization (1) · cyclobenzaprine (1) · ferrous sulfate (1) · ulipristal (1)
Oregon Health and Science University (3) · Ain Shams Maternity Hospital (1) · Aristotle University Of Thessaloniki (1) · Baylor College of Medicine (1) · Baylor Research Institute (1) · Christiana Care Health Services (1) · CooperSurgical Inc. (1) · Kaiser Permanente (1) · Medical University of Vienna (1) · Pnn Medical A/S (1) · Scott and White Hospital & Clinic (1) · University of California, Davis (1) · University of Chicago (1) · University of Sao Paulo (1) · Women's Health Care Clinic, Torrance, California (1)
United States (12) · Austria (1) · Brazil (1) · China (1) · Egypt (1) · Greece (1)
Anita L. Nelson, M.D. (1) · Beda W. Hartmann, Univ.-Doz. (1) · Carolina S Vieira, PhD, MD (1) · Jacquelyn Powers, MD (1) · Joanna Stacey, MD (1) · Malcolm Munro, MD (1) · Megan A Cohen, MD, MPH (1) · Melody Hou, MD (1) · Mitchell Creinin, MD (1) · Obianuju Sandra Madueke Laveaux, MD MPH (1) · Patricia J Sulak, MD (1) · Yanhong Yu, Prof. (1)
PMID 27419258, PMID 31226322, PMID 32649493, PMID 37116825, PMID 38954680