6 completed, 1 active not recruiting, 1 suspended. 8 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 8 | Completed 6, Active not recruiting 1, Suspended 1 |
Follow Metabolism: new trials by email Literature Review of Metabolism trials Research Report on Metabolism
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Clinical Study to Evaluate the Absorption, Metabolism, and Excretion of Oral [14C]GS1-144 in Healthy Postmenopausal Female Participants [14C]GS1-144 - Healthy Postmenopausal Women, Absorption | Phase 1 | Active not recruiting | Changchun GeneScience Pharmaceutical Co., Ltd. | 6 | 2026-04-09 | 2026-05-07 |
| Open-label Study of the Absorption, Metabolism, and Excretion of [14C]-Simufilam Following a Single Oral Dose in Healthy Male Subjects Simufilam - Absorption, Metabolism | Phase 1 | Completed | Cassava Sciences, Inc. | 8 | 2024-02-07 | 2025-03-20 |
| Study of Pharmacokinetics and Metabolism on [(14)C]ADC189 [(14)C]ADC189 - Pharmacokinetics, Metabolism | Phase 1 | Completed | Jiaxing AnDiCon Biotech Co.,Ltd | 6 | 2023-11-24 | 2025-01-20 |
| Assess the Absorption, Distribution, Metabolism and Excretion of AZD7325 After Intravenous and Oral Administration AZD7325 - Absorption, Distribution | Phase 1 | Suspended | AstraZeneca | 8 | 2009-08-01 | 2011-01-24 |
| Investigate Absorption, Metabolism and Excretion of [14C}-Proellex Following Single Oral Dose in Healthy Females Proellex - ABSORPTION, METABOLISM | Phase 1 | Completed | Repros Therapeutics Inc. | 6 | 2009-04-01 | 2014-07-08 |
| RI-AME Study OF [ISOTHIAZOLYL-3-14C]-LURASIDONE Lurasidone - Pharmacokinetics, Metabolism | Phase 1 | Completed | Sumitomo Pharma America, Inc. | 6 | 2008-08-01 | 2014-04-03 |
| Drug Interaction Study Between AZD3480 and Cytochrome P450 AZD3480, Placebo, Cocktail mix (Caffeine, Bupropion, Rosiglitazone, Omeprazole, Midazolam, Bilirubin) - Metabolism, Alzheimer's Disease | Phase 1 | Completed | AstraZeneca | 18 | 2007-11-01 | 2008-11-26 |
| -Methylenedioxymethamphetamine (MDMA, Ecstasy) Induced Changes in Drug Metabolism: Gender and Genetic Polymorphisms MDMA - Metabolism, Interaction | Phase 1 | Completed | Parc de Salut Mar | 27 | 2003-05-01 | 2011-10-06 |
Alzheimer Disease (1) · Coitus (1)
Behavior (1) · Brain Diseases (1) · Central Nervous System Diseases (1) · Dementia (1) · Mental Disorders (1) · Nervous System Diseases (1) · Neurocognitive Disorders (1) · Neurodegenerative Diseases (1) · Sexual Behavior (1) · Tauopathies (1)
4-amino-8-(2-fluoro-6-methoxy-phenyl)-N-propylcinnoline-3-carboxamide (1) · Bilirubin (1) · Bupropion (1) · Caffeine (1) · Lurasidone Hydrochloride (1) · Midazolam (1) · N-Methyl-3,4-methylenedioxyamphetamine (1) · Omeprazole (1) · Rosiglitazone (1) · Simufilam (1) · ispronicline (1) · telapristone acetate (1)
AstraZeneca (2) · Cassava Sciences, Inc. (1) · Changchun GeneScience Pharmaceutical Co., Ltd. (1) · Jiaxing AnDiCon Biotech Co.,Ltd (1) · Parc de Salut Mar (1) · Repros Therapeutics Inc. (1) · Sumitomo Pharma America, Inc. (1)
United States (3) · China (2) · Spain (1) · Sweden (1) · United Kingdom (1)
Andre van As, MD, PhD (1) · Cyril Clarke, MD (1) · John Bohn, MD (1) · Raj Chetty, MBBS, MD, FRCPath. (1)
PMID 18794647, PMID 21456632, PMID 23112822
R01DA017987 (1)