54 completed, 3 unknown, 1 active not recruiting, 1 not yet recruiting. 32 Phase 3, 21 Phase 2, 5 Phase 1, 4 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 32 | Completed 31, Active not recruiting 1 |
| Phase 2 | 21 | Completed 19, Unknown 2 |
| Phase 1 | 5 | Completed 2, Unknown 2, Not yet recruiting 1 |
| Phase 4 | 4 | Completed 4 |
Follow Meningococcal Meningitis: new trials by email Literature Review of Meningococcal Meningitis trials Research Report on Meningococcal Meningitis
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Phase Ia Clinical Trial of Group ACYW135X Meningococcal Conjugate Vaccine high-dose Group ACYW135X Meningococcal Conjugate Vaccine, medium-dose Group ACYW135X Meningococcal Conjugate Vaccine, low-dose Group ACYW135X Meningococcal Conjugate Vaccine - Meningococcal Meningitis | Phase 1 | Not yet recruiting | Sinovac Life Sciences Co., Ltd. | 150 | 2026-01-21 | 2026-01-28 |
| A Clinical Trial of ACYW135 Group Meningococcal Polysaccharide Conjugate Vaccine (CRM197 Vector) in 7 to 17 Year Olds MCV4, MPSV4 - Meningococcal Meningitis | Phase 3 | Completed | CanSino Biologics Inc. | 840 | 2024-12-14 | 2026-08-06 |
| A Study of the ACYW135 Meningococcal Polysaccharide Conjugate Vaccine ACYW135 Meningococcal Polysaccharide Conjugate Vaccine, ACYW135 Meningococcal Polysaccharide Vaccine - Meningococcal Meningitis | Phase 2 | Unknown | Aimei Vacin BioPharm (Zhejiang) Co., Ltd. | 1200 | 2024-03-20 | 2024-03-29 |
| A Clinical Trial to Evaluate the Immunogenicity and Safety of Group ACYW135 Meningococcal Conjugate Vaccine (CRM197) in Adults Aged 18 to 55 Years batch 1 of Group ACYW135 Meningococcal Conjugate Vaccine (CRM197) (MCV4), batch 2 of MCV4, batch 3 of MCV4 - Meningococcal Meningitis | Phase 3 | Completed | CanSino Biologics Inc. | 1480 | 2024-03-20 | 2026-08-06 |
| A Clinical Trial of ACYW135 Group Meningococcal Polysaccharide Conjugate Vaccine (CRM197 Vector) in 18-59 Year Olds MCV4, MPSV4 - Meningococcal Meningitis | Phase 3 | Active not recruiting | CanSino Biologics Inc. | 840 | 2024-03-01 | 2025-07-29 |
| Study to Assess Immunegnicity & Safety of Pentavalent Meningococcal Vaccine (NmCV-5) NmCV-5, Menactra - Meningococcal Meningitis | Phase 3 | Completed | Serum Institute of India Pvt. Ltd. | 1800 | 2019-08-20 | 2021-07-27 |
| Immunogenicity and Safety of an Investigational Quadrivalent Meningococcal Conjugate Vaccine in Toddlers Meningococcal Polysaccharide (Serogroups A, C, Y, and W) Tetanus Toxoid Conjugate Vaccine, Meningococcal polysaccharide groups A, C, W-135 and Y Conjugate vaccine - Meningitis, Meningococcal Meningitis | Phase 3 | Completed | Sanofi Pasteur, a Sanofi Company | 918 | 2017-02-24 | 2022-04-05 |
| Study of an Investigational Quadrivalent Meningococcal Conjugate Vaccine Administered in Children Aged 2 to 9 Years Meningococcal Polysaccharide (Serogroups A, C, Y, and W) Tetanus Toxoid Conjugate, Meningococcal (Groups A, C, Y and W 135) Oligosaccharide Diphtheria CRM197 Conjugate Vaccine - Meningitis, Meningococcal Meningitis | Phase 3 | Completed | Sanofi Pasteur, a Sanofi Company | 1000 | 2017-02-17 | 2022-03-28 |
| Immunogenicity and Safety of Meningococcal Groups A and C and Haemophilus b Conjugate Vaccine in Infants 2 to 5 Months of Age Meningococcal Groups A and C and Haemophilus b Conjugate Vaccine (adjuvant-free), Meningococcal Groups A and C and Haemophilus b Conjugate Vaccine(adjuvant) - Meningitis, Meningococcal Meningitis | Phase 1 / Phase 2 | Unknown | Beijing Zhifei Lvzhu Biopharmaceutical Co., Ltd | 360 | 2016-08-01 | 2016-09-29 |
| Postmarketing Surveillance Study for Use of Menactra® in the Republic of Korea Meningococcal (Groups A, C, Y and W 135) Polysaccharide Diphtheria Toxoid Conjugate Vaccine - Meningitis, Meningococcal Meningitis | Phase 4 | Completed | Sanofi Pasteur, a Sanofi Company | 1311 | 2016-07-21 | 2022-04-25 |
| Immune Lot Consistency, Immunogenicity, and Safety of an Investigational Quadrivalent Meningococcal Conjugate Vaccine Meningococcal Polysaccharide (Serogroups A, C, Y, and W) Tetanus Toxoid Conjugate Vaccine, Meningococcal (Groups A, C, Y and W-135) Polysaccharide Diphtheria Toxoid Conjugate Vaccine - Meningitis, Meningococcal Meningitis | Phase 3 | Completed | Sanofi Pasteur, a Sanofi Company | 3344 | 2016-07-15 | 2022-04-05 |
| Immunogenicity and Safety of an Investigational Quadrivalent Meningococcal Conjugate Vaccine in Adults 56 Years and Older Meningococcal Polysaccharide (Serogroups A, C, Y, and W) Tetanus Toxoid Conjugate Vaccine, Meningococcal Polysaccharide Vaccine, Groups A, C, Y, and W-135 Combined - Meningitis, Meningococcal Meningitis | Phase 3 | Completed | Sanofi Pasteur, a Sanofi Company | 907 | 2016-07-15 | 2022-04-05 |
| Safety of a Meningococcal (Groups A, C, Y and W-135) Polysaccharide Diphtheria Toxoid Conjugate Vaccine in Healthy Subjects in Vietnam Meningococcal (Groups A, C, Y and W-135) Polysaccharide Diphtheria Toxoid Conjugate Vaccine - Meningitis, Meningococcal Meningitis | Phase 2 | Completed | Sanofi Pasteur, a Sanofi Company | 224 | 2016-06-06 | 2018-01-08 |
| Immunogenicity and Safety of a Booster Dose of an Investigational Quadrivalent Meningococcal Conjugate Vaccine Meningococcal Polysaccharide (Serogroups A, C, Y, and W) Tetanus Toxoid Conjugate Vaccine, Meningococcal (Groups A, C, Y and W 135) Polysaccharide Diphtheria Toxoid Conjugate Vaccine - Meningitis, Meningococcal Meningitis | Phase 3 | Completed | Sanofi Pasteur, a Sanofi Company | 810 | 2016-04-15 | 2022-04-05 |
| Observational Safety Study of Menactra® Administered Under Standard Health Care Practice in the Russian Federation Meningococcal (Groups A, C, Y and W 135) Polysaccharide Diphtheria Toxoid Conjugate Vaccine - Meningitis, Meningococcal Meningitis | Completed | Sanofi Pasteur, a Sanofi Company | 100 | 2016-02-01 | 2022-04-25 | |
| Persistence of Bactericidal Antibodies in Adults Who Received a Booster Dose of Menactra® Approximately 4 Years Earlier Meningococcal (Groups A, C, Y, and W-135) Polysaccharide Diphtheria Toxoid Conjugate Vaccine - Meningitis, Meningococcal Meningitis | Phase 4 | Completed | Sanofi Pasteur, a Sanofi Company | 110 | 2015-12-01 | 2016-11-07 |
| Immunogenicity and Safety of Two-Dose Series of Menactra® in Japanese Healthy Adult Subjects Meningococcal (Groups A, C, Y and W-135) Polysaccharide Diphtheria Toxoid Conjugate - Meningitis, Meningococcal Meningitis | Phase 4 | Completed | Sanofi Pasteur, a Sanofi Company | 60 | 2015-10-20 | 2017-11-06 |
| Persistence of Protective Antibody Titers 12-24 Months After NmVac4-A/C/Y/W-135-DT Vaccination: Follow Up Study NmVac4-A/C/Y/W-135-DT™ - Meningococcal Meningitis, Meningococcal Infections | Completed | JN-International Medical Corporation | 50 | 2015-06-01 | 2016-04-12 | |
| A Single-center, Open Trials to Evaluate the Safety of Freeze-dried Group ACYW135 Meningococcal Conjugate Vaccine freeze-dried group ACYW135 MCV - Meningococcal Meningitis | Phase 1 | Unknown | Lanzhou Institute of Biological Products Co., Ltd | 200 | 2015-06-01 | 2015-06-25 |
| Immunogenicity and Safety of an Investigational Quadrivalent Meningococcal Conjugate Vaccine in Healthy Toddlers Meningococcal Polysaccharide (Serogroups A, C, Y, and W) Tetanus Toxoid Conjugate Vaccine, Meningococcal Polysaccharide groups A, C, W-135 and Y Conjugate Vaccine - Meningitis, Meningococcal Meningitis | Phase 2 | Completed | Sanofi Pasteur, a Sanofi Company | 188 | 2015-03-31 | 2022-04-04 |
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Meningococcal Vaccines (22) · MenACWY-CRM vaccine (5) · measles, mumps, rubella, varicella vaccine (3) · 4CMenB vaccine (2) · CRM197 (non-toxic variant of diphtheria toxin) (2) · Heptavalent Pneumococcal Conjugate Vaccine (2) · Vaccines (2) · Antipyretics (1) · Diphtheria Toxoid (1) · Diphtheria-Tetanus-acellular Pertussis Vaccines (1) · Haemophilus influenzae type b-polysaccharide vaccine-diphtheria toxoid conjugate (1) · Hepatitis A Vaccines (1) · Hepatitis B Vaccines (1) · HibTITER protein, Haemophilus influenzae (1) · Human Papillomavirus Recombinant Vaccine Quadrivalent, Types 6, 11, 16, 18 (1)
Novartis Vaccines (22) · Sanofi Pasteur, a Sanofi Company (18) · Novartis (4) · CanSino Biologics Inc. (3) · JN-International Medical Corporation (3) · Sanofi (2) · Aimei Vacin BioPharm (Zhejiang) Co., Ltd. (1) · Armauer Hansen Research Institute, Ethiopia (1) · Beijing Zhifei Lvzhu Biopharmaceutical Co., Ltd (1) · Lanzhou Institute of Biological Products Co., Ltd (1) · Public Health England (1) · Serum Institute of India Pvt. Ltd. (1) · Sinovac Life Sciences Co., Ltd. (1)
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