12 completed. 12 Not applicable.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 12 | Completed 12 |
Follow MDD: new trials by email Literature Review of MDD trials Research Report on MDD
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Theta Burst Stimulation for Refractory Depression in Autism Spectrum Disorder Transcranial Magnetic Stimulation, Transcranial Magnetic Stimulation Sham - ASD, Autism Spectrum Disorder | Not applicable | Completed | Children's Hospital Medical Center, Cincinnati | 20 | 2024-09-16 | 2026-10-23 |
| Extended Reality Behavioral Activation: An Intervention for Major Depressive Disorder Extended Reality-Enhanced Behavioral Activation, Traditional Behavioral Activation - Major Depressive Disorder, MDD | Not applicable | Completed | Stanford University | 26 | 2022-12-19 | 2025-09-22 |
| Individualized Neuromodulation for Anhedonic Depression Individualized Accelerated Intermittent Theta Burst Stimulation (Ind-aiTBS), Standard Accelerated Intermittent Theta Burst Stimulation (Std-aiTBS), Sham Accelerated Intermittent Theta Burst Stimulation (Sham) - MDD, Anhedonia | Not applicable | Completed | University of California, San Diego | 60 | 2022-08-01 | 2026-02-13 |
| Neurofeedback to Treat Depression Active Closed Loop Real Time fMRI Neurofeedback, Sham Closed Loop Real Time fMRI Neurofeedback - MDD | Not applicable | Completed | University of Pennsylvania | 71 | 2022-05-25 | 2025-09-08 |
| The MOOD Study - External Combined Occipital and Trigeminal Nerve Stimulation (eCOT-NS) for the Treatment of Major Depressive Disorder (MDD) Relivion®DP- Active, Relivion®DP- Sham - MDD | Not applicable | Completed | Neurolief Ltd. | 124 | 2021-08-31 | 2025-08-12 |
| Mechanism of Action of tACS for the Treatment of MDD tACS, Sham tACS - Major Depressive Disorder, MDD | Not applicable | Completed | University of North Carolina, Chapel Hill | 20 | 2021-06-09 | 2024-09-19 |
| Virtual Reality Behavioral Activation: An Intervention for Major Depressive Disorder Virtual Reality Behavioral Activation, Behavioral Activation in real-life - Major Depressive Disorder, MDD | Not applicable | Completed | Stanford University | 20 | 2020-05-18 | 2021-06-02 |
| Effect of Zinc Supplementation on Depression in SSRI-treated Major Depressive Disorder Patients SSRI with Zinc Sulfate - MDD | Not applicable | Completed | Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh | 100 | 2019-09-15 | 2021-01-27 |
| Maintenance Transcranial Magnetic Stimulation in Major Depressive Disorder TMS treatment - MDD | Not applicable | Completed | University of Missouri-Columbia | 11 | 2019-09-01 | 2023-01-04 |
| Transcranial Alternating Current Stimulation for Major Depressive Disorder tACS (alpha), tACS (gamma) - Major Depressive Disorder, MDD | Not applicable | Completed | University of North Carolina, Chapel Hill | 32 | 2015-05-07 | 2018-08-20 |
| Senior Peer Alliance for Rural Research On Wellness CM-PST, SG-PST - MDD | Not applicable | Completed | University of California, San Francisco | 105 | 2013-08-01 | 2019-07-31 |
| Can Mental Health Apps Work in the Real World? A Feasibility Pilot Study. Problem Solving Therapy, Evolution, Basic health push app - MDD | Not applicable | Completed | University of California, San Francisco | 1000 | 2013-04-01 | 2017-05-04 |
Depressive Disorder, Major (5) · Depression (3) · Anhedonia (1) · Autism Spectrum Disorder (1) · Autistic Disorder (1)
Depressive Disorder (5) · Mental Disorders (5) · Mood Disorders (5) · Behavior (3) · Behavioral Symptoms (3) · Child Development Disorders, Pervasive (1) · Nervous System Diseases (1) · Neurobehavioral Manifestations (1) · Neurodevelopmental Disorders (1) · Neurologic Manifestations (1) · Pathological Conditions, Signs and Symptoms (1) · Signs and Symptoms (1)
Transcranial Magnetic Stimulation (2) · Biological Evolution (1) · Selective Serotonin Reuptake Inhibitors (1) · Zinc Sulfate (1)
Stanford University (2) · University of California, San Francisco (2) · University of North Carolina, Chapel Hill (2) · Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh (1) · Children's Hospital Medical Center, Cincinnati (1) · Neurolief Ltd. (1) · University of California, San Diego (1) · University of Missouri-Columbia (1) · University of Pennsylvania (1)
United States (11) · Bangladesh (1) · Israel (1)
Patricia Arean, Ph.D. (2) · Brooke Hollister, Ph.D. (1) · David Rubinow, MD (1) · Flavio Frohlich, PhD (1) · Kim Bullock, M.D. (1) · Kim Bullock, MD (1) · Linda Carpenter, MD (1) · Margot D Paul, Psy.D. (1) · Margot Paul, MS (1) · Muaid Ithman, MD (1) · Rana Elmaghraby, MD (1) · Satabdi Ghosh, MBBS (1) · Yvette I Sheline, MD (1)
PMID 30093372, PMID 30123324, PMID 33031046, PMID 35404830, PMID 38437873
R01MH101547 (1), R61MH128492 (1)