5 completed, 1 recruiting, 1 unknown. 7 Phase 3, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 7 | Completed 5, Recruiting 1, Unknown 1 |
| Phase 2 | 1 | Completed 1 |
Follow Lymphatic Filariasis: new trials by email Literature Review of Lymphatic Filariasis trials Research Report on Lymphatic Filariasis
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Better Options for Lymphatic Filariasis Treatment MoxDA - Moxidectin + Diethylcarbamzine (DEC) + Albendazole, IDA - Ivermectin + DEC + albendazole - Lymphatic Filariasis, Scabies | Phase 3 | Recruiting | Medicines Development for Global Health | 5100 | 2026-09-28 | 2026-10-07 |
| Adjunctive Ivermectin Mass Drug Administration for Malaria Control Ivermectin, Placebo, Dihydroartemisinin-piperaquine - Malaria,Falciparum, Neglected Tropical Diseases | Phase 3 | Unknown | London School of Hygiene and Tropical Medicine | 24000 | 2021-05-03 | 2022-02-24 |
| Moxidectin for LF, Cote d'Ivoire (DOLF) Ivermectin, Diethylcarbamazine, Albendazole - Lymphatic Filariasis | Phase 3 | Completed | Washington University School of Medicine | 164 | 2020-08-20 | 2026-01-29 |
| A 24 Month Study to Compare Efficacy of Doxycycline vs Placebo for Improving Filarial Lymphedema in India Doxycycline, Placebo - Lymphedema, Lymphatic Filariasis | Phase 3 | Completed | The Task Force for Global Health | 235 | 2019-01-15 | 2021-06-24 |
| A 24 Month Study, to Compare the Efficacy of Doxycycline vs. Placebo for Improving Filarial Lymphedema in Mali Doxycycline, Placebo - Lymphedema, Lymphatic Filariasis | Phase 3 | Completed | The Task Force for Global Health | 220 | 2018-06-19 | 2021-06-24 |
| A 24 Month Study to Compare Efficacy of Doxycycline vs Placebo for Improving Filarial Lymphedema in Sri Lanka Doxycycline, Placebo - Lymphedema, Lymphatic Filariasis | Phase 3 | Completed | The Task Force for Global Health | 219 | 2018-02-16 | 2021-03-17 |
| Repeat Ivermectin Mass Drug Administrations for Control of Malaria: a Pilot Safety and Efficacy Study Ivermectin, Albendazole - Malaria, Lymphatic Filariasis | Phase 2 / Phase 3 | Completed | Colorado State University | 2712 | 2015-06-01 | 2019-01-04 |
Elephantiasis, Filarial (7) · Filariasis (3) · Lymphedema (3) · Malaria (2) · Scabies (2) · Strongyloidiasis (2) · Ancylostomiasis (1) · Malaria, Falciparum (1) · Neglected Diseases (1)
Helminthiasis (7) · Hemic and Lymphatic Diseases (7) · Infections (7) · Lymphatic Diseases (7) · Mosquito-Borne Diseases (7) · Nematode Infections (7) · Parasitic Diseases (7) · Secernentea Infections (7) · Spirurida Infections (7) · Vector Borne Diseases (7) · Filariasis (4) · Lymphedema (4) · Ectoparasitic Infestations (2) · Mite Infestations (2) · Protozoan Infections (2)
Albendazole (3) · Doxycycline (3) · Ivermectin (3) · Diethylcarbamazine (1) · moxidectin (1)
The Task Force for Global Health (3) · Colorado State University (1) · London School of Hygiene and Tropical Medicine (1) · Medicines Development for Global Health (1) · Washington University School of Medicine (1)
Burkina Faso (1) · Côte d’Ivoire (1) · Fiji (1) · Guinea-Bissau (1) · India (1) · Mali (1) · Sri Lanka (1) · United States (1)
Eric Ottesen, MD (3) · Anna R Last, MBChB PhD (1) · Benjamin Koudou, PhD (1) · Brian D. Foy, PhD (1) · Catherine Bjerum, MD, MPH (1) · Philip Budge, MD, PhD (1) · Roch K Dabire, PhD (1) · Toki Pascal Gabo, MD (1)
PMID 11873261, PMID 22610930, PMID 32228663, PMID 10656038, PMID 30878222, PMID 37419638, PMID 37616301, PMID 37721964, PMID 39551062, PMID 40345209, PMID 42848323