5 completed, 4 recruiting, 1 active not recruiting, 1 unknown. 3 Not applicable.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 3 | Completed 2, Recruiting 1 |
Follow Loeys-Dietz Syndrome: new trials by email Literature Review of Loeys-Dietz Syndrome trials Research Report on Loeys-Dietz Syndrome
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| PregnAncy-Related Aortic DISsEction in China Intervention strategies including medication or surgery - Pregnancy Complication, Aortic Dissection | Recruiting | DeltaHealth Hospital · Shanghai | 500 | 2026-03-17 | 2026-07-17 | |
| National Network for Cardiovascular Genomics: Advancing Cardiovascular Healthcare for Hereditary Diseases in Brazil's Unified Health System Through a Multicenter Registry whole genome sequencing - Cardiomyopathy, Hypertrophic, Cardiomyopathy, Dilated | Recruiting | Hospital do Coracao | 1211 | 2025-04-30 | 2026-05-08 | |
| Single-Session "Empowered Relief" Class for Marfan Syndrome and Related Conditions Empowered Relief - Chronic Pain, Marfan Syndrome | Not applicable | Completed | Stanford University | 92 | 2024-03-21 | 2024-10-26 |
| Proximal Aortopathy in Scotland - Epidemiology and Surgical Outcomes Surgery on the proximal aorta (aortic root +/- ascending aorta), Patients diagnosed with thoracic aortopathy but not operated upon - Aortic Diseases, Aortic Dissection | Unknown | Golden Jubilee National Hospital | 1662 | 2023-12-18 | 2024-07-15 | |
| Immunopathology of Loeys-Dietz Syndrome blood samples - Loeys-Dietz Syndrome | Not applicable | Completed | Hospices Civils de Lyon | 60 | 2022-10-17 | 2023-06-09 |
| Pathogenetic Basis of Aortopathy and Aortic Valve Disease Aortopathies, Thoracic Aortic Aneurysm | Active not recruiting | Yale University | 3000 | 2015-12-10 | 2026-02-13 | |
| Natural History and Genetics of Food Allergy and Related Conditions Food Allergy, Loeys-Dietz Syndrome | Recruiting | National Institute of Allergy and Infectious Diseases (NIAID) | 1800 | 2015-07-29 | 2026-10-13 | |
| Micro RNAs as a Marker of Aortic Aneurysm in Hereditary Aortopathy Syndromes Marfan Syndrome, Loeys-Dietz Syndrome | Completed | University of Colorado, Denver | 20 | 2014-07-01 | 2017-03-15 | |
| Complex Aortic Aneurysm Repair Using Physician Modified Endografts and Custom Made Devices Custom Made Fenestrated or Branched Stent Graft - Complex Aortic Aneurysms, Thoracoabdominal Aneurysms | Not applicable | Recruiting | Andres Schanzer | 600 | 2014-03-01 | 2025-10-22 |
| Genotypes and Craniofacial Phenotypes in Orthodontic Patients With Marfan and Loeys-Dietz Syndromes Cephalometric analysis - Marfan Syndrome, Loeys-Dietz Syndrome | Completed | Andrea Scribante | 39 | 2012-07-07 | 2026-01-22 | |
| National Registry of Genetically Triggered Thoracic Aortic Aneurysms and Cardiovascular Conditions Marfan Syndrome, Turner Syndrome | Completed | National Heart, Lung, and Blood Institute (NHLBI) | 3706 | 2007-11-01 | 2016-12-20 |
Marfan Syndrome (9) · Ehlers-Danlos Syndrome, Type IV (5) · Aortic Dissection (4) · Aortic Aneurysm, Thoracic (3) · Bicuspid Aortic Valve Disease (3) · Ehlers-Danlos Syndrome (3) · Turner Syndrome (3) · Aortic Aneurysm, Familial Thoracic 1 (2) · Shprintzen Golberg craniosynostosis (2) · Aneurysm (1) · Aneurysm, Aortic Arch (1) · Aneurysm, Ascending Aorta (1) · Aortic Aneurysm (1) · Aortic Aneurysm, Abdominal (1)
Abnormalities, Multiple (11) · Cardiovascular Diseases (11) · Congenital Abnormalities (11) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (11) · Craniofacial Abnormalities (11) · Genetic Diseases, Inborn (11) · Musculoskeletal Abnormalities (11) · Musculoskeletal Diseases (11) · Vascular Diseases (11) · Aneurysm (10) · Aortic Aneurysm (10) · Aortic Diseases (10) · Bone Diseases (10) · Bone Diseases, Developmental (10) · Skin and Connective Tissue Diseases (10)
Blood Specimen Collection (1) · Surgical Procedures, Operative (1)
Andrea Scribante (1) · Andres Schanzer (1) · DeltaHealth Hospital · Shanghai (1) · Golden Jubilee National Hospital (1) · Hospices Civils de Lyon (1) · Hospital do Coracao (1) · National Heart, Lung, and Blood Institute (NHLBI) (1) · National Institute of Allergy and Infectious Diseases (NIAID) (1) · Stanford University (1) · University of Colorado, Denver (1) · Yale University (1)
United States (6) · Brazil (1) · China (1) · France (1) · Italy (1) · United Kingdom (1)
Andrea Scribante, DDS, PhD (1) · Andres Schanzer, MD (1) · Barbara Kroner, PhD, MPH (1) · Benjamin Landis, MD (1) · Beth Darnall, PhD (1) · Cheryl L. Maslen, Ph.D. (1) · Dianna M. Milewicz, M.D. Ph.D. (1) · Federico M. Asch, MD,FACC,FASE (1) · George Gradinariu, MD (1) · Jennifer Habashi, MD (1) · Kathryn C Chatfield, MD, PhD (1) · Kim Eagle, M.D. (1) · Pamela A Frischmeyer-Guerrerio, M.D. (1) · Ralph Shohet, MD (1) · Reed E. Pyeritz, M.D., Ph.D. (1)
PMID 19699898, PMID 21982653, PMID 22104675, PMID 23444191, PMID 25595400, PMID 32249045, PMID 36384183, PMID 37059239, PMID 37330702, PMID 38989575, PMID 39963789, PMID 41495090, PMID 42155862
268201000048C-5-0-1 (1), N01HV681997 (1), UL1TR001082 (1)