5 completed, 4 unknown, 1 withdrawn. 2 Not applicable, 2 Phase 1, 1 Early Phase 1, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 2 | Completed 2 |
| Phase 1 | 2 | Unknown 1, Withdrawn 1 |
| Early Phase 1 | 1 | Unknown 1 |
| Phase 2 | 1 | Unknown 1 |
Follow Liver Failure, Acute on Chronic: new trials by email Literature Review of Liver Failure, Acute on Chronic trials Research Report on Liver Failure, Acute on Chronic
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| MSC-EV in Acute-on-Chronic Liver Failure After Liver Transplantation MSC-EV - Liver Failure, Acute on Chronic | Phase 1 | Withdrawn | Third Affiliated Hospital, Sun Yat-Sen University | 2023-09-30 | 2023-10-12 | |
| The Efficacy and Safety of Rifaximin Treatment Rifaximin 200 mg, Standard Treatment without Rifaximin - Liver Failure, Acute on Chronic, Hepatic Encephalopathy | Early Phase 1 | Unknown | Sun Yat-sen University | 124 | 2023-03-09 | 2023-03-28 |
| S100A8/A9 and Innate Immunity in Liver Disease Cirrhosis, Liver, Immune Suppression | Unknown | St George's, University of London | 100 | 2021-09-28 | 2023-03-31 | |
| Safety and Efficacy of Mesenchymal Stem Cell Transplantation for Acute-on-Chronic Liver Failure Mesenchymal Stem Cell - Liver Failure, Acute on Chronic | Phase 1 / Phase 2 | Unknown | Tianjin Weikai Bioeng., Ltd. | 45 | 2019-10-01 | 2019-03-20 |
| Citrate Pharmacokinetics in Critically Ill Liver Failure Patients Receiving CRRT Pharmacokinetic study - Citrate Toxicity, Regional Citrate Anticoagulation | Not applicable | Completed | Chulalongkorn University | 20 | 2019-07-01 | 2022-11-14 |
| A Validation Cohort for ACLF Diagnosis and Prognosis Standary therapy - Liver Failure, Acute on Chronic, Liver Dysfunction | Completed | Hai Li | 1370 | 2018-09-20 | 2020-10-22 | |
| A Prospective Study of Evaluation of Minor Bleeding and Utility of Bleeding Criteria in Acute-on-chronic Liver Failure Patients in China Liver Failure, Acute on Chronic, Hemostatic Disorder | Unknown | Nanfang Hospital, Southern Medical University | 100 | 2017-04-16 | 2017-09-13 | |
| Chinese CLIF-C Acute-on-Chronic Liver Disease and Liver Failure Study Standary therapy - Liver Failure, Acute on Chronic | Completed | Hai Li | 2600 | 2015-01-01 | 2020-08-11 | |
| HEpatic Regeneration With COupled Plasma Filtration and Adsorption for Liver Extracorporeal Detoxification Coupled plasma filtration and adsorption (CPFA) - Liver Failure, Acute, Liver Failure, Acute on Chronic | Not applicable | Completed | IRCCS Azienda Ospedaliero-Universitaria di Bologna | 12 | 2013-06-06 | 2021-03-17 |
| A Retrospective Multicenter Study of HBV-related Pre-acute-on-chronic Liver Failure in China standard treatment - Liver Failure, Acute on Chronic, Liver Injury | Completed | Nanfang Hospital, Southern Medical University | 1178 | 2012-01-01 | 2018-01-23 |
Acute-On-Chronic Liver Failure (10) · Liver Failure (3) · Fibrosis (2) · Hepatitis B (2) · Liver Failure, Acute (2) · Multiple Organ Failure (2) · Hemostatic Disorders (1) · Hepatic Encephalopathy (1) · Infections (1) · Liver Cirrhosis (1) · Liver Diseases (1)
Digestive System Diseases (10) · Hepatic Insufficiency (10) · Liver Diseases (9) · Liver Failure, Acute (8) · Liver Failure (7) · Pathologic Processes (4) · Pathological Conditions, Signs and Symptoms (4) · Blood-Borne Infections (2) · Communicable Diseases (2) · DNA Virus Infections (2) · Hepadnaviridae Infections (2) · Hepatitis (2) · Hepatitis, Viral, Human (2) · Infections (2) · Shock (2)
Rifaximin (1)
Hai Li (2) · Nanfang Hospital, Southern Medical University (2) · Chulalongkorn University (1) · IRCCS Azienda Ospedaliero-Universitaria di Bologna (1) · St George's, University of London (1) · Sun Yat-sen University (1) · Third Affiliated Hospital, Sun Yat-Sen University (1) · Tianjin Weikai Bioeng., Ltd. (1)
China (6) · Italy (1) · Thailand (1) · United Kingdom (1)
Hai Li (2) · Arjuna Singanayagam, MBBS; PhD (1) · Gaetano La Manna, Prof. (1) · Yang Yang, PHD, MD (1)
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