9 completed, 4 unknown, 3 recruiting, 2 terminated. 8 Not applicable, 2 Phase 2, 2 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 8 | Completed 6, Recruiting 1, Unknown 1 |
| Phase 2 | 2 | Completed 2 |
| Phase 3 | 2 | Completed 1, Recruiting 1 |
Follow Lichen Sclerosus: new trials by email Literature Review of Lichen Sclerosus trials Research Report on Lichen Sclerosus
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A 52-Week Trial to Investigate the Efficacy and Safety of Delgocitinib Cream in Adult Participants With Lichen Sclerosus Delgocitinib, Cream Vehicle - Lichen Sclerosus | Phase 3 | Recruiting | LEO Pharma | 652 | 2026-05-01 | 2026-10-13 |
| Male Lichen Sclerosus - Risk Factors, Treatment, and Impact on Quality of Life Circumcision - Lichen Sclerosus | Recruiting | Region Västerbotten | 300 | 2025-10-06 | 2026-02-10 | |
| Vaginal Ecosystem and Network in the United States Study Vaginal Swab Collection - Bacterial Vaginosis, Candidiasis | Enrolling by invitation | Vaginal Biome Science | 3250 | 2024-05-16 | 2025-07-01 | |
| Comparison of Laser Treatment With Clobetasol Therapy in Patients With Lichen Sclerosus Treatment with Monalisa Glide Laser, Treatment with Clobetasol - Lichen Sclerosus | Not applicable | Recruiting | Kantonsspital Winterthur KSW | 120 | 2023-11-10 | 2025-09-23 |
| A Study to Evaluate the Efficacy and Safety of Ruxolitinib Cream in Participants With Lichen Sclerosus Ruxolitinib cream, Vehicle cream - Lichen Sclerosus | Phase 2 | Completed | Incyte Corporation | 61 | 2022-11-18 | 2024-09-24 |
| Genital Lichen Sclerosus - Epidemiology, Comorbidities and the Role of Vulvar and Penile Microbiome Lichen Sclerosus | Unknown | Region Jönköping County | 200 | 2022-01-14 | 2023-01-09 | |
| Laser vs Clobetasol for Lichen Sclerosus Clobetasol 0.05% Emollient Top Cream, Non-ablative CO2 Laser - Lichen Sclerosus | Phase 3 | Completed | Ruhr University of Bochum | 246 | 2021-11-02 | 2025-12-04 |
| Safety and Efficacy of Laser Therapy in Gynaecology Herpes Genitalis, Genital Wart | Unknown | Juna d.o.o. | 300 | 2019-07-24 | 2019-08-30 | |
| MonaLisa Touch Laser for the Treatment of Vulvar Lichen Sclerosus FxCO2 Laser, Sham Laser - Lichen Sclerosus | Not applicable | Completed | Center for Vulvovaginal Disorders | 40 | 2018-08-28 | 2020-11-12 |
| a Flexible Wound Dressing for the Management of Genital Skin Conditions Film forming silicone gel (7-0940) - Vaginitis, Atrophic Vaginitis | Not applicable | Completed | Stratpharma AG | 54 | 2018-01-31 | 2022-05-31 |
| Lichen Sclerosus - the Influence on Quality of Life Standard care and sexological counseling - Lichen Sclerosus | Not applicable | Completed | Regionshospital Nordjylland | 158 | 2018-01-04 | 2020-05-27 |
| Biomarkers of Lichen Sclerosus Lichen Sclerosus | Unknown | Center for Vulvovaginal Disorders | 58 | 2017-11-27 | 2018-06-19 | |
| Fractional / Pixel CO2 Laser Treatment of Vulvar Atrophy and Lichen Sclerosus Fractional / Pixel CO2 Laser - Vaginal Atrophy, Lichen Sclerosus | Not applicable | Completed | Hadassah Medical Organization | 16 | 2017-09-01 | 2019-08-06 |
| Vulvar Mucosal Specialty Clinic Chart Review Vulvar Disease, Lichen Sclerosus | Terminated | Northwestern University | 719 | 2016-04-01 | 2020-10-09 | |
| Vulvar Scarring Grading Scale for Lichen Sclerosus Photography - Lichen Sclerosus, Lichen Sclerosus et Atrophicus | Terminated | Northwestern University | 30 | 2016-03-01 | 2020-10-09 | |
| Nd:Yttrium Aluminum Garnet Laser Treatment for Lichen Sclerosus Nd:YAG Laser, Topical corticosteroid Diprosone - Lichen Sclerosus, Lichen Sclerosus Et Atrophicus | Not applicable | Unknown | Dr Adolf Lukanovič | 40 | 2016-01-28 | 2018-05-15 |
| Evaluation of the Role of Vibrational Spectroscopy in the Assessment of Vulval Disease Normal Vulval Skin, Lichen Sclerosus | Suspended | Gloucestershire Hospitals NHS Foundation Trust | 200 | 2014-08-01 | 2017-08-04 | |
| Platelet Rich Plasma Injections for Vulvar Lichen Sclerosus Autologous platelet rich plasma - Lichen Sclerosus | Not applicable | Completed | Center for Vulvovaginal Disorders | 15 | 2014-05-01 | 2016-06-09 |
| Diagnostic Accuracy of "Three Rings Vulvoscopy" for Detection of Vulvar Dermatosis "Three Rings Vulvoscopy" (TRIV), Histopathology - Lichen Sclerosus, Lichen Planus | Not applicable | Completed | Ginekološka Poliklinika Dr. Vesna Harni | 328 | 2011-12-01 | 2019-10-30 |
| Clobetasol Versus Pimecrolimus for Vulvar Lichen Sclerosus pimecrolimus and clobetasol, clobetasol 0.05% cream - Lichen Sclerosus | Phase 2 | Completed | Center for Vulvovaginal Disorders | 38 | 2006-10-01 | 2014-05-12 |
Lichen Sclerosus et Atrophicus (20) · Lichen Planus (4) · Vulvar Diseases (4) · Vulvodynia (3) · Neoplasms (2) · Vulvar Neoplasms (2) · Atrophic Vaginitis (1) · Candidiasis (1) · Carcinoma, Squamous Cell (1) · Condylomata Acuminata (1) · Disease (1) · Endometriosis (1) · Herpes Genitalis (1) · Hidradenitis Suppurativa (1) · Neurodermatitis (1)
Lichenoid Eruptions (20) · Skin Diseases, Papulosquamous (20) · Skin and Connective Tissue Diseases (20) · Skin Diseases (19) · Female Urogenital Diseases (8) · Female Urogenital Diseases and Pregnancy Complications (8) · Genital Diseases (8) · Genital Diseases, Female (8) · Urogenital Diseases (8) · Male Urogenital Diseases (3) · Bacterial Infections (2) · Bacterial Infections and Mycoses (2) · Genital Diseases, Male (2) · Genital Neoplasms, Female (2) · Infections (2)
Clobetasol (3) · Circumcision, Male (1) · Lasers, Solid-State (1) · Photography (1) · Standard of Care (1) · Therapeutics (1) · delgocitinib (1) · pimecrolimus (1)
Center for Vulvovaginal Disorders (4) · Northwestern University (2) · Dr Adolf Lukanovič (1) · Ginekološka Poliklinika Dr. Vesna Harni (1) · Gloucestershire Hospitals NHS Foundation Trust (1) · Hadassah Medical Organization (1) · Incyte Corporation (1) · Juna d.o.o. (1) · Kantonsspital Winterthur KSW (1) · LEO Pharma (1) · Region Jönköping County (1) · Region Västerbotten (1) · Regionshospital Nordjylland (1) · Ruhr University of Bochum (1) · Stratpharma AG (1)
United States (8) · Canada (3) · Sweden (2) · United Kingdom (2) · Australia (1) · Croatia (1) · Denmark (1) · Germany (1) · Israel (1) · Slovenia (1) · Switzerland (1)
Andrew T Goldstein, MD (2) · Bethanee J Schlosser, MD, PhD (2) · Andrew Goldstein, MD (1) · Annika Bergman, PhD (1) · Charles Macri, MD (1) · Clemens B Tempfer, MD (1) · Gesine Meili, MD (1) · Haq Nawaz, MD (1) · Kimberly Capone, PhD (1) · Linda Berglind (1) · Oliver Seifert, PhD AssProf (1)
PMID 12418071, PMID 15568399, PMID 16130842, PMID 16176512, PMID 20522071, PMID 20868406, PMID 21353334, PMID 25608255, PMID 33957648, PMID 35333024, PMID 39035147, PMID 42208069
2025 (1)