13 completed, 3 unknown, 2 recruiting, 2 terminated. 8 Not applicable, 5 Phase 2, 3 Early Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 8 | Completed 2, Recruiting 2, Unknown 2, Suspended 1, Withdrawn 1 |
| Phase 2 | 5 | Completed 2, Terminated 2, Unknown 1 |
| Early Phase 1 | 3 | Completed 3 |
Follow Larynx: new trials by email Literature Review of Larynx trials Research Report on Larynx
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Prevalence of EILO Among Children With Asthma Continuous Laryngoscopy during Exercise Test (CLE test) - Exercise Induced Laryngeal Obstruction, Asthma in Children | Not applicable | Unknown | Medisch Spectrum Twente | 200 | 2024-08-01 | 2024-06-28 |
| Voice Outcome of Glottoplasty, Cricothyroid Approximation, Thyroplasty, and Chondrolaryngoplasty Phonosurgery, Mastectomy/breast augmentation - Surgery, Larynx | Not applicable | Recruiting | University Ghent | 290 | 2024-04-10 | 2024-06-03 |
| Laryngeal Allograft Transplantation Larynx Allograft Transplantation - Larynx Stenosis, Larynx Disease | Not applicable | Suspended | Mayo Clinic | 10 | 2023-05-19 | 2026-07-22 |
| Ultrasound Assessment of the Larynx and Trachea in the Neonatal Period Larynx and trachea ultrasound - Larynx, Trachea | Completed | Princess Anna Mazowiecka Hospital, Warsaw, Poland | 300 | 2022-06-14 | 2024-08-14 | |
| Teach Intubation by Novices in Anaesthesiology Videolarygoscopy, conventional laryngoscopy - Learning Problem, Larynx | Not applicable | Unknown | Johannes Gutenberg University Mainz | 10 | 2021-12-02 | 2023-01-25 |
| Bilateral Elective Neck Dissection in Salvage Total Laryngectomy Elective bilateral neck dissection in cN0 patients - Neck Cancer, Larynx | Completed | Fondazione Policlinico Universitario Agostino Gemelli IRCCS | 80 | 2020-09-01 | 2023-02-28 | |
| Durvalumab With Radiotherapy for Adjuvant Treatment of Intermediate Risk SCCHN Durvalumab, Intensity Modulated Radiotherapy Treatments - Larynx, Lip | Phase 2 | Completed | UNC Lineberger Comprehensive Cancer Center | 18 | 2019-10-07 | 2026-10-22 |
| Nivolumab and BMS986205 in Treating Patients With Stage II-IV Squamous Cell Cancer of the Head and Neck Nivolumab, IDO1 Inhibitor BMS-986205, Therapeutic Conventional Surgery - Lip, Oral Cavity Squamous Cell Carcinoma | Phase 2 | Terminated | Thomas Jefferson University | 65 | 2019-04-09 | 2026-10-19 |
| CLE During Exercise Testing in Asthma Continuous laryngoscopy during exercise test - Larynx, Obstruction | Not applicable | Withdrawn | Helsinki University Central Hospital | 2019-03-01 | 2022-07-07 | |
| Window of Opportunity Trial of Durvalumab (MEDI4736) or Durvalumab/Tremelimumab as Neoadjuvant Chemotherapy to Identify Immune Dynamics in Surgically Resectable Head and Neck Cancer Patients. Durvalumab, durvalumab + tremelimumab - Stage II-IVB Operable HNSCC Oral Cavity, Hypopharynx | Phase 2 | Unknown | Yonsei University | 48 | 2019-01-02 | 2023-03-21 |
| Vocal Cord Responses During Hyperventilation in Normal Individuals and in Mild and Severe Asthmatics. Acute Hyperventilation, Chronic hyperventilation, Effects of anticholinergic medication - Hyperventilation, Larynx | Completed | Monash Medical Centre | 24 | 2018-06-01 | 2025-05-08 | |
| Accuracy of the Sensory Test Using the Laryngopharyngeal Endoscopic Esthesiometer in Obstructive Sleep Apnea Laryngopharyngeal sensory test - Sleep Apnea, Obstructive, Larynx | Not applicable | Recruiting | Fundación Neumologica Colombiana | 117 | 2018-01-01 | 2026-01-08 |
| Window of Opportunity Trial of Nivolumab and Tadalafil in Patients With Squamous Cell Carcinoma of the Head and Neck Nivolumab, Tadalafil, Therapeutic Conventional Surgery - Lip, Oral Cavity and Pharynx, Larynx | Early Phase 1 | Completed | Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University | 50 | 2017-08-10 | 2025-04-29 |
| The Efficacy of Capsaicin Sensitivity Testing in Patients With Irritable Larynx Syndrome Capsaicin cough challenge test - Cough, Larynx | Withdrawn | Unity Health Toronto | 2017-08-01 | 2017-08-01 | ||
| Nivolumab, Ipilimumab, and Radiation Therapy in Treating Patients With Stage III-IVB Head and Neck Cancer Nivolumab, Ipilimumab, Simultaneous-Integrated Boost Intensity-Modulated Radiation Therapy - Larynx, Lip, Oral Cavity and Pharynx | Early Phase 1 | Completed | Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University | 24 | 2017-05-11 | 2025-04-29 |
| Metformin Hydrochloride and Doxycycline in Treating Patients With Head and Neck Squamous Cell Carcinoma Metformin Hydrochloride, Doxycycline, Metformin +Doxycycline - Larynx, LIP | Phase 2 | Terminated | Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University | 7 | 2017-04-03 | 2026-01-29 |
| Metformin Hydrochloride in Affecting Cytokines and Exosomes in Patients With Head and Neck Cancer External Beam Radiation Therapy, Metformin Hydrochloride, Placebo - Larynx, Lip | Early Phase 1 | Completed | Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University | 9 | 2017-01-05 | 2025-04-30 |
| Relationship of Cricoid With the Right and Left Bronchial Diameters in the Pediatric Population Using Three-dimensional Imaging. Larynx, Oxygen | Completed | King Fahad Medical City | 35 | 2016-08-01 | 2017-01-25 | |
| Innervation of Human Cricopharyngeal Muscle By Recurrent Laryngeal and External Branch of Superior Laryngeal Nerve The NIM 3.0 Nerve Monitoring System - Larynx | Not applicable | Completed | Sisli Hamidiye Etfal Training and Research Hospital | 100 | 2015-02-01 | 2016-05-04 |
| A Study of Chemo +/- Low-dose Radiation as Induction Therapy in SCCHN Low dose fractionated radiation - 80cGy with chemotherapy, Docetaxel and Carboplatin AUC 6 - Head and Neck Cancer, Larynx | Phase 2 | Completed | Susanne Arnold | 45 | 2014-10-01 | 2023-03-13 |
Showing 20 of 23. Sign in to see all of them.
Laryngeal Diseases (23) · Lymphoid Interstitial Pneumonia (5) · Carcinoma, Squamous Cell (2) · Head and Neck Neoplasms (2) · Squamous Cell Carcinoma of Head and Neck (2) · Asthma (1) · Asthma, Exercise-Induced (1) · Bites and Stings (1) · Cough (1) · Disease (1) · Dyspnea (1) · Gender Dysphoria (1) · Hyperventilation (1) · Laryngeal Neoplasms (1) · Laryngostenosis (1)
Otorhinolaryngologic Diseases (23) · Respiratory Tract Diseases (23) · Neoplasms by Site (5) · Respiration Disorders (5) · Neoplasms (4) · Pathological Conditions, Signs and Symptoms (4) · Signs and Symptoms (4) · Head and Neck Neoplasms (3) · Signs and Symptoms, Respiratory (3) · Bronchial Diseases (2) · Carcinoma (2) · Hypersensitivity (2) · Hypersensitivity, Immediate (2) · Immune System Diseases (2) · Neoplasms by Histologic Type (2)
Nivolumab (3) · Metformin (2) · durvalumab (2) · CTLA-4 Antigen (1) · Docetaxel (1) · Doxycycline (1) · Drug Therapy (1) · Ipilimumab (1) · Laryngoplasty (1) · Mastectomy (1) · Radiotherapy, Intensity-Modulated (1) · Tadalafil (1) · linrodostat (1) · tremelimumab (1)
Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University (4) · Fondazione Policlinico Universitario Agostino Gemelli IRCCS (1) · Fundación Neumologica Colombiana (1) · Helsinki University Central Hospital (1) · Icahn School of Medicine at Mount Sinai (1) · Johannes Gutenberg University Mainz (1) · King Fahad Medical City (1) · Mayo Clinic (1) · Medisch Spectrum Twente (1) · Monash Medical Centre (1) · National Medical Center, Seoul (1) · Princess Anna Mazowiecka Hospital, Warsaw, Poland (1) · Sisli Hamidiye Etfal Training and Research Hospital (1) · Susanne Arnold (1) · Thomas Jefferson University (1)
United States (10) · Australia (1) · Belgium (1) · Canada (1) · Colombia (1) · Finland (1) · Germany (1) · Italy (1) · Netherlands (1) · Poland (1) · South Korea (1)
Adam Luginbuhl, MD (3) · Jennifer Johnson, MD, PhD (2) · Andrew Sikora, MD, PhD (1) · Brian P Radesic, DNP, CRNA (1) · Clara Leyns, PhD (1) · David G Lott, MD (1) · Evelien D'haeseleer, PhD (1) · Jennifer Anderson, MD, FRCS(C) (1) · Laurence Ruane, BSc (1) · Luis F Giraldo-Cadavid, MD, PhD (1) · Marc MK Kriege, PD Dr (1) · Mehmet Uludag, Professor (1) · Mija Yun (1) · Paula Kauppi, MD, PhD (1) · Peter Tomassen, PhD, MD (1)
PMID 19815444, PMID 21477778, PMID 24355831, PMID 28827237, PMID 34911681, PMID 37019367, PMID 37174969, PMID 37536941, PMID 38857913, PMID 40634702, PMID 41045934, PMID 41555932, PMID 8870349