2 completed, 2 terminated, 1 unknown. 5 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 5 | Completed 2, Terminated 2, Unknown 1 |
Follow Larynx: new trials by email Literature Review of Larynx trials Research Report on Larynx
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Durvalumab With Radiotherapy for Adjuvant Treatment of Intermediate Risk SCCHN Durvalumab, Intensity Modulated Radiotherapy Treatments - Larynx, Lip | Phase 2 | Completed | UNC Lineberger Comprehensive Cancer Center | 18 | 2019-10-07 | 2026-10-22 |
| Nivolumab and BMS986205 in Treating Patients With Stage II-IV Squamous Cell Cancer of the Head and Neck Nivolumab, IDO1 Inhibitor BMS-986205, Therapeutic Conventional Surgery - Lip, Oral Cavity Squamous Cell Carcinoma | Phase 2 | Terminated | Thomas Jefferson University | 65 | 2019-04-09 | 2026-10-19 |
| Window of Opportunity Trial of Durvalumab (MEDI4736) or Durvalumab/Tremelimumab as Neoadjuvant Chemotherapy to Identify Immune Dynamics in Surgically Resectable Head and Neck Cancer Patients. Durvalumab, durvalumab + tremelimumab - Stage II-IVB Operable HNSCC Oral Cavity, Hypopharynx | Phase 2 | Unknown | Yonsei University | 48 | 2019-01-02 | 2023-03-21 |
| Metformin Hydrochloride and Doxycycline in Treating Patients With Head and Neck Squamous Cell Carcinoma Metformin Hydrochloride, Doxycycline, Metformin +Doxycycline - Larynx, LIP | Phase 2 | Terminated | Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University | 7 | 2017-04-03 | 2026-01-29 |
| A Study of Chemo +/- Low-dose Radiation as Induction Therapy in SCCHN Low dose fractionated radiation - 80cGy with chemotherapy, Docetaxel and Carboplatin AUC 6 - Head and Neck Cancer, Larynx | Phase 2 | Completed | Susanne Arnold | 45 | 2014-10-01 | 2023-03-13 |
Laryngeal Diseases (5) · Lymphoid Interstitial Pneumonia (2) · Carcinoma, Squamous Cell (1) · Head and Neck Neoplasms (1) · Mouth Neoplasms (1) · Neoplasms (1) · Squamous Cell Carcinoma of Head and Neck (1)
Otorhinolaryngologic Diseases (5) · Respiratory Tract Diseases (5) · Neoplasms by Site (3) · Head and Neck Neoplasms (2) · Neoplasms (2) · Carcinoma (1) · Mouth Diseases (1) · Neoplasms by Histologic Type (1) · Neoplasms, Glandular and Epithelial (1) · Neoplasms, Squamous Cell (1) · Stomatognathic Diseases (1)
durvalumab (2) · Docetaxel (1) · Doxycycline (1) · Drug Therapy (1) · Metformin (1) · Nivolumab (1) · linrodostat (1) · tremelimumab (1)
Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University (1) · Susanne Arnold (1) · Thomas Jefferson University (1) · UNC Lineberger Comprehensive Cancer Center (1) · Yonsei University (1)
United States (4) · South Korea (1)
Adam Luginbuhl, MD (1) · Jennifer Johnson, MD, PhD (1) · Siddharth Sheth, DO MPH (1) · Susanne M Arnold, MD (1)