9 completed, 5 unknown, 2 recruiting, 2 terminated. 20 Phase 3, 2 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 20 | Completed 9, Unknown 5, Recruiting 2, Terminated 2, Withdrawn 2 |
| Phase 2 | 2 | Completed 2 |
Follow Kidney Calculi: new trials by email Literature Review of Kidney Calculi trials Research Report on Kidney Calculi
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Trial to Assess the Efficacy of EMPAgliflozin and Personalized Dietary Counseling for Kidney STONE Prevention Empagliflozin 10 MG, Placebo, Personalized dietary counseling - Kidney Stone, Nephrolithiasis | Phase 3 | Recruiting | Insel Gruppe AG, University Hospital Bern | 400 | 2026-07-02 | 2026-10-23 |
| Impact of Forced Diuresis on the Residual Fragment Rate After Flexible Ureteroscopy for Destruction of Kidney Stones With Laser Furosemide 40 mg - Kidney Stone | Phase 3 | Recruiting | University Hospital, Tours | 374 | 2024-01-04 | 2025-11-24 |
| Ultra-Mini Versus Standard Percutaneous Nephrolithotomy For Management Of Renal Calculi. A Randomized Controlled Trial. percutaneous nephrolithotomy, ultra-mini percutaneous nephrolithotomy - Stone, Kidney | Phase 3 | Unknown | Ain Shams University | 60 | 2021-02-28 | 2021-02-21 |
| Holmium Vs Trilogy Kidney Stones GUY's 1-2 Fragmentation of calculi with 100 W Holmium laser or LithoClast Trilogy EMS and 1.5 mm x 440 mm probe, according to randomization. - Kidney Stone, Kidney Calculi | Phase 3 | Unknown | Hospital Regional de Alta Especialidad del Bajio | 116 | 2020-09-30 | 2020-09-22 |
| Perioperative Pregabalin in Ureteroscopy Pregabalin 300mg, Placebo oral tablet - Kidney Stone, Pain, Postoperative | Phase 2 / Phase 3 | Completed | University of Missouri-Columbia | 118 | 2020-06-01 | 2025-11-12 |
| Establishing the Safety and Efficacy of Reloxaliase in Patients With Enteric Hyperoxaluria Reloxaliase, Placebo - Enteric Hyperoxaluria | Phase 3 | Terminated | Allena Pharmaceuticals | 92 | 2019-08-26 | 2022-06-10 |
| Evaluate ALLN-177 in Patients With Enteric Hyperoxaluria ALLN-177, Placebo - Enteric Hyperoxaluria | Phase 3 | Completed | Allena Pharmaceuticals | 115 | 2018-05-21 | 2020-02-27 |
| Efficacy of Liposomal Bupivacaine for Pain Control After Percutaneous Nephrostolithotomy liposomal bupivicaine, Bupivacaine, Saline Solution - Renal Calculi, Postoperative Pain | Phase 3 | Withdrawn | Northwell Health | 2017-08-08 | 2017-08-28 | |
| Hydrochlorothiazide for Kidney Stone Recurrence Prevention Placebo oral capsule, 12.5 mg hydrochlorothiazide, 25.0 mg hydrochlorothiazide - Nephrolithiasis | Phase 3 | Completed | Insel Gruppe AG, University Hospital Bern | 416 | 2017-03-09 | 2024-02-01 |
| Trial of Randomized Antibiotic Administration in Percutaneous Nephrolithotomy cephalosporins, Fluoroquinolones, Clindamycin - Kidney Stones | Phase 3 | Completed | Northwell Health | 98 | 2014-09-01 | 2023-09-06 |
| Effectiveness of Silodosin in Medical Expulsive Therapy for Ureteral Pelvic Stone From 4 to 10 mm. Silodosin - Kidney Stone, Expulsive Medical Therapy | Phase 3 | Terminated | Centre Hospitalier Departemental Vendee | 8 | 2014-07-01 | 2016-02-11 |
| Differential Effect of Silodosin Versus Tamsulosin on Stone Clearance After Extra-corporeal Shock Wave Lithotripsy silodosin, Extra-corporeal shock wave lithotripsy, Tamsulosin - Kidney Stones | Phase 3 | Withdrawn | Albert Einstein Healthcare Network | 2012-03-01 | 2017-02-17 | |
| Extracorporeal Shock Wave Lithotriptor Indicated for Fragmenting Urinary Stones in the Kidney LithoSpace Extracorporeal Shockwave Lithotripter - Kidney Stones | Phase 3 | Unknown | Advance Shockwave Technology GmbH | 20 | 2010-06-01 | 2011-06-01 |
| Renalof in the Dissolution of Renal Calculi in Patients With Recurrent Calcic Lithiasis Renalof, Placebo - Recurrent Calcic Urolithiasis | Phase 3 | Completed | Catalysis SL | 110 | 2009-11-01 | 2010-02-04 |
| Visceral Pain From the Upper Urinary Tract - a Trial on the Effect of Morphine and Oxycodone in Patients Undergoing PCNL oxycodone, morphine - Kidney Stones | Phase 3 | Completed | Katja venborg Pedersen | 55 | 2008-12-01 | 2012-07-09 |
| Alfuzosin for Medical Expulsion Therapy of Ureteral Stones Alfuzosin, nifedipine, doxazosin - Kidney Stones | Phase 3 | Unknown | United States Naval Medical Center, San Diego | 240 | 2008-01-01 | 2012-04-27 |
| Pharmacological Modulation of the Intrarenal Pressure During Endourological Procedures in the Upper Urinary Tract Isoproterenol - Kidney Stone, Unexplained Haematuria | Phase 2 / Phase 3 | Completed | Fredericia Hosptial | 12 | 2007-02-01 | 2007-11-16 |
| Effects of the Use of Adjuvant Drugs After Extracorporeal Shockwave Lithotripsy (ESWL) in Renal Calculus Tamsulosin - Renal Calculi | Phase 3 | Unknown | University of Sao Paulo General Hospital | 136 | 2006-08-01 | 2010-10-06 |
| Alfuzosin Hydrochloride to Promote Passage of Distal Ureteral Calculi Alfuzosin Hydrochloride - Kidney Calculi, Ureteral Calculi | Phase 3 | Completed | University of Minnesota | 76 | 2005-09-01 | 2013-03-18 |
| Phase III Randomized, Double-Blind Study of Potassium Phosphate Vs Potassium Citrate for Absorptive Hypercalciuria potassium citrate, potassium phosphate - Hypercalciuria, Kidney Calculi | Phase 3 | Completed | National Center for Research Resources (NCRR) | 300 | 1995-04-01 | 2005-06-24 |
Nephrolithiasis (3) · Hyperoxaluria (2) · Pain, Postoperative (2) · Behavior, Addictive (1) · Colic (1) · Hypercalciuria (1) · Kidney Diseases (1) · Rare Diseases (1) · Ureteral Calculi (1) · Urogenital Diseases (1) · Visceral Pain (1)
Calculi (20) · Female Urogenital Diseases (20) · Female Urogenital Diseases and Pregnancy Complications (20) · Male Urogenital Diseases (20) · Pathological Conditions, Anatomical (20) · Pathological Conditions, Signs and Symptoms (20) · Urinary Calculi (20) · Urolithiasis (20) · Urologic Diseases (20) · Kidney Diseases (19) · Urogenital Diseases (19) · Nephrolithiasis (17) · Signs and Symptoms (4) · Neurologic Manifestations (3) · Pain (3)
Tamsulosin (2) · alfuzosin (2) · oxalate decarboxylase (2) · reloxaliase (2) · silodosin (2) · Ampicillin (1) · Bupivacaine (1) · Cefazolin (1) · Cephalosporins (1) · Ciprofloxacin (1) · Clindamycin (1) · Doxazosin (1) · Fluoroquinolones (1) · Furosemide (1) · Gentamicins (1)
Allena Pharmaceuticals (2) · Insel Gruppe AG, University Hospital Bern (2) · Northwell Health (2) · Advance Shockwave Technology GmbH (1) · Ain Shams University (1) · Albert Einstein Healthcare Network (1) · Catalysis SL (1) · Centre Hospitalier Departemental Vendee (1) · Fredericia Hosptial (1) · Hospital Regional de Alta Especialidad del Bajio (1) · Katja venborg Pedersen (1) · National Center for Research Resources (NCRR) (1) · United States Naval Medical Center, San Diego (1) · University Hospital, Tours (1) · University of Minnesota (1)
United States (9) · France (5) · Germany (3) · Italy (3) · Switzerland (3) · Brazil (2) · Canada (2) · Denmark (2) · Mexico (2) · Spain (2) · United Kingdom (2) · Austria (1) · Belgium (1) · Croatia (1) · Cuba (1)
Annamaria Kausz, MD MS (1) · Brian K. Auge, M.D. (1) · Charles Y. C. Pak (1) · Daniel Fuster (1) · Daniel Fuster, Prof MD (1) · David Clark, MD (1) · David M Hoenig, md (1) · Katie Murray, DO (1) · Manoj Monga, MD (1) · Miguel Srougi, MD (1) · Palle JS Osther, PhD, MD (1) · Palle Osther, Professor (1)
PMID 10360498, PMID 24707884, PMID 27758119, PMID 28608192, PMID 29649900, PMID 30526528, PMID 30961854, PMID 31177306, PMID 31588790, PMID 36856614, PMID 37578113, PMID 38319254, PMID 38965611, PMID 39028573, PMID 40210001
2016 (1), 2018 (1)