35 completed, 7 unknown, 3 terminated, 2 active not recruiting. 50 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 50 | Completed 35, Unknown 7, Terminated 3, Active not recruiting 2, Enrolling by invitation 2, Withdrawn 1 |
Follow Keratosis: new trials by email Literature Review of Keratosis trials Research Report on Keratosis
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Evaluating Whether Intact Fish Skin Graft Can Decrease the Need for Autograft in the Treatment of Deep Partial-Thickness Burns Intact fish skin graft, autograft - Partial-thickness Burn Wounds | Phase 4 | Enrolling by invitation | Kerecis Ltd. | 65 | 2026-06-01 | 2026-11-12 |
| Combination Therapy of 5-Fluorouracil and CALcipotriol Versus 5-Fluorouracil in the Treatment of Actinic Keratosis 5FU-Calcipotriol, 5-FU 50 MG/ML Topical Cream - Actinic Keratoses | Phase 4 | Completed | Maastricht University Medical Center | 232 | 2024-09-04 | 2026-10-29 |
| Efficacy and Safety of Cryotherapy Versus 5-Fluorouracil in the Treatment of Actinic Keratosis Cryotherapy, 5Fluorouracil - Actinic Keratoses | Phase 4 | Enrolling by invitation | University of California, Davis | 73 | 2024-07-01 | 2026-07-06 |
| Trial Assessing the Impact on Facial Skin Quality, Hydration, and Skin Barrier of Three (3) Hydrafacial Treatments in Adults of All Skin Types. HydraFacial Syndeo System, ReGen-GF, HydraFacial Elite MD System - Cutis Laxa Facialis, Xeroderma | Phase 4 | Completed | Austin Institute for Clinical Research | 27 | 2023-11-20 | 2024-10-24 |
| Tirbanibulin 1% Ointment for the Treatment of Actinic Keratosis on the Back of the Hands Tirbanibulin - Actinic Keratoses | Phase 4 | Withdrawn | Medical University of Graz | 2023-10-01 | 2024-05-30 | |
| Tirbanibulin 1% Ointment for the Treatment of Chronically Sun-damaged Skin on the Face Tirbanibulin - Actinic Keratosis | Phase 4 | Completed | Medical University of Graz | 22 | 2023-05-11 | 2023-11-14 |
| Cryotherapy in Combination With Red Light PDT for Actinic Keratosis of Full Face Ameluz 10% Topical Gel, Red Light PDT, Cryotherapy - Actinic Keratoses | Phase 4 | Active not recruiting | Psoriasis Treatment Center of Central New Jersey | 40 | 2023-05-03 | 2026-10-14 |
| A Study of Tirbanibulin on the Wellbeing of Participants With Actinic Keratoses Tirbanibulin 2.5 mg ointment - Actinic Keratosis | Phase 4 | Completed | Almirall, S.A. | 334 | 2023-01-20 | 2025-02-20 |
| A Study of Tirbanibulin Ointment and Diclofenac Sodium Gel for the Treatment of Adult Participants With Actinic Keratosis on the Face or Scalp Tirbanibulin (Klisyri®) 10 mg/g ointment, Diclofenac Sodium 3% Gel - Keratosis, Actinic | Phase 4 | Active not recruiting | Almirall, S.A. | 447 | 2022-10-24 | 2025-02-11 |
| Earliest Stage Treatment of Aktinic Keratosis With Imiquimod 3.75% Cream Imiquimod 3.75% Cream - Actinic Keratoses | Phase 4 | Completed | Medical University of Graz | 48 | 2021-04-16 | 2022-01-11 |
| Scientific Substantiation and Assessment of the Effectiveness of Pathogenetic Methods of Therapy for Congenital Ichthyosis in Children Secukinumab Injection, Ustekinumab Injection, Dupilumab Injection - Congenital Ichthyosis | Phase 4 | Unknown | National Medical Research Center for Children's Health, Russian Federation | 50 | 2021-03-01 | 2021-08-09 |
| Frequency and Intensity of Local Reactions in Patients Treated With 4% 5-FU vs 4% 5-FU Associated With an Emollient Cream: a Randomised, Controlled Clinical Trial 5-fluorouracil 4% (Tolak), Dexeryl - Actinic Keratoses | Phase 4 | Completed | Pierre Fabre Medicament | 146 | 2021-02-16 | 2022-09-19 |
| Duration of Ameluz Application in Acral Actinic Keratoses Response Ameluz - Actinic Keratoses, Photodamaged Skin | Phase 4 | Terminated | Royal Cornwall Hospitals Trust | 28 | 2019-10-30 | 2024-07-26 |
| Menthol for PDT Pain Relief Menthol, Aqueous Cream - Actinic Keratosis | Phase 4 | Completed | University of Dundee | 10 | 2018-10-23 | 2021-03-09 |
| Aminolevulinic Acid-photodynamic Therapy for Facial Actinic Keratosis Treatment and Prevention ALA - Actinic Keratoses | Phase 4 | Unknown | Shanghai Dermatology Hospital | 300 | 2018-08-30 | 2019-03-19 |
| An A Study Assessing Subject Satisfaction With A-101 Topical Solution for Seborrheic Keratoses A-101 Topical Solution - Seborrheic Keratosis | Phase 4 | Completed | Aclaris Therapeutics, Inc. | 41 | 2018-03-21 | 2019-10-02 |
| Evaluating Skin Appearance Following 5-Flourouracil Cream for Treatment of Actinic Keratosis and the Effects of Topical Agents Topical Steroid Ointment, Vaseline, Skin Barrier Moisturier - Actinic Keratoses | Phase 4 | Completed | University of Arizona | 30 | 2017-10-10 | 2019-06-25 |
| PRO With Luxerm® in the Field Treatment of Thin and Non-hyperkeratotic Non-pigmented AK Methyl Aminolaevulinate 16% Cream - Actinic Keratoses | Phase 4 | Completed | Galderma R&D | 50 | 2017-06-07 | 2021-02-18 |
| Photodynamic Therapy of Actinic Keratosis of the Face and Scalp With and Without Prior Curettage No curettage, Curettage - Keratosis, Actinic | Phase 4 | Completed | Bispebjerg Hospital | 25 | 2017-06-01 | 2018-10-09 |
| Efficacy of Ingenol Mebutate on Actinic Keratoses and Field Cancerization vs Cryotherapy Ingenol mebutate, cryotherapy - Actinic Keratosis | Phase 4 | Completed | University of Campania Luigi Vanvitelli | 50 | 2017-04-12 | 2019-09-24 |
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Keratosis, Actinic (46) · Ichthyosis Vulgaris (2) · Burns (1) · Ichthyosis (1) · Keratosis, Seborrheic (1) · Netherton Syndrome (1) · Photosensitivity Disorders (1)
Skin Diseases (50) · Skin and Connective Tissue Diseases (50) · Neoplasms (46) · Precancerous Conditions (46) · Congenital Abnormalities (3) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (3) · Skin Abnormalities (3) · Genetic Diseases, Inborn (2) · Ichthyosis (2) · Infant, Newborn, Diseases (2) · Skin Diseases, Genetic (2) · Abnormalities, Multiple (1) · Ichthyosiform Erythroderma, Congenital (1) · Wounds and Injuries (1)
Imiquimod (11) · Aminolevulinic Acid (8) · 3-ingenyl angelate (6) · Diclofenac (6) · Cryotherapy (5) · Fluorouracil (5) · tirbanibulin (4) · Photochemotherapy (3) · methyl 5-aminolevulinate (3) · Cryosurgery (2) · Gels (2) · Ointments (2) · BF-200 ALA (1) · Bacitracin (1) · Biafine (1)
Medical University of Graz (3) · Almirall, S.A. (2) · Galderma R&D (2) · Graceway Pharmaceuticals, LLC (2) · LEO Pharma (2) · MEDA Pharma GmbH & Co. KG (2) · Maastricht University Medical Center (2) · University Hospital Regensburg (2) · Wake Forest University (2) · Aclaris Therapeutics, Inc. (1) · Austin Institute for Clinical Research (1) · Bispebjerg Hospital (1) · Derm Research @ 888 Inc. (1) · Dermatology, Laser & Vein Specialists of the Carolinas (1) · Dong-A University (1)
United States (20) · Germany (10) · Austria (5) · Italy (5) · United Kingdom (5) · France (4) · Spain (4) · Netherlands (2) · South Korea (2) · Canada (1) · China (1) · Denmark (1) · Finland (1) · Poland (1) · Russia (1)
Steve Feldman, MD, PhD (2) · Alberto Lecchi (1) · Alexandra Geusau, Prof. Dr. (1) · Carlos Serra (1) · Christopher B Zachary, MBBS. FRC[ (1) · Claus Garbe, MD (1) · Daniel Eisen, MD (1) · Darrell S Rigel, MD (1) · David Gordon, MD (1) · Dr. Giuseppe Argenziano,, MD, PhD (1) · Edward Lain, MD, MBA (1) · Eggert Stockfleth, Prof.Dr.med. (1) · Gary Goldenberg, MD (1) · Gary S Goldenberg, MD (1)
PMID 10607349, PMID 11966728, PMID 12533168, PMID 15097955, PMID 15168956, PMID 17822489, PMID 18067627, PMID 18955209, PMID 19221274, PMID 19467365, PMID 20231500, PMID 20514316, PMID 20725550, PMID 20729935, PMID 21753882, PMID 22055282, PMID 22329784, PMID 22417254, PMID 22714759, PMID 23510990, PMID 23553119, PMID 24037822, PMID 24589500, PMID 24672213, PMID 24818175, PMID 24892649, PMID 25174261, PMID 25950503, PMID 26300464, PMID 26921093, PMID 27167413, PMID 27672408, PMID 28532759, PMID 28979661, PMID 29030864, PMID 29070025, PMID 30329163, PMID 30855743, PMID 31334125, PMID 31407414, PMID 31961446, PMID 33476658, PMID 35475852, PMID 7947197, PMID 8918873, PMID 9092763, PMID 9627707
2014 (1), 2015 (1)