5 completed, 2 terminated, 2 unknown, 1 active not recruiting. 5 Phase 2, 3 Phase 1, 1 Not applicable, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 5 | Terminated 2, Active not recruiting 1, Completed 1, Enrolling by invitation 1 |
| Phase 1 | 3 | Completed 2, Enrolling by invitation 1 |
| Not applicable | 1 | Unknown 1 |
| Phase 3 | 1 | Completed 1 |
Follow Job Syndrome: new trials by email Literature Review of Job Syndrome trials Research Report on Job Syndrome
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Study of Efficacy and Safety of the Plasmapheresis Method With Albumin Compensation Compared With the Plasmapheresis Method Without Albumin Compensation for Aging Biomarkers Correction in Men and Women Aged 40 to 55 Years Old plasma exchange with albumin, plasma exchange without albumin - Hypercholesterolemia, Hyperbilirubinemia | Not applicable | Unknown | National Medical Research Center for Rehabilitation and Balneology | 80 | 2021-05-12 | 2021-05-21 |
| Safety, Tolerability, and Immunogenicity of One Dose of NDV 3A Vaccine in People With STAT3-Mutated Hyper-IgE Syndrome NDV-3A - Autosomal-dominant Hyper-IgE Syndrome | Phase 2 | Terminated | National Institute of Allergy and Infectious Diseases (NIAID) | 3 | 2016-11-17 | 2020-06-30 |
| CAMB/MAT2203 in Patients With Mucocutaneous Candidiasis Amphotericin B - Candidiasis, Chronic Mucocutaneous | Phase 2 | Completed | Matinas BioPharma Nanotechnologies, Inc. | 4 | 2016-09-27 | 2024-08-07 |
| NFIL3-induced Pathological Enhancement of IgE Class Switch Recombination in Hyper-IgE Syndrome Job Syndrome | Unknown | Shanghai Children's Medical Center | 40 | 2014-09-01 | 2014-08-29 | |
| Sequential Cadaveric Lung and Bone Marrow Transplant for Immune Deficiency Diseases CD3/CD19 negative allogeneic hematopoietic stem cells - Severe Combined Immunodeficiency (SCID), Immunodeficiency With Predominant T-cell Defect, Unspecified | Phase 1 / Phase 2 | Enrolling by invitation | Paul Szabolcs | 16 | 2013-06-20 | 2025-12-15 |
| Pilot Study of Reduced-Intensity Hematopoietic Stem Cell Transplant of DOCK8 Deficiency Reduced-intensity hematopoietic stem cell, Fludarabine(Fludara, Berlex Laboratories), Cyclophosphamide(CTX, Cytoxan) - DOCK8 Deficiency | Phase 2 | Active not recruiting | National Cancer Institute (NCI) | 70 | 2010-10-05 | 2026-10-16 |
| Effect of Ranitidine on Hyper-IgE Recurrent Infection (Job's) Syndrome Ranitidine, Placebo - JOB's Syndrome, Hyper-IgE Recurrent Infection Syndrome | Phase 2 | Terminated | National Institute of Allergy and Infectious Diseases (NIAID) | 16 | 2007-09-01 | 2013-02-04 |
| Omalizumab to Treat Hyper-IgE (Job's) Syndrome Omalizumab (Xolair) - Hyper-IgE Syndrome, Job's Syndrome | Phase 1 | Completed | National Institute of Allergy and Infectious Diseases (NIAID) | 1 | 2005-11-24 | 2017-07-02 |
| Posaconazole to Treat Invasive Fungal Infections Posaconazole - Granulomatous Disease, Chronic, Job's Syndrome | Phase 3 | Completed | National Institute of Allergy and Infectious Diseases (NIAID) | 50 | 2002-04-11 | 2017-07-02 |
| Natural History, Management, and Genetics of the Hyperimmunoglobulin E Recurrent Infection Syndrome (HIES) Infections, Pneumonia | Recruiting | National Institute of Allergy and Infectious Diseases (NIAID) | 600 | 2000-08-10 | 2026-09-28 | |
| Learning and Behavior Problems in Children With Chronic Granulomatous Disease and Related Disorders Chediak Higashi Syndrome, Chronic Granulomatous Disease | Completed | National Institute of Allergy and Infectious Diseases (NIAID) | 150 | 2000-06-01 | 2008-03-04 | |
| Diagnostic Effectiveness of Virtual Bronchoscopy virtual bronchoscopy - Bronchogenic Carcinoma, Chronic Granulomatous Disease | Phase 1 | Completed | National Institutes of Health Clinical Center (CC) | 120 | 1995-12-01 | 2008-03-04 |
Granulomatous Disease, Chronic (4) · Immunologic Deficiency Syndromes (4) · Infections (2) · Candidiasis, Chronic Mucocutaneous (1) · Carcinoma, Bronchogenic (1) · Cardiovascular Diseases (1) · Chediak-Higashi Syndrome (1) · Chronic Disease (1) · Common Variable Immunodeficiency (1) · Dermatitis (1) · Diabetes Mellitus (1) · Gout (1) · Granulomatosis with Polyangiitis (1) · Hyperbilirubinemia (1)
Congenital, Hereditary, and Neonatal Diseases and Abnormalities (12) · Genetic Diseases, Inborn (12) · Hematologic Diseases (12) · Hemic and Lymphatic Diseases (12) · Phagocyte Bactericidal Dysfunction (12) · Primary Immunodeficiency Diseases (12) · Immune System Diseases (11) · Leukocyte Disorders (11) · Immunologic Deficiency Syndromes (8) · Pathologic Processes (6) · Pathological Conditions, Signs and Symptoms (6) · Disease Attributes (5) · Bacterial Infections and Mycoses (4) · Chronic Disease (4) · Genetic Diseases, X-Linked (4)
Albumins (1) · Amphotericin B (1) · Busulfan (1) · Cyclophosphamide (1) · Omalizumab (1) · Plasma Exchange (1) · Plasmapheresis (1) · Ranitidine (1) · Whole-Body Irradiation (1) · posaconazole (1)
National Institute of Allergy and Infectious Diseases (NIAID) (6) · Matinas BioPharma Nanotechnologies, Inc. (1) · National Cancer Institute (NCI) (1) · National Institutes of Health Clinical Center (CC) (1) · National Medical Research Center for Rehabilitation and Balneology (1) · Paul Szabolcs (1) · Shanghai Children's Medical Center (1)
United States (10) · Russia (1)
Alexandra F Freeman, M.D. (1) · Alexandra Freeman, M.D. (1) · Alexandra Freeman, MD (1) · Corina E Gonzalez, M.D. (1) · Ilmira Gilmutdinova (1) · Paul Szabolcs, MD (1)