2 completed, 1 active not recruiting, 1 recruiting. 2 Phase 2, 1 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 2 | Active not recruiting 1, Completed 1 |
| Phase 1 | 1 | Recruiting 1 |
Follow IPEX: new trials by email Literature Review of IPEX trials Research Report on IPEX
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| CD4^LVFOXP3 in Participants With IPEX CD4^LVFOXP3 - IPEX | Phase 1 | Recruiting | Bacchetta, Rosa, MD | 30 | 2022-03-22 | 2025-05-22 |
| Conception of a Diagnosis, Prognosis and Therapeutic Decision Tool for Patients With Autoimmunity and Inflammation Collection of samples - Autoimmune Lymphoproliferative Syndrome, Autoimmune Cytopenia | Completed | Institut National de la Santé Et de la Recherche Médicale, France | 325 | 2021-09-07 | 2026-09-18 | |
| Reduced Intensity Conditioning for Hemophagocytic Syndromes or Selected Primary Immune Deficiencies (BMT CTN 1204) Hematopoietic Stem Cell Transplant - Hemophagocytic Lymphohistiocytosis, Chronic Active Epstein-Barr Virus Infection | Phase 2 | Completed | Medical College of Wisconsin | 47 | 2013-12-01 | 2022-12-08 |
| Immune Disorder HSCT Protocol Transplant preparative regimen of alemtuzumab, fludarabine, thiotepa, and melphalan - Immune Deficiency Disorders, Severe Combined Immunodeficiency | Phase 2 | Active not recruiting | Washington University School of Medicine | 20 | 2013-04-29 | 2026-02-19 |
Lymphohistiocytosis, Hemophagocytic (3) · Autoimmune Diseases (2) · Autoimmune Lymphoproliferative Syndrome (2) · Granulomatous Disease, Chronic (2) · Hyper-IgM Immunodeficiency Syndrome (2) · Arthritis, Juvenile (1) · Autoimmune enteropathy (1) · Bruton type agammaglobulinemia (1) · Chediak-Higashi Syndrome (1) · Common Variable Immunodeficiency (1) · DiGeorge Syndrome (1) · Diabetes Mellitus, Type 1 (1) · Hepatitis, Autoimmune (1) · Immune System Diseases (1) · Immunologic Deficiency Syndromes (1)
Congenital, Hereditary, and Neonatal Diseases and Abnormalities (3) · Genetic Diseases, Inborn (3) · Hematologic Diseases (3) · Hemic and Lymphatic Diseases (3) · Histiocytosis (3) · Histiocytosis, Non-Langerhans-Cell (3) · Immune System Diseases (3) · Lymphatic Diseases (3) · Pathologic Processes (3) · Pathological Conditions, Signs and Symptoms (3) · Blood Coagulation Disorders (2) · Blood Protein Disorders (2) · Chronic Disease (2) · Cytopenia (2) · Disease Attributes (2)
Melphalan (1) · Stem Cell Transplantation (1) · Thiotepa (1) · fludarabine (1)
Bacchetta, Rosa, MD (1) · Institut National de la Santé Et de la Recherche Médicale, France (1) · Medical College of Wisconsin (1) · Washington University School of Medicine (1)
United States (3) · Canada (1) · France (1)
Jessie Alexander, MD (1) · Mary Horowitz, MD, MS (1)
PMID 31599480, PMID 37042921, PMID 42023429
U10HL069294 (1), U24CA076518 (1)