4 recruiting. 4 Phase 2, 3 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 4 | Recruiting 4 |
| Phase 1 | 3 | Recruiting 3 |
Follow Intestinal Polyposis: new trials by email Literature Review of Intestinal Polyposis trials Research Report on Intestinal Polyposis
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| An Investigational Drug (TPST-1495) in Patients With Familial Adenomatous Polyposis Biopsy Procedure, Biospecimen Collection, EP2/EP4 Antagonist TPST-1495 - Colorectal Carcinoma, Familial Adenomatous Polyposis | Phase 2 | Recruiting | National Cancer Institute (NCI) | 38 | 2026-03-31 | 2026-09-14 |
| Safety and Efficacy of Tegavivint in Patients With Metastatic Colorectal Carcinoma Tegavivint - Metastatic Colorectal Carcinoma (mCRC), Colorectal Cancer (CRC) | Phase 1 / Phase 2 | Recruiting | HonorHealth Research Institute | 126 | 2026-02-17 | 2026-03-11 |
| Evaluate REC-4881 in Participants With Familial Adenomatous Polyposis (FAP) REC-4881, Placebo - Familial Adenomatous Polyposis | Phase 1 / Phase 2 | Recruiting | Recursion Pharmaceuticals Inc. | 67 | 2023-07-10 | 2026-06-05 |
| FOG-001 in Locally Advanced or Metastatic Solid Tumors FOG-001, mFOLFOX-6, Nivolumab - Cancer, Colorectal Cancer | Phase 1 / Phase 2 | Recruiting | Parabilis Medicines, Inc. | 619 | 2023-05-23 | 2026-10-07 |
Adenomatous Polyposis Coli (4) · Colorectal Neoplasms (3) · Carcinoma, Hepatocellular (1) · Craniopharyngioma (1) · Desmoid Tumors (1) · Endometrial Neoplasms (1) · Neoplasm Metastasis (1) · Neoplasms (1) · Prostatic Neoplasms (1)
Adenoma (4) · Adenomatous Polyps (4) · Colonic Diseases (4) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (4) · Digestive System Diseases (4) · Digestive System Neoplasms (4) · Gastrointestinal Diseases (4) · Gastrointestinal Neoplasms (4) · Genetic Diseases, Inborn (4) · Intestinal Diseases (4) · Intestinal Neoplasms (4) · Neoplasms by Histologic Type (4) · Neoplasms by Site (4) · Neoplasms, Glandular and Epithelial (4)
Bevacizumab (1) · Biopsy (1) · Endoscopy, Digestive System (1) · Endoscopy, Gastrointestinal (1) · Fluorouracil (1) · Gastroscopy (1) · Leucovorin (1) · Nivolumab (1) · Oxaliplatin (1) · Specimen Handling (1) · trifluridine tipiracil drug combination (1)
HonorHealth Research Institute (1) · National Cancer Institute (NCI) (1) · Parabilis Medicines, Inc. (1) · Recursion Pharmaceuticals Inc. (1)
United States (4) · Australia (1)
Benjamin Oshrine (1) · Niloy J Samadder (1)
P30CA014520 (1), UG1CA242596 (1), UG1CA242635 (1)