115 completed, 75 unknown, 68 recruiting, 17 not yet recruiting. 92 Not applicable, 53 Phase 2, 24 Phase 3, 16 Phase 4, 12 Phase 1.
Follow Interstitial Lung Disease: new trials by email Literature Review of Interstitial Lung Disease trials Research Report on Interstitial Lung Disease
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Chronic COUGH Management in Interstitial Lung DisEase Non-pharmacological cough control therapy, Healthy lifestyle - Interstitial Lung Disease, Chronic Cough | Not applicable | Not yet recruiting | Aveiro University | 60 | 2027-12-20 | 2025-01-20 |
| A Study to Assess the Efficacy and Safety of Treprostinil Palmitil Inhalation Powder (TPIP) in Participants With Progressive Pulmonary Fibrosis (PPF) Treprostinil Palmitil Inhalation Powder, Placebo - Progressive Pulmonary Fibrosis, Interstitial Lung Disease | Phase 3 | Not yet recruiting | Insmed Incorporated | 800 | 2026-12-01 | 2026-09-04 |
| Hyperpolarized Xenon MRI in Adults With Pulmonary Hypertension in Interstitial Lung Disease and Systemic Sclerosis Hyperpolarized 129 Xenon Gas - Interstitial Lung Disease, Pulmonary Hypertension | Phase 2 | Not yet recruiting | Bastiaan Driehuys | 51 | 2026-11-01 | 2026-09-15 |
| Immunomodulatory Treatment of Interstitial Lung Disease Associated With Surfactant Related Gene Variants Azithromycin 250 mg x3/week (3 tablets/week), Prednisone 10 mg/day, Hydroxychloroquine 400 mg/day - Interstitial Lung Disease | Phase 2 | Not yet recruiting | Assistance Publique - Hôpitaux de Paris | 30 | 2026-11-01 | 2026-09-22 |
| Study Evaluating 68GA-FAPI-46 PET/CT in Patients With Interstitial Lung Disease ⁶⁸Ga-FAPI-46, PET/CT - Interstitial Lung Disease | Phase 1 | Not yet recruiting | Mayo Clinic | 10 | 2026-10-16 | 2026-09-18 |
| Gabapentin vs. Benzonatate vs. Standard of Care for Cough in ILD Gabapentin, Benzonatate 200 mg, Standard of care treatment for ILD - Interstitial Lung Disease | Phase 4 | Not yet recruiting | Post Graduate Institute of Medical Education and Research, Chandigarh | 177 | 2026-10-07 | 2026-10-08 |
| Human Umbilical Cord Mesenchymal Stem Cell Injection for the Treatment of Interstitial Lung Disease Human umbilical cord mesenchymal stem cell injection - Interstitial Lung Disease | Phase 1 | Not yet recruiting | Shanghai Life Science & Technology | 24 | 2026-10-01 | 2026-05-11 |
| Fibrotic Disease Activity in Cardiopulmonary Disorders Using 18F-Fibroblast Activation Protein Inhibitor (18F-FAPI-74) PET/CT Imaging [18F]FAPI-74, 18F-FAPI-74 PET/CT Imaging - Allogeneic Stem Cell Transplantation, Lung Allograft Transplantation | Phase 3 | Recruiting | National Heart, Lung, and Blood Institute (NHLBI) | 210 | 2026-09-18 | 2026-10-06 |
| Titrated Ambulatory Oxygen in Fibrotic ILD and COPD With Isolated Exertional Hypoxemia Portable Oxygen Concentrator, Portable compressed oxygen D-tanks, No ambulatory oxygen therapy - Interstitial Lung Disease, Chronic Obstructive Pulmonary Disease | Not applicable | Enrolling by invitation | State University of New York at Buffalo | 24 | 2026-09-02 | 2026-09-09 |
| Risk Factors of Venous Thrombotic Event in Interstitial Lung Disease Interstitial Lung Disease, Venous Thromboembolism | Not yet recruiting | Sohag University | 100 | 2026-09-01 | 2026-09-22 | |
| A Phase 3 Trial of Inhaled Mosliciguat in PH-ILD (PHrontier) Mosliciguat, Placebo, Dry Powder Inhaler - Pulmonary Hypertension, Interstitial Lung Disease | Phase 3 | Recruiting | Pulmovant, Inc. | 376 | 2026-08-31 | 2026-09-11 |
| Virtual Nurse and Social Worker Palliative Care Team to Improve Quality of Life in Veterans With Heart Failure or COPD Virtual Nurse and Social Worker Palliative Care Team, Enhanced Implementation Support, Standard Implementation Support - Heart Failure, Pulmonary Disease, Chronic Obstructive | Not applicable | Enrolling by invitation | VA Office of Research and Development | 420 | 2026-08-06 | 2026-08-24 |
| Predictors of Pulmonary Embolism in Interstitial Lung Disease With Worsening Symptoms Pulmonary Embolism, Interstitial Lung Disease | Not yet recruiting | Assiut University | 70 | 2026-08-01 | 2026-07-27 | |
| Emapalumab MDA5 Rapidly Progressive Interstitial Lung Disease (RP-ILD) Study Emapalumab - Dermatomyositis, Dermatomyositis Sine Myositis | Phase 2 | Recruiting | University of Miami | 5 | 2026-07-23 | 2026-08-25 |
| An Open-Label Extension Study of Treprostinil Palmitil Inhalation Powder (TPIP) in Participants With Pulmonary Hypertension Associated With Interstitial Lung Disease (PH-ILD) Treprostinil Palmitil Inhalation Powder, Placebo - Pulmonary Hypertension, Interstitial Lung Disease | Phase 3 | Recruiting | Insmed Incorporated | 344 | 2026-07-20 | 2026-08-13 |
| The Benefits of Home Exercise in Pulmonary Hypertension Interstitial Lung Disease Home Exercise Program, Aerobic Plus Strength Training, Home Exercise Program, Aerobic Only - Pulmonary Hypertension, Interstitial Lung Disease | Not applicable | Recruiting | University of Rochester | 30 | 2026-07-15 | 2026-07-24 |
| Advanced Imaging to Assess the Effect of Immunosuppression on Progressive Fibrosis [68Ga]CBP8, Gadoterate Meglumine - Interstitial Lung Disease, Pulmonary Fibrosis | Phase 2 | Recruiting | Peter Caravan | 15 | 2026-05-14 | 2026-07-14 |
| Clinical Efficacy of Telitacicept in Sjögren's Disease With Interstitial Lung Disease Telitacicept 160mg, Conventional treatment - Sjögren's Disease, Interstitial Lung Disease | Recruiting | Peking University People's Hospital | 60 | 2026-05-01 | 2026-09-28 | |
| Effects of Oxygen Supplementation During the 6-Minute Walk Test in Chronic Respiratory Failure or Exertional Hypoxemia Usual Oxygen During 6-Minute Walk Test, Supplemental Oxygen During 6-Minute Walk Test - Chronic Respiratory Failure, Hypoxemia | Not applicable | Recruiting | Istituti Clinici Scientifici Maugeri SpA | 114 | 2026-04-02 | 2026-06-23 |
| Clinical Study on the Application of PET Probes Targeting DDR2 in the Diagnosis of Interstitial Lung Disease With Cognitive Impairment Interstitial Lung Disease | Not yet recruiting | Daping Hospital and the Research Institute of Surgery of the Third Military Medical University | 50 | 2026-04-01 | 2026-03-11 |
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Lung Diseases, Interstitial (315) · Pulmonary Disease, Chronic Obstructive (51) · Idiopathic Pulmonary Fibrosis (49) · Pulmonary Fibrosis (42) · Hypertension, Pulmonary (34) · Scleroderma, Systemic (20) · Arthritis, Rheumatoid (17) · Asthma (15) · Connective Tissue Diseases (15) · Dyspnea (15) · Lung Diseases (15) · Sarcoidosis (14) · Scleroderma, Diffuse (14) · Lung Neoplasms (13) · Motor Activity (13)
Respiratory Tract Diseases (314) · Lung Diseases (300) · Pathological Conditions, Signs and Symptoms (111) · Pathologic Processes (101) · Skin and Connective Tissue Diseases (61) · Immune System Diseases (59) · Chronic Disease (52) · Disease Attributes (52) · Lung Diseases, Obstructive (52) · Cardiovascular Diseases (45) · Connective Tissue Diseases (42) · Vascular Diseases (40) · Fibrosis (39) · Pulmonary Fibrosis (38) · Hypersensitivity (35)
treprostinil (10) · Blood Specimen Collection (7) · Cyclophosphamide (6) · Mycophenolic Acid (6) · pirfenidone (6) · Exercise (5) · Oxygen (4) · Respiratory Function Tests (4) · Rituximab (4) · Abatacept (3) · Adrenal Cortex Hormones (3) · Hydroxychloroquine (3) · Spirometry (3) · Walk Test (3) · nintedanib (3)
Assiut University (11) · United Therapeutics (8) · Assistance Publique - Hôpitaux de Paris (5) · Mayo Clinic (5) · Bastiaan Driehuys (4) · Columbia University (4) · Duke University (4) · Fondazione Policlinico Universitario Agostino Gemelli IRCCS (4) · Insmed Incorporated (4) · Laval University (4) · Royal Brompton & Harefield NHS Foundation Trust (4) · University of Zurich (4) · Weill Medical College of Cornell University (4) · Aveiro University (3) · Central Hospital, Nancy, France (3)
United States (101) · United Kingdom (35) · France (32) · Canada (30) · Germany (22) · China (21) · Italy (21) · Australia (14) · Belgium (14) · Spain (13) · Turkey (Türkiye) (13) · Netherlands (10) · Poland (10) · South Korea (10) · Egypt (9)
Aliaa Barakat, PhD (2) · David Bekelman, MD MPH (2) · David Palma, MD (2) · Dennis Jensen, PhD (2) · Juhong Shi, M.D (2) · Konrad E Bloch, MD (2) · Leighton Chan, M.D. (2) · Rajan Saggar, MD (2) · Ronald G Crystal, MD (2) · Yousef Althulth, MD (2) · Alda S Marques, PhD (1)
PMID 35688625, PMID 42776606, PMID 11462065, PMID 12454299, PMID 12917227, PMID 15135701, PMID 15618580, PMID 15653996, PMID 15692967, PMID 15888847, PMID 16415388, PMID 16790698, PMID 16899504, PMID 16984837, PMID 17469162, PMID 17485423, PMID 17684286, PMID 17717203, PMID 17885266, PMID 17901414, PMID 18245143, PMID 18360183, PMID 18641099, PMID 19074597, PMID 19168766, PMID 19363213, PMID 19633538, PMID 19776222, PMID 19809049, PMID 19892673, PMID 20155830, PMID 20221746, PMID 20682528, PMID 20740615, PMID 20843660, PMID 20851923, PMID 20851924, PMID 21325944, PMID 21925058, PMID 22392031, PMID 22584759, PMID 23328889, PMID 23845983, PMID 23905526, PMID 23975232, PMID 23983768, PMID 24332409, PMID 24431095, PMID 24567921, PMID 24692573
2023 (3), 2016 (2), 2025 (2), 2008 (1), 2015 (1), K12TR005295 (1), K23HL086714 (1), R01HL089758 (1), R01HL089901 (1), R01HL098329 (1), R01HL103676 (1), R01HL126771 (1), R01HL137234 (1), R01HL168126 (1), R01HL171240 (1)