7 completed, 1 terminated. 8 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 8 | Completed 7, Terminated 1 |
Follow Insulin Sensitivity: new trials by email Literature Review of Insulin Sensitivity trials Research Report on Insulin Sensitivity
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Topical Insulin for Ocular Surface Interface in Dry Eye Disease Artificial tear, insulin human - Dry Eye, Insulin Sensitivity | Phase 4 | Completed | Khyber Teaching Hospital | 128 | 2025-04-14 | 2026-08-14 |
| Study of HIV-Infected and Uninfected Pregnant Woman/Child Dyads in Gaborone, Botswana Zidovudine, Nevirapine - HIV, Insulin Sensitivity | Phase 4 | Completed | Ann & Robert H Lurie Children's Hospital of Chicago | 495 | 2016-08-22 | 2022-07-20 |
| Acute Effects of an Oral Fat Load on Skeletal Muscle and Hepatic Insulin Sensitivity fat orally - Insulin Sensitivity | Phase 4 | Completed | German Diabetes Center | 20 | 2012-03-01 | 2023-08-25 |
| Insulin Sensitivity and Beta Cell Function After Carbohydrate Loading in Hip Replacement Surgery Experimental: PreOp, NutriciaNordica AB, Placebo Comparator: Water - Insulin Sensitivity | Phase 4 | Completed | Karolinska Institutet | 23 | 2012-01-01 | 2014-06-05 |
| Oral Contraceptives, Insulin Resistance and Cardiovascular Risk Profile in Pre-Menopausal Women Ortho Cyclen® - Insulin Sensitivity, Cardiovascular Risk | Phase 4 | Completed | Virginia Commonwealth University | 47 | 2011-11-01 | 2018-08-08 |
| Combination Metformin and Oral Contraception for Polycystic Ovary Syndrome (PCOS) placebo, metformin - Polycystic Ovary Syndrome, PCOS | Phase 4 | Terminated | Virginia Commonwealth University | 28 | 2005-11-01 | 2014-08-20 |
| Insulin Resistance and Intramyocellular Lipid Content in Glucose Intolerant Subjects Receiving Rosiglitazone Rosiglitazone, Placebo - Insulin Sensitivity | Phase 4 | Completed | University of Texas Southwestern Medical Center | 24 | 2004-02-01 | 2008-09-03 |
| Effects of Rosiglitazone and Metformin on Metabolism in Type 2 Diabetes Rosiglitazone, Metformin, Placebo - Insulin Sensitivity, Type 2 Diabetes | Phase 4 | Completed | Turku University Hospital | 48 | 2000-10-01 | 2015-08-18 |
Insulin Resistance (8) · Diabetes Mellitus (1) · Diabetes Mellitus, Type 2 (1) · Dry Eye Syndromes (1) · Glucose Intolerance (1) · Polycystic Ovary Syndrome (1)
Glucose Metabolism Disorders (8) · Hyperinsulinism (8) · Metabolic Diseases (8) · Nutritional and Metabolic Diseases (8) · Endocrine System Diseases (3) · Adnexal Diseases (1) · Cysts (1) · Diabetes Mellitus (1) · Eye Diseases (1) · Female Urogenital Diseases (1) · Female Urogenital Diseases and Pregnancy Complications (1) · Genital Diseases (1) · Genital Diseases, Female (1) · Gonadal Disorders (1) · Hyperglycemia (1)
Metformin (2) · Rosiglitazone (2) · Insulin (1) · Lubricant Eye Drops (1) · Moxifloxacin (1) · Nevirapine (1) · Zidovudine (1)
Virginia Commonwealth University (2) · Ann & Robert H Lurie Children's Hospital of Chicago (1) · German Diabetes Center (1) · Karolinska Institutet (1) · Khyber Teaching Hospital (1) · Turku University Hospital (1) · University of Texas Southwestern Medical Center (1)
United States (3) · Botswana (1) · Finland (1) · Germany (1) · Pakistan (1) · Sweden (1)
Jennifer Jao, MD, MPH (1) · Kai Cheang, Pharm. D. (1) · Leo Dunn, MD (1) · Lidia S Szczepaniak, PhD (1) · Michael Roden, Prof., MD (1) · Pirjo Nuutila, MD, PhD (1) · Shafiq Tanvee, MBBS, FCPS (1)
PMID 21733508, PMID 24007934, PMID 28112681, PMID 28778047, PMID 30802601, PMID 32434996, PMID 34704121, PMID 36240387
R01DK109881 (1)