14 completed, 6 recruiting, 6 unknown, 2 terminated. 16 Not applicable, 3 Phase 1, 3 Phase 2, 2 Phase 4, 1 Early Phase 1.
Follow Infertility Unexplained: new trials by email Literature Review of Infertility Unexplained trials Research Report on Infertility Unexplained
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Autologous Decidual-like Natural Killer Cells Therapy for Reproductive Failure NK cell perfusion group - Abortion, Missed, Infertility Unexplained | Phase 2 | Not yet recruiting | The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School | 159 | 2025-11-01 | 2025-11-17 |
| Autologous Decidual-like Natural Killer Cells Therapy for Infertility or Adverse Pregnancy History autologous decidual-like NK cells - Abortion, Habitual, Infertility Unexplained | Phase 1 | Recruiting | The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School | 14 | 2025-02-13 | 2025-11-17 |
| Biological Aging Hallmarks-Guided Integrative TCM and Conventional Medicine in Post-Treatment Unexplained Female Infertility 1. Aging Hallmarks Biomarker Profiling (Telomere-Based), 2. Integrative Botanical and Nutraceutical Intervention, 3. Natural Conception or Assisted Reproductive Technologies - Idiopathic Infertility, Infertility Unexplained | Not applicable | Recruiting | BEYOND GENOMiX SA, AG, Ltd | 15 | 2025-01-01 | 2026-04-29 |
| The Role of Granulocyte Colony Stimulating Factor in Embryo Transfer Outcomes Granulocyte Colony-Stimulating Factor (Filgrastim), Standard Embryo Transfer Media - Infertility, Infertility,Female | Phase 4 | Unknown | Newlife Fertility Centre | 300 | 2024-03-20 | 2024-03-21 |
| Aftificial Inteligence in Assisted Reproductive Techniques to Assess Oocyte Quality and Embryo Ploidy arteficial inteligence evaluation of oocyte and embryo development - Infertility, Infertility, Female | Recruiting | Charles University, Czech Republic | 1000 | 2024-01-05 | 2025-01-22 | |
| Evaluation of Treatment With Coenzyme Q10 and L-Carnitine on Semen Parameters in Infertile Men With Idiopathic Oligoasthenoteratospermia co enzyme Q10 , L- Carnitine - Infertility Unexplained, Oligospermia | Early Phase 1 | Unknown | Ain Shams University | 120 | 2023-06-15 | 2024-04-02 |
| Endometriosis and Peritoneal Dysbiosis Next Generation Sequencing (NGS) - Endometriosis, Infertility Unexplained | Not applicable | Recruiting | Jagiellonian University | 100 | 2023-05-01 | 2025-04-15 |
| Luteal Phase Support in IUI MOH Treatment Luteal Phase Support in IUI MOH Treatment Progesterone Vaginal Product, Placebo - Pregnancy Related, Fertility Issues | Phase 4 | Recruiting | UMC Utrecht | 1008 | 2023-03-01 | 2025-12-31 |
| Sperm Preparation Prior to Intrauterine Insemination Study Zymot Multi sperm separation device, Density gradient centrifugation - Infertility, Infertility Secondary | Not applicable | Recruiting | University of California, San Francisco | 270 | 2023-02-05 | 2026-09-15 |
| Only Gonadotropin Vs. Letrozole Combined Gonadotropin Stimulation in IUI Cycles Letrozole 2.5mg, Gonadotropin - Infertility Unexplained | Not applicable | Completed | Uludag University | 131 | 2023-01-01 | 2024-05-14 |
| Comparison of Recombinant Follicle Stimulating Hormone and the Combination of Recombinant Follicle Stimulating Hormone With Clomiphene Citrate in Stimulated Intrauterine Insemination Cycles Recombinant Follicle Stimulating Hormone, Recombinant Follicle Stimulating Hormone and Clomiphene Citrate - Infertility Unexplained | Not applicable | Unknown | Bezmialem Vakif University | 254 | 2023-01-01 | 2024-02-02 |
| PMA-FERTITHEQUE Biocollection Biocollection - Infertility, Infertility Unexplained | Terminated | University Hospital, Brest | 250 | 2022-11-11 | 2025-12-18 | |
| Using of Testes Shocker in Improving the Spermatogenesis and Sperms Activity Testes shocker - Infertility, Male, Infertility Unexplained | Not applicable | Unknown | University of Baghdad | 250 | 2022-09-01 | 2022-11-03 |
| Organic Pollutants in Pelvic Endometriosis Detection of PAHs in visceral fat with gas chromatography-isotope dilution mass spectrometry - Endometriosis, Infertility Unexplained | Not applicable | Completed | Jagiellonian University | 46 | 2022-07-01 | 2023-11-18 |
| Effects of Flourish HEC and BioGenesis to Improve Conception Flourish HEC and BioGenesis - Infertility, Infertility Unexplained | Phase 1 | Terminated | Vaginal Biome Science | 1 | 2022-06-15 | 2025-07-01 |
| SIRT-1 Antagonism for Endometrial Receptivity EX-527 (Selisistat), Placebo - Endometriosis, Uterine Diseases | Phase 2 | Withdrawn | Wake Forest University Health Sciences | 2022-01-01 | 2021-11-17 | |
| Effects of Age and Infertility on Ovarian Granulosa Cell Function Infertility, Female, Infertility Unexplained | Unknown | King's College London | 500 | 2021-07-01 | 2021-07-07 | |
| Diagnostics of Chronic Endometritis in Infertility Ofloxacin + Metronidazole - Infertility Unexplained, Abnormal Uterine Bleeding | Not applicable | Completed | Jagiellonian University | 102 | 2021-04-01 | 2025-04-18 |
| Relation Between MicroRNA 203 and 210 and Sparing the Laparoscopic Examination in Cases of Unexplained Infertility Laparoscopic Exploration, Estimation of Plasma Expression level of MICRO RNA 203 & 210 - Infertility Unexplained, Endometriosis | Not applicable | Completed | Benha University | 100 | 2020-11-07 | 2023-01-11 |
| Modulation of Reproductive Microbiota by Ligilactobacillus Salivarius CECT5713 Ligilactobacillus salivarius CECT5713, Placebo - Infertility Unexplained | Not applicable | Completed | Biosearch S.A. | 72 | 2020-09-01 | 2024-03-04 |
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Infertility (17) · Infertility, Female (8) · Infertility, Male (6) · Endometriosis (4) · Asthenozoospermia (2) · Oligospermia (2) · Abortion, Habitual (1) · Abortion, Missed (1) · Abortion, Spontaneous (1) · Anovulation (1) · Inflammation (1) · Menopause, Premature (1) · Metrorrhagia (1) · Mitochondrial Diseases (1) · Ovarian Dysgenesis 2 (1)
Urogenital Diseases (27) · Genital Diseases (25) · Female Urogenital Diseases and Pregnancy Complications (17) · Female Urogenital Diseases (14) · Genital Diseases, Female (14) · Genital Diseases, Male (8) · Male Urogenital Diseases (8) · Infertility (4) · Pregnancy Complications (3) · Abortion, Spontaneous (2) · Adnexal Diseases (2) · Endocrine System Diseases (2) · Gonadal Disorders (2) · Infertility, Male (2) · Ovarian Diseases (2)
Centrifugation, Density Gradient (2) · 1-phenyl-3,3-dimethyltriazene (1) · 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide (1) · Blood Specimen Collection (1) · Carnitine (1) · Clomiphene (1) · Embryonic Development (1) · Fertilization in Vitro (1) · Filgrastim (1) · Glycoprotein Hormones, alpha Subunit (1) · Gonadotropins (1) · Granulocyte Colony-Stimulating Factor (1) · Letrozole (1) · Metabolism (1) · Metronidazole (1)
Jagiellonian University (4) · University of California, San Francisco (3) · Bezmialem Vakif University (2) · The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School (2) · Ain Shams University (1) · Ascendance Biomedical (1) · BEYOND GENOMiX SA, AG, Ltd (1) · Babylon University (1) · Benha University (1) · Biosearch S.A. (1) · Charles University, Czech Republic (1) · Dokuz Eylul University (1) · King's College London (1) · Nefise Nazlı YENIGUL (1) · Newlife Fertility Centre (1)
United States (6) · Turkey (Türkiye) (5) · Poland (4) · Egypt (2) · Iraq (2) · Spain (2) · Belgium (1) · Canada (1) · China (1) · Czechia (1) · France (1) · Netherlands (1) · Switzerland (1)
Yali Hu (2) · Abdul Razzaq A. Alsalman, PhD (1) · Abdulsamie H Alta'ee, PhD (1) · Aimee Eyvazzadeh, MD, MS, MBA (1) · Alessa N Sugihara, MD (1) · Bruce A Lessey, MD, PhD (1) · E Scott Sills, MD PhD (1) · Gurkan Uncu, Prof. (1) · Hashim Talib T Hashim, MBChB (1) · Hui Zhu (1) · Iwona Gawron, Ph.D. (1) · Lamia A. Almashhedy, PhD (1)
PMID 29486615, PMID 30796792, PMID 31710193, PMID 32195207, PMID 34070761, PMID 35522187, PMID 37265937, PMID 40754175, PMID 41263858, PMID 42334867
R01HD084380 (1)