15 completed, 12 recruiting, 8 unknown, 1 active not recruiting. 9 Phase 2, 7 Not applicable, 3 Phase 3, 3 Phase 4.
Follow Immune Complex Diseases: new trials by email Literature Review of Immune Complex Diseases trials Research Report on Immune Complex Diseases
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| I-FABP as a Predictor of Gastrointestinal Involvement in Pediatric IgA Vasculitis Plasma I-FABP Measurement - IgA Vasculitis, Gastrointestinal Involvement | Recruiting | Bursa City Hospital | 100 | 2026-05-15 | 2026-06-24 | |
| Telitacicept in the Treatment of Pediatric IgA Vasculitis-Associated Nephritis Collect clinical data from the patients., This study exclusively prospectively collected clinical data from the patients and did not involve any therapeutic interventions - IgAVN, IgA Vasculitis | Not yet recruiting | The Children's Hospital of Zhejiang University School of Medicine | 300 | 2026-01-01 | 2026-01-21 | |
| Study of Ravulizumab in Pediatric Participants With Primary IgAN Ravulizumab - IgAN, IgAVN | Phase 3 | Recruiting | Alexion Pharmaceuticals, Inc. | 36 | 2025-06-14 | 2026-07-30 |
| Which of the Commonly Available and Approved Drugs in Addition to Standard of Care Can Significantly Improve the Slope of Estimated Glomerular Filtration Rate at Two Years When Compared to Standard of Care Alone in South-Asian Kidney Biopsy-proven Adult (≥18 Years) Primary IgA Nephropathy? Oral prednisolone and SoC, Gut-directed budesonide and SoC, Mycophenolate mofetil (MMF) and SoC - IgA Nephropathy, Renal Insufficiency, Chronic | Phase 4 | Recruiting | Christian Medical College, Vellore, India | 585 | 2025-02-15 | 2025-07-14 |
| Rheumatoid Purpura in Children: a Multicenter Observational Study of Pediatric Emergency Department Management and Follow-up by Primary Care Physicians Management of rheumatoid purpura - Rheumatoid Purpura | Completed | Groupe Hospitalier de la Region de Mulhouse et Sud Alsace | 66 | 2023-05-09 | 2025-11-20 | |
| Mycophenolate Mofetil in Gastrointestinal Henoch-Schonlein Purpura MMF - Henoch-Schönlein Purpura, Gastrointestinal Injury | Not applicable | Recruiting | Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University | 24 | 2023-01-01 | 2023-07-19 |
| Leflunomide for Henoch-Schonlein Purpura Leflunomide - Henoch-Schonlein Purpura | Not applicable | Recruiting | Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University | 36 | 2023-01-01 | 2023-07-10 |
| (Summit) A Study to Evaluate the Efficacy and Safety of CGT9486 Versus Placebo in Patients With Indolent or Smoldering Systemic Mastocytosis Bezuclastinib Tablets (Formulation A), Bezuclastinib Tablets (Formulation B), Placebo Tablets - SSM, Mastocytosis, Indolent | Phase 2 | Active not recruiting | Cogent Biosciences, Inc. | 237 | 2022-06-27 | 2026-10-22 |
| Evaluation of Glucocorticoids Plus Rituximab in Patients With Newly-Diagnosed or Relapsing IgA Vasculitis Rituximab Injection, placebo - IgA Vasculitis | Phase 3 | Completed | Hopital Foch | 75 | 2022-03-11 | 2026-06-11 |
| (Apex) Bezuclastinib in Patients With Advanced Systemic Mastocytosis bezuclastinib - Advanced Systemic Mastocytosis (AdvSM), SM With an Associated Hematologic Neoplasm (SM-AHN) | Phase 2 | Recruiting | Cogent Biosciences, Inc. | 140 | 2021-11-09 | 2026-09-15 |
| Study of Sparsentan Treatment in Pediatrics With Proteinuric Glomerular Diseases Sparsentan - Focal Segmental Glomerulosclerosis, Minimal Change Disease | Phase 2 | Recruiting | Travere Therapeutics, Inc. | 67 | 2021-08-12 | 2026-05-12 |
| Biologics in Refractory Vasculitis: A Trial of Biologic Therapy for Refractory Primary Non-ANCA Associated Vasculitis Rituximab, Infliximab, Tocilizumab - Giant Cell Arteritis, Takayasu Arteritis | Phase 2 | Terminated | Cambridge University Hospitals NHS Foundation Trust | 22 | 2021-07-14 | 2025-06-17 |
| Validation of the IgA1 Detection Method With Gradient Glycosylation by Mass Spectrometry as a Potential Marker of Renal Involvement in Pediatric Rheumatoid Purpura Mass Sepctrometry - Rheumatoid Purpura, Pediatric ALL | Completed | Centre Hospitalier Universitaire de Nīmes | 52 | 2020-10-22 | 2023-02-08 | |
| The Therapeutic Value and Mechanism of Recombinant Human Interleukin-2 in Children With Henoch-schönlein Purpura IL-2 - Purpura, Schoenlein-Henoch | Not applicable | Completed | The First Hospital of Jilin University | 59 | 2020-06-14 | 2022-08-18 |
| Efficacy of Colchicine to Prevent Skin Relapses in Adult's IgA Vasculitis Colchicine - IgA Vasculitis | Phase 3 | Unknown | Assistance Publique - Hôpitaux de Paris | 264 | 2019-11-12 | 2021-10-04 |
| Clinical Study on Strategy for Refractory Henoch-Schönlein Purpura Methylprednisolone, IVIG, other basic supportive treatment - Henoch-Schönlein Purpura | Not applicable | Recruiting | Children's Hospital of Fudan University | 150 | 2019-09-01 | 2025-02-19 |
| Journey of Patients With Vasculitis From First Symptom to Diagnosis Online Questionnaire - Vasculitis, Systemic Vasculitis | Completed | University of Pennsylvania | 456 | 2018-01-11 | 2018-06-06 | |
| Flu Vaccine Response in Patients on Biologic Therapies Influenza vaccine - Rheumatologic Disorder, Inflammatory Bowel Diseases | Phase 2 | Completed | Stony Brook University | 30 | 2017-11-03 | 2026-08-06 |
| Clinical Transcriptomics in Systemic Vasculitis (CUTIS) Cryoglobulinemic Vasculitis (CV), Drug-induced Vasculitis | Recruiting | Peter Merkel | 50 | 2017-01-01 | 2026-01-22 | |
| A Randomized Multicenter Study for Isolated Skin Vasculitis Colchicine, Dapsone, Azathioprine - Primary Cutaneous Vasculitis, Cutaneous Polyarteritis Nodosa | Phase 2 | Recruiting | University of Pennsylvania | 90 | 2017-01-01 | 2026-08-20 |
Showing 20 of 38. Sign in to see all of them.
IgA Vasculitis (33) · Polyarteritis Nodosa (10) · Granulomatosis with Polyangiitis (9) · Takayasu Arteritis (9) · Churg-Strauss Syndrome (8) · Giant Cell Arteritis (8) · Microscopic Polyangiitis (8) · Vasculitis (8) · Behcet Syndrome (6) · Vasculitis, Central Nervous System (6) · Cryoglobulinemia, Familial Mixed (5) · Glomerulonephritis, IGA (5) · Hematologic Diseases (3) · Immune System Diseases (3)
Skin and Connective Tissue Diseases (37) · Hypersensitivity (36) · Hemic and Lymphatic Diseases (35) · Immune System Diseases (35) · Pathologic Processes (35) · Pathological Conditions, Signs and Symptoms (35) · Skin Diseases (35) · Vascular Diseases (35) · Cardiovascular Diseases (34) · Blood Coagulation Disorders (33) · Hemorrhage (33) · Hemorrhagic Disorders (33) · Hemostatic Disorders (33) · Purpura (33)
Methylprednisolone (3) · Colchicine (2) · Cyclophosphamide (2) · Dapsone (2) · Mycophenolic Acid (2) · Prednisolone (2) · Rituximab (2) · Angiotensin Receptor Antagonists (1) · Antilymphocyte Serum (1) · Azathioprine (1) · Blood Specimen Collection (1) · Cyclosporine (1) · Dexamethasone (1) · Filgrastim (1) · Hemoperfusion (1)
University of Pennsylvania (4) · University of South Florida (4) · Assistance Publique - Hôpitaux de Paris (3) · Centre Hospitalier Universitaire de Nīmes (2) · Cogent Biosciences, Inc. (2) · Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University (2) · Alexion Pharmaceuticals, Inc. (1) · Bursa City Hospital (1) · Cambridge University Hospitals NHS Foundation Trust (1) · Children's Hospital of Fudan University (1) · Christian Medical College, Vellore, India (1) · Fairview University Medical Center (1) · Groupe Hospitalier de la Region de Mulhouse et Sud Alsace (1) · Hopital Foch (1) · Liaoning University of Traditional Chinese Medicine (1)
United States (16) · France (10) · China (9) · Canada (5) · Germany (4) · Italy (4) · Spain (4) · United Kingdom (4) · Netherlands (3) · Poland (3) · Australia (2) · Belgium (2) · Japan (2) · Norway (2) · Switzerland (2)
Amanda M. Terry, MA (3) · Peter A Merkel, MD, MPH (3) · Peter A. Merkel, MD, MPH (3) · Christian Pagnoux, MD, MPH, MSc (2) · Megan Clowse, MD, MPH (2) · Peter C. Grayson, MD (2) · Robert Micheletti, MD (2) · Weiping Tan, PhD (2) · Aihua Zhang, M.D. (1) · Antoine Sreih, MD (1) · Arne Slungaard (1) · Christy A Beneri, DO (1) · Cord Sunderkoetter, Prof Dr MD (1) · David Jayne (1)
PMID 36853224, PMID 42384439, PMID 11961015, PMID 12241872, PMID 12401245, PMID 15947991, PMID 20505654, PMID 20852275, PMID 21626222, PMID 28605168, PMID 31377786, PMID 32345372, PMID 33734346, PMID 34463932, PMID 34853411, PMID 38724717, PMID 38825350, PMID 38825354, PMID 40042623, PMID 40214779, PMID 40225367, PMID 40938675
U54AR057319 (3), 2018 (1)