3 recruiting, 2 completed, 2 unknown, 1 active not recruiting. 9 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 9 | Recruiting 3, Completed 2, Unknown 2, Active not recruiting 1, Terminated 1 |
Follow Immune Complex Diseases: new trials by email Literature Review of Immune Complex Diseases trials Research Report on Immune Complex Diseases
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| (Summit) A Study to Evaluate the Efficacy and Safety of CGT9486 Versus Placebo in Patients With Indolent or Smoldering Systemic Mastocytosis Bezuclastinib Tablets (Formulation A), Bezuclastinib Tablets (Formulation B), Placebo Tablets - SSM, Mastocytosis, Indolent | Phase 2 | Active not recruiting | Cogent Biosciences, Inc. | 237 | 2022-06-27 | 2026-10-22 |
| (Apex) Bezuclastinib in Patients With Advanced Systemic Mastocytosis bezuclastinib - Advanced Systemic Mastocytosis (AdvSM), SM With an Associated Hematologic Neoplasm (SM-AHN) | Phase 2 | Recruiting | Cogent Biosciences, Inc. | 140 | 2021-11-09 | 2026-09-15 |
| Study of Sparsentan Treatment in Pediatrics With Proteinuric Glomerular Diseases Sparsentan - Focal Segmental Glomerulosclerosis, Minimal Change Disease | Phase 2 | Recruiting | Travere Therapeutics, Inc. | 67 | 2021-08-12 | 2026-05-12 |
| Biologics in Refractory Vasculitis: A Trial of Biologic Therapy for Refractory Primary Non-ANCA Associated Vasculitis Rituximab, Infliximab, Tocilizumab - Giant Cell Arteritis, Takayasu Arteritis | Phase 2 | Terminated | Cambridge University Hospitals NHS Foundation Trust | 22 | 2021-07-14 | 2025-06-17 |
| Flu Vaccine Response in Patients on Biologic Therapies Influenza vaccine - Rheumatologic Disorder, Inflammatory Bowel Diseases | Phase 2 | Completed | Stony Brook University | 30 | 2017-11-03 | 2026-08-06 |
| A Randomized Multicenter Study for Isolated Skin Vasculitis Colchicine, Dapsone, Azathioprine - Primary Cutaneous Vasculitis, Cutaneous Polyarteritis Nodosa | Phase 2 | Recruiting | University of Pennsylvania | 90 | 2017-01-01 | 2026-08-20 |
| The Research of Standard Diagnosis and Treatment for Severe HSP in Children Dexamethasone, Gamma globulin, Hemoperfusion - Henoch-Schoenlein Purpura | Phase 2 | Unknown | Nanjing Children's Hospital | 30 | 2015-08-01 | 2020-02-26 |
| Research on the Blood- Cooling - Toxin - Removing - Stasis - Dispersing Protocol Evaluation of Hench-schonlein Purpura Placebo, "ziying" granules - Purpura, Schoenlein-Henoch | Phase 2 | Unknown | Liaoning University of Traditional Chinese Medicine | 256 | 2009-11-01 | 2010-09-08 |
| Absorption of Corticosteroids in Children With Juvenile Dermatomyositis Methylprednisolone, Prednisolone - Vasculitis, Hypersensitivity, Connective Tissue Diseases | Phase 2 | Completed | Northwestern University | 6 | 1997-09-01 | 2011-07-22 |
IgA Vasculitis (5) · Hematologic Diseases (2) · Hypersensitivity (2) · Immune System Diseases (2) · Mastocytosis (2) · Mastocytosis, Systemic (2) · Vasculitis (2) · Cardiovascular Diseases (1) · Cogan Syndrome (1) · Collagen Diseases (1) · Connective Tissue Diseases (1) · Cryoglobulinemia, Familial Mixed (1) · Dermatomyositis (1) · Giant Cell Arteritis (1)
Skin and Connective Tissue Diseases (8) · Hemic and Lymphatic Diseases (7) · Hypersensitivity (7) · Immune System Diseases (7) · Pathologic Processes (7) · Pathological Conditions, Signs and Symptoms (7) · Skin Diseases (6) · Skin Diseases, Vascular (6) · Vascular Diseases (6) · Blood Coagulation Disorders (5) · Cardiovascular Diseases (5) · Hematologic Diseases (5) · Hemorrhage (5) · Hemorrhagic Disorders (5)
Azathioprine (1) · Colchicine (1) · Dapsone (1) · Dexamethasone (1) · Hemoperfusion (1) · Infliximab (1) · Influenza Vaccines (1) · Methylprednisolone (1) · Prednisolone (1) · Rituximab (1) · gamma-Globulins (1) · sparsentan (1) · tocilizumab (1)
Cogent Biosciences, Inc. (2) · Cambridge University Hospitals NHS Foundation Trust (1) · Liaoning University of Traditional Chinese Medicine (1) · Nanjing Children's Hospital (1) · Northwestern University (1) · Stony Brook University (1) · Travere Therapeutics, Inc. (1) · University of Pennsylvania (1)
United States (6) · United Kingdom (4) · Canada (3) · Germany (3) · Italy (3) · Netherlands (3) · Poland (3) · Spain (3) · Australia (2) · Belgium (2) · China (2) · France (2) · Norway (2) · Switzerland (2) · Austria (1)
Aihua Zhang, M.D. (1) · Christian Pagnoux, MD, MPH, MSc (1) · Christy A Beneri, DO (1) · David Jayne (1) · Lauren M. Pachman, MD (1) · Rachael Easton, MD, Ph.D. (1) · Rachael Easton, MD, PhD (1) · Radko Komers, MD, PhD (1) · Robert Micheletti, MD (1)
PMID 36853224, PMID 32345372, PMID 38724717, PMID 40938675, PMID 42384439
U54AR057319 (1)