63 terminated. 63 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 63 | Terminated 63 |
Follow Hypersensitivity: new trials by email Literature Review of Hypersensitivity trials Research Report on Hypersensitivity
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Dupilumab De-escalation in Pediatric Atopic Dermatitis Dupilumab - Discontinuation, Dupilumab - Dose Reduction, Dupilumab - Standard Dose - Atopic Dermatitis | Phase 4 | Terminated | Johns Hopkins University | 1 | 2024-04-01 | 2026-10-19 |
| Tralokinumab for Dupilumab Failures tralokinumab - Atopic Dermatitis | Phase 4 | Terminated | Psoriasis Treatment Center of Central New Jersey | 7 | 2023-09-11 | 2026-05-22 |
| The Purpose of This Study is to Evaluate the Effects of Ruxolitinib Cream on Adults With Atopic Dermatitis Experiencing Sleep Disturbance. ruxolitinib cream - Atopic Dermatitis | Phase 4 | Terminated | Incyte Corporation | 47 | 2023-03-16 | 2025-12-19 |
| Use of CXCL9 as a Biomarker of Acthar Efficacy Acthar gel - Sarcoidosis | Phase 4 | Terminated | University of California, San Francisco | 2 | 2022-11-03 | 2026-04-30 |
| Oral Penicillin Challenge and Allergy De-labeling in Children Amoxicillin 500mg - Penicillin Allergy | Phase 4 | Terminated | Phoenix Children's Hospital | 31 | 2022-09-26 | 2024-06-14 |
| Improvement In Scratch Behavior And Sleep In Patients With Atopic Dermatitis Crisaborole 2%, Vehicle treatment, Accelerometry device for children - Atopic Dermatitis | Phase 4 | Terminated | Boston University | 72 | 2022-07-26 | 2025-03-14 |
| Step-up to Medium Strength Triple Therapy vs High Strength ICS/LABA in Adult Asthmatics Uncontrolled on Medium Strength ICS/LABA Administration via pressurized metered dose inhaler (pMDI) - Asthma | Phase 4 | Terminated | Chiesi Farmaceutici S.p.A. | 320 | 2022-02-25 | 2024-11-15 |
| Protection From Food Induced Anaphylaxis by Reducing the Serum Level of Specific IgE (Protana). Omalizumab Injection - Food Allergy | Phase 4 | Terminated | Carsten Bindslev-Jensen | 7 | 2019-07-01 | 2023-12-11 |
| The Effect of NAC on Lung Function and CT Mucus Score n-acetylcystine + albuterol, 0.9% saline + albuterol - Asthma | Phase 4 | Terminated | University of California, San Francisco | 4 | 2019-02-20 | 2026-06-11 |
| Comparison of Dexamethasone Oral Preparations to Assess Taste and Acceptance in Children With Asthma and Croup Dexamethasone IV for PO, Dexamethasone crushed tablets - Asthma, Croup | Phase 4 | Terminated | Vanderbilt University Medical Center | 40 | 2018-10-23 | 2021-11-08 |
| Reducing Exercise-induced Bronchoconstriction in Children With Asthma and Obesity Albuterol Sulfate, Interval Warm-up exercise - Asthma in Children, Obesity, Childhood | Phase 4 | Terminated | University of Nevada, Las Vegas | 34 | 2018-09-18 | 2021-07-22 |
| Comparison of Albuterol for Status Asthmaticus preservative free albuterol - Status Asthmaticus | Phase 4 | Terminated | Norton Healthcare | 8 | 2018-09-10 | 2021-05-20 |
| Effect of Dupilumab (Anti-IL4Rα) on the Host-Microbe Interface in Atopic Dermatitis Dupilumab, Placebo - Atopic Dermatitis (AD) | Phase 4 | Terminated | National Institute of Allergy and Infectious Diseases (NIAID) | 72 | 2018-07-25 | 2021-10-04 |
| Inpatient Clinical Trial of NAC N-acetylcysteine - Asthma | Phase 4 | Terminated | University of California, San Francisco | 1 | 2018-07-06 | 2021-10-26 |
| A Study of Crisaborole Ointment 2%; Crisaborole Vehicle; TCS and TCI in Subjects Aged ≥ 2 Years, With Mild-moderate AD Crisaborole ointment, 2%, Hydrocortisone butyrate cream, 0.1%, Pimecrolimus cream, 1% - Atopic Dermatitis | Phase 4 | Terminated | Pfizer | 237 | 2018-04-27 | 2022-01-10 |
| Targeted AntiBiotics for Chronic Pulmonary Diseases Piperacillin/tazobactam, Ciprofloxacin - COPD, Respiratory Tract Infections | Phase 4 | Terminated | Chronic Obstructive Pulmonary Disease Trial Network, Denmark | 51 | 2018-01-10 | 2023-05-25 |
| Can Vitamin D Treatment Help Treat Moderate to Severe Atopic Dermatitis in Young Children? the D-Vex Pilot Study Stoss vitamin D, Daily vitamin D, Stoss placebo - Atopic Dermatitis | Phase 4 | Terminated | Murdoch Childrens Research Institute | 13 | 2017-10-16 | 2025-03-14 |
| PRISTINE - Personalised Approach to Improve aSThma prescrIbing iN childrEn Montelukast or Salmeterol or Theophylline or Steroid - Asthma | Phase 4 | Terminated | Brighton and Sussex University Hospitals NHS Trust | 2 | 2017-07-01 | 2019-12-18 |
| An Imaging Study Using PET/CT to Characterize the Effect of Intravenous Reslizumab on Airway Inflammation Reslizumab, Fludeoxyglucose F 18 (FDG), Placebo - Asthma | Phase 4 | Terminated | Teva Branded Pharmaceutical Products R&D, Inc. | 5 | 2017-05-08 | 2021-11-09 |
| Steroids in Children Hospitalized With Asthma Dexamethasone, Prednisone - Asthma, Status Asthmaticus | Phase 4 | Terminated | University of Florida | 6 | 2017-03-20 | 2019-06-21 |
Showing 20 of 63. Sign in to see all of them.
Asthma (35) · Dermatitis, Atopic (12) · Sarcoidosis (3) · Anaphylaxis (2) · Asthma, Exercise-Induced (2) · Pulmonary Disease, Chronic Obstructive (2) · Rhinitis, Allergic, Perennial (2) · Rhinitis, Allergic, Seasonal (2) · Status Asthmaticus (2) · Angioedema (1) · Angioedemas, Hereditary (1) · Aspergillosis, Allergic Bronchopulmonary (1) · Bronchiectasis (1) · Conjunctivitis, Allergic (1)
Immune System Diseases (63) · Hypersensitivity, Immediate (59) · Respiratory Hypersensitivity (42) · Respiratory Tract Diseases (42) · Bronchial Diseases (37) · Lung Diseases (36) · Lung Diseases, Obstructive (35) · Skin Diseases (16) · Skin and Connective Tissue Diseases (16) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (14) · Genetic Diseases, Inborn (14) · Skin Diseases, Genetic (12) · Dermatitis (11) · Skin Diseases, Eczematous (11)
Fluticasone (5) · Mometasone Furoate (5) · Albuterol (4) · Fluticasone-Salmeterol Drug Combination (4) · montelukast (4) · Acetylcysteine (3) · Budesonide (3) · Omalizumab (3) · Sodium Chloride (3) · pimecrolimus (3) · Adrenal Cortex Hormones (2) · Azithromycin (2) · Calcium Dobesilate (2) · Ciprofloxacin (2) · Dexamethasone (2)
University of California, San Francisco (5) · Organon and Co (4) · Novartis Pharmaceuticals (3) · University of Chicago (3) · GlaxoSmithKline (2) · Johns Hopkins University (2) · Teva Branded Pharmaceutical Products R&D, Inc. (2) · University of Alberta (2) · Vanderbilt University Medical Center (2) · Apieron (1) · Boehringer Ingelheim (1) · Boston Children's Hospital (1) · Boston University (1) · Brighton and Sussex University Hospitals NHS Trust (1) · CSA Medical, Inc. (1)
United States (39) · United Kingdom (5) · Germany (4) · Canada (3) · Netherlands (3) · Denmark (2) · Italy (2) · Australia (1) · Belgium (1) · Hungary (1) · Japan (1) · Poland (1) · Sweden (1) · Switzerland (1)
Irvin Mayers, MD, FRCPC (2) · John Fahy, M.D, M.Sc. (2) · Alyssa H Silver, MD (1) · Brian Lipworth, MD (1) · Carsten Bindslev-Jensen, ProfDrMedPhd (1) · Charlotte G. Moertz, ProfMDPhd (1) · Chrsitopher Compton (1) · Cornelis Wortel, MD, PhD (1) · Daniel Martin, M.D. (1) · Dharini M Bhammar, Ph.D. (1) · Diana S. Lee, MD (1) · Diane E Hindman, MD PharmD (1) · Donald Arnold, MD, MPH (1) · Edmund Volkerts, PhD (1)
PMID 16680006, PMID 18385500, PMID 18951618, PMID 20070141, PMID 20674827, PMID 20819468, PMID 22805051, PMID 22920495, PMID 22951056, PMID 23374261, PMID 24267370, PMID 26302738, PMID 26598458, PMID 27560168, PMID 31238116, PMID 34303860, PMID 35124256, PMID 36596609, PMID 38844921
2009 (1), 2014 (1), 2015 (1), 2017 (1), 2018 (1), P01HL128191 (1), U10HL064287 (1), U10HL064288 (1), U10HL064295 (1), U10HL064305 (1), U10HL064307 (1), U10HL064313 (1), U19AI117673 (1)