4 completed, 2 unknown. 6 Phase 3, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 6 | Completed 4, Unknown 2 |
| Phase 2 | 1 | Unknown 1 |
Follow Hydatidiform Mole: new trials by email Literature Review of Hydatidiform Mole trials Research Report on Hydatidiform Mole
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Second Uterine Evacuation for Low-risk Gestational Trophoblastic Neoplasia Uterine curettage, Chemotherapy - Gestational Trophoblastic Neoplasia, Molar Pregnancy | Phase 3 | Unknown | Brigham and Women's Hospital | 150 | 2021-02-11 | 2022-05-27 |
| Letrozole as a Prophylaxis From GTN for Complete Mole Patients Suction evacuation, Letrozole tablets - Gestational Trophoblastic Disease | Phase 2 / Phase 3 | Unknown | Zagazig University | 200 | 2020-06-01 | 2022-07-12 |
| Dactinomycin or Methotrexate in Treating Patients With Low-Risk Gestational Trophoblastic Neoplasia Dactinomycin, Leucovorin Calcium, Methotrexate - Choriocarcinoma, FIGO Stage I Gestational Trophoblastic Tumor | Phase 3 | Completed | GOG Foundation | 57 | 2012-06-18 | 2022-08-12 |
| RCT on the Efficacy of Methotrexate for the Prevention of GTD Methotrexate, Vitamin B Complex - Hydatidiform Mole | Phase 3 | Completed | University of the Philippines | 99 | 2011-12-01 | 2020-04-17 |
| Amifostine in Treating Peripheral Neuropathy in Patients Who Have Received Chemotherapy for Cancer amifostine trihydrate - Gestational Trophoblastic Tumor, Neurotoxicity | Phase 3 | Completed | Gynecologic Oncology Group | 100 | 2003-03-01 | 2013-07-09 |
| Methotrexate Compared With Dactinomycin in Treating Patients With Gestational Trophoblastic Neoplasia Dactinomycin, Methotrexate - Good Prognosis Metastatic Gestational Trophoblastic Tumor, Hydatidiform Mole | Phase 3 | Completed | Gynecologic Oncology Group | 240 | 1999-06-01 | 2018-05-15 |
Gestational Trophoblastic Disease (3) · Choriocarcinoma (1) · Neurotoxicity Syndromes (1) · Peripheral Nervous System Diseases (1)
Female Urogenital Diseases and Pregnancy Complications (6) · Neoplasms (6) · Neoplasms by Histologic Type (6) · Neoplasms, Germ Cell and Embryonal (6) · Pregnancy Complications (6) · Pregnancy Complications, Neoplastic (6) · Trophoblastic Neoplasms (6) · Urogenital Diseases (6) · Gestational Trophoblastic Disease (3) · Adenocarcinoma (1) · Carcinoma (1) · Chemically-Induced Disorders (1) · Neoplasms, Glandular and Epithelial (1) · Nervous System Diseases (1) · Neuromuscular Diseases (1)
Methotrexate (3) · Dactinomycin (2) · Vacuum Curettage (2) · merphos (2) · Amifostine (1) · Drug Therapy (1) · Letrozole (1) · Leucovorin (1) · Vitamin B Complex (1)
Gynecologic Oncology Group (2) · Brigham and Women's Hospital (1) · GOG Foundation (1) · University of the Philippines (1) · Zagazig University (1)
United States (3) · Brazil (1) · Canada (1) · Egypt (1) · Japan (1) · Philippines (1) · South Korea (1) · United Kingdom (1)
Agnes L. Soriano-Estrella, MD (1) · Antonio Braga, MD, PhD (1) · Julian C Schink (1) · Mohamed A Alabiad, MD (1) · Raymond Osborne (1) · Steven C. Plaxe, MD (1)
U10CA027469 (2), U10CA180868 (1)