7 completed, 4 unknown, 3 recruiting, 2 active not recruiting. 6 Phase 3, 3 Phase 2, 2 Not applicable, 1 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 6 | Completed 4, Unknown 2 |
| Phase 2 | 3 | Completed 2, Unknown 1 |
| Not applicable | 2 | Active not recruiting 1, Recruiting 1 |
| Phase 4 | 1 | Unknown 1 |
Follow Hydatidiform Mole: new trials by email Literature Review of Hydatidiform Mole trials Research Report on Hydatidiform Mole
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Multi-center Cohort Study of Hydatidiform Mole in China (CN-HM-01) No intervention - Hydatidiform Mole | Recruiting | Obstetrics & Gynecology Hospital of Fudan University | 1489 | 2025-07-09 | 2025-10-02 | |
| A Cohort Study of Hydatidiform Mole No intervention - Hydatidiform Mole | Not yet recruiting | Women's Hospital School Of Medicine Zhejiang University | 800 | 2022-12-01 | 2022-12-08 | |
| The Accuracy of Ultrasound Diagnosis of Hydatidiform Moles Hydatidiform Mole (Diagnosis), Abortion, Spontaneous | Unknown | King's College Hospital NHS Trust | 500 | 2021-10-19 | 2024-06-11 | |
| Second Uterine Evacuation for Low-risk Gestational Trophoblastic Neoplasia Uterine curettage, Chemotherapy - Gestational Trophoblastic Neoplasia, Molar Pregnancy | Phase 3 | Unknown | Brigham and Women's Hospital | 150 | 2021-02-11 | 2022-05-27 |
| Biweekly Actinomycin-D Treatment or Multi-day Methotrexate Protocol in Low-risk Gestational Trophoblastic Neoplasia Methotrexate, Leucovorin, Dactinomycin - Gestational Trophoblastic Tumor, Gestational Trophoblastic Neoplasia | Not applicable | Active not recruiting | xiang yang | 228 | 2020-09-29 | 2025-08-11 |
| Letrozole as a Prophylaxis From GTN for Complete Mole Patients Suction evacuation, Letrozole tablets - Gestational Trophoblastic Disease | Phase 2 / Phase 3 | Unknown | Zagazig University | 200 | 2020-06-01 | 2022-07-12 |
| Study of Different Therapeutic Strategies in Hydatidiform Mole With Lung Nodule Follow up, chemotherapy - Hydatidiform Mole, Gestational Trophoblastic Neoplasia | Not applicable | Recruiting | Women's Hospital School Of Medicine Zhejiang University | 30 | 2018-12-24 | 2026-03-16 |
| BioThrax® (Anthrax) Vaccine in Pregnancy Registry Observational Intervention - Pregnancy Complications, Pregnancy Outcome | Completed | Emergent BioSolutions | 98 | 2012-07-01 | 2024-03-15 | |
| Dactinomycin or Methotrexate in Treating Patients With Low-Risk Gestational Trophoblastic Neoplasia Dactinomycin, Leucovorin Calcium, Methotrexate - Choriocarcinoma, FIGO Stage I Gestational Trophoblastic Tumor | Phase 3 | Completed | GOG Foundation | 57 | 2012-06-18 | 2022-08-12 |
| A Comparison of Single Versus Double Evacuation for Treatment of Hydatidiform Mole Suction and evacuation - Hydatidiform Mole | Phase 4 | Unknown | Nilratan Sircar Medical College | 120 | 2012-06-01 | 2016-03-23 |
| RCT on the Efficacy of Methotrexate for the Prevention of GTD Methotrexate, Vitamin B Complex - Hydatidiform Mole | Phase 3 | Completed | University of the Philippines | 99 | 2011-12-01 | 2020-04-17 |
| Second Curettage in Treating Patients With Persistent Non-metastatic Gestational Trophoblastic Tumors Laboratory Biomarker Analysis, Therapeutic Conventional Surgery - Complete Hydatidiform Mole, Non-Metastatic Gestational Trophoblastic Tumor | Phase 2 | Completed | Gynecologic Oncology Group | 64 | 2007-10-09 | 2017-08-24 |
| A Trial for Patients With Gestational Trophoblastic Disease Pemetrexed - Trophoblastic Neoplasms, Uterine Neoplasms | Phase 2 | Completed | Eli Lilly and Company | 50 | 2006-07-01 | 2007-08-09 |
| Amifostine in Treating Peripheral Neuropathy in Patients Who Have Received Chemotherapy for Cancer amifostine trihydrate - Gestational Trophoblastic Tumor, Neurotoxicity | Phase 3 | Completed | Gynecologic Oncology Group | 100 | 2003-03-01 | 2013-07-09 |
| Study of the Genetic and Epigenetic Causes of Recurrent Hydatidiform Moles Hydatidiform Moles | Active not recruiting | Baylor College of Medicine | 100 | 2000-11-07 | 2026-04-23 | |
| The French National Reference Centre of GTD Neoplasm, Trophoblastic, Gestational Trophoblastic Disease | Recruiting | Hospices Civils de Lyon | 25500 | 1999-11-01 | 2016-09-08 | |
| Methotrexate Compared With Dactinomycin in Treating Patients With Gestational Trophoblastic Neoplasia Dactinomycin, Methotrexate - Good Prognosis Metastatic Gestational Trophoblastic Tumor, Hydatidiform Mole | Phase 3 | Completed | Gynecologic Oncology Group | 240 | 1999-06-01 | 2018-05-15 |
Gestational Trophoblastic Disease (6) · Choriocarcinoma (4) · Abortion, Spontaneous (2) · Hydatidiform Mole, Invasive (2) · Trophoblastic Neoplasms (2) · Abortion, Incomplete (1) · Abortion, Missed (1) · Birth Weight (1) · Congenital Abnormalities (1) · Diabetes, Gestational (1) · Disease (1) · Eclampsia (1) · Fetal Death (1) · Maternal Death (1)
Female Urogenital Diseases and Pregnancy Complications (17) · Neoplasms (17) · Neoplasms by Histologic Type (17) · Neoplasms, Germ Cell and Embryonal (17) · Pregnancy Complications, Neoplastic (17) · Urogenital Diseases (17) · Pregnancy Complications (16) · Trophoblastic Neoplasms (15) · Gestational Trophoblastic Disease (11) · Adenocarcinoma (4) · Carcinoma (4) · Neoplasms, Glandular and Epithelial (4) · Pathologic Processes (2) · Pathological Conditions, Signs and Symptoms (2) · Body Weight (1)
Methotrexate (5) · Dactinomycin (3) · Vacuum Curettage (3) · Drug Therapy (2) · Leucovorin (2) · merphos (2) · Amifostine (1) · Letrozole (1) · Pemetrexed (1) · Suction (1) · Vitamin B Complex (1)
Gynecologic Oncology Group (3) · Women's Hospital School Of Medicine Zhejiang University (2) · Baylor College of Medicine (1) · Brigham and Women's Hospital (1) · Eli Lilly and Company (1) · Emergent BioSolutions (1) · GOG Foundation (1) · Hospices Civils de Lyon (1) · King's College Hospital NHS Trust (1) · Nilratan Sircar Medical College (1) · Obstetrics & Gynecology Hospital of Fudan University (1) · University of the Philippines (1) · Zagazig University (1) · xiang yang (1)
United States (7) · China (3) · Canada (2) · United Kingdom (2) · Brazil (1) · Egypt (1) · France (1) · India (1) · Japan (1) · Philippines (1) · South Korea (1)
Raymond Osborne (2) · Agnes L. Soriano-Estrella, MD (1) · Antonio Braga, MD, PhD (1) · David Miller, MD (1) · Jackie Ross, MD (1) · Julian C Schink (1) · Mohamed A Alabiad, MD (1) · Natalie Wells, MD (1) · Snehamay Chaudhuri, MD, DNB (1) · Steven C. Plaxe, MD (1) · Weiguo Lv, PhD (1) · Xin Lu, MD & PhD (1) · Xing Xie (1)
PMID 11677152, PMID 13129680, PMID 14550593, PMID 15979551, PMID 18039680, PMID 24105472, PMID 24105752, PMID 27500329, PMID 32460997, PMID 37612621, PMID 40382972, PMID 40543844
U10CA027469 (3), U10CA180868 (2)