4 completed, 4 recruiting, 2 active not recruiting, 2 unknown. 5 Phase 2, 2 Phase 3, 1 Not applicable, 1 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 5 | Completed 2, Recruiting 2, Terminated 1 |
| Phase 3 | 2 | Active not recruiting 1, Completed 1 |
| Not applicable | 1 | Active not recruiting 1 |
| Phase 1 | 1 | Completed 1 |
Follow Choriocarcinoma: new trials by email Literature Review of Choriocarcinoma trials Research Report on Choriocarcinoma
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| High-dose Chemotherapy as Second-line Drug Therapy for Relapsed Germ Cell Tumors High-dose chemotherapy (TI- 2 cycles, CE- 3 cycles ) - Germ Cell Tumor | Phase 2 | Recruiting | N.N. Petrov National Medical Research Center of Oncology | 25 | 2024-03-01 | 2025-08-03 |
| Molecular Epidemiology of Pediatric Germ Cell Tumors Questionnaire Administration, Tumor Specimen Collection, Germline DNA Samples - Germ Cell Tumor, Germinoma | Recruiting | Children's Oncology Group | 1151 | 2023-04-12 | 2025-10-24 | |
| A Study of a New Way to Treat Children and Young Adults With a Brain Tumor Called NGGCT Biospecimen Collection, Carboplatin, Etoposide - Central Nervous System Nongerminomatous Germ Cell Tumor, Choriocarcinoma | Phase 2 | Recruiting | Children's Oncology Group | 160 | 2021-07-13 | 2026-09-23 |
| Biweekly Actinomycin-D Treatment or Multi-day Methotrexate Protocol in Low-risk Gestational Trophoblastic Neoplasia Methotrexate, Leucovorin, Dactinomycin - Gestational Trophoblastic Tumor, Gestational Trophoblastic Neoplasia | Not applicable | Active not recruiting | xiang yang | 228 | 2020-09-29 | 2025-08-11 |
| Study of TRC105 and Bevacizumab in Patients With Refractory Gestational Trophoblastic Neoplasia (GTN) TRC105, Bevacizumab - Gestational Trophoblastic Neoplasia, Choriocarcinoma | Phase 2 | Terminated | Tracon Pharmaceuticals Inc. | 3 | 2016-03-01 | 2019-07-23 |
| Standard-Dose Combination Chemotherapy or High-Dose Combination Chemotherapy and Stem Cell Transplant in Treating Patients With Relapsed or Refractory Germ Cell Tumors paclitaxel, ifosfamide, cisplatin - Germ Cell Tumor, Teratoma | Phase 3 | Active not recruiting | Alliance for Clinical Trials in Oncology | 420 | 2015-08-06 | 2026-06-16 |
| TRC105 Combined With Standard-dose Bevacizumab for Two Patients With Metastatic And Refractory Choriocarcinoma TRC105, Bevacizumab - Choriocarcinoma | Phase 2 | Completed | Tracon Pharmaceuticals Inc. | 2 | 2015-01-01 | 2019-06-11 |
| Dactinomycin or Methotrexate in Treating Patients With Low-Risk Gestational Trophoblastic Neoplasia Dactinomycin, Leucovorin Calcium, Methotrexate - Choriocarcinoma, FIGO Stage I Gestational Trophoblastic Tumor | Phase 3 | Completed | GOG Foundation | 57 | 2012-06-18 | 2022-08-12 |
| Clinical Database and Biobank of Patients With Gynecologic Neoplasms Cervical Cancer, Ovarian Cancer | Unknown | Huazhong University of Science and Technology | 1600000 | 2010-01-01 | 2019-07-19 | |
| Safety and Tolerability Study of AZD2171 in Combination With AZD0530 in Patients With Advanced Solid Tumours AZD2171, AZD0530 - Neoplasms | Phase 1 | Completed | AstraZeneca | 40 | 2007-05-01 | 2010-04-15 |
| Conformation of Beta Human Chorionic Gonadotropin During Chemotherapy for Choriocarcinoma atomic force microscopy, dual polarisation interferometry - Trophoblastic Neoplasms, Choriocarcinoma | Unknown | National Taiwan University Hospital | 30 | 2006-08-01 | 2006-02-20 | |
| A Trial for Patients With Gestational Trophoblastic Disease Pemetrexed - Trophoblastic Neoplasms, Uterine Neoplasms | Phase 2 | Completed | Eli Lilly and Company | 50 | 2006-07-01 | 2007-08-09 |
| The French National Reference Centre of GTD Neoplasm, Trophoblastic, Gestational Trophoblastic Disease | Recruiting | Hospices Civils de Lyon | 25500 | 1999-11-01 | 2016-09-08 |
Teratoma (4) · Endodermal Sinus Tumor (3) · Germinoma (3) · Gestational Trophoblastic Disease (3) · Hydatidiform Mole (3) · Neoplasms, Germ Cell and Embryonal (3) · Trophoblastic Neoplasms (3) · Carcinoma, Embryonal (2) · Hydatidiform Mole, Invasive (2) · Nonseminomatous germ cell tumor (2) · Ovarian Neoplasms (2) · Seminoma (2) · Trophoblastic Tumor, Placental Site (2) · Breast Neoplasms (1)
Adenocarcinoma (13) · Carcinoma (13) · Female Urogenital Diseases and Pregnancy Complications (13) · Neoplasms by Histologic Type (13) · Neoplasms, Glandular and Epithelial (13) · Pregnancy Complications (13) · Pregnancy Complications, Neoplastic (13) · Urogenital Diseases (13) · Neoplasms (12) · Neoplasms, Germ Cell and Embryonal (10) · Trophoblastic Neoplasms (10) · Female Urogenital Diseases (3) · Genital Diseases (3) · Genital Neoplasms, Female (3) · Mesonephroma (3)
Bevacizumab (2) · Carboplatin (2) · Dactinomycin (2) · Etoposide (2) · Granulocyte Colony-Stimulating Factor (2) · Ifosfamide (2) · Leucovorin (2) · Methotrexate (2) · carotuximab (2) · Cisplatin (1) · Drug Therapy (1) · Filgrastim (1) · Magnetic Resonance Spectroscopy (1) · Mesna (1) · Microscopy, Atomic Force (1)
Children's Oncology Group (2) · Tracon Pharmaceuticals Inc. (2) · Alliance for Clinical Trials in Oncology (1) · AstraZeneca (1) · Eli Lilly and Company (1) · GOG Foundation (1) · Hospices Civils de Lyon (1) · Huazhong University of Science and Technology (1) · N.N. Petrov National Medical Research Center of Oncology (1) · National Taiwan University Hospital (1) · xiang yang (1)
United States (7) · Australia (2) · Canada (2) · China (2) · France (2) · Germany (2) · United Kingdom (2) · Belgium (1) · Denmark (1) · Ireland (1) · Italy (1) · Japan (1) · Netherlands (1) · New Zealand (1) · Russia (1)
Aleksei M Belyaev, MD,DSc,Prof. (1) · Charles Theuer, MD (1) · Charles Theuer, MD, PhD (1) · Darren Feldman, MD (1) · David Miller, MD (1) · Jane Roberston (1) · Jenny Poynter, PhD (1) · Julian C Schink (1) · Ruey-Jien Chen (1) · Shannon M MacDonald (1) · Tanja Trarbach, MD (1) · Tatyana Yu Semiglazova, MD,DSc,Prof. (1)
PMID 22503395, PMID 30563754, PMID 32460997, PMID 37612621, PMID 39028926, PMID 40382972, PMID 40543844
U10CA027469 (1), U10CA180821 (1), U10CA180868 (1), U10CA180886 (1)