2 terminated, 1 completed. 3 Phase 1, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 3 | Terminated 2, Completed 1 |
| Phase 2 | 1 | Terminated 1 |
Follow High Grade Sarcoma: new trials by email Literature Review of High Grade Sarcoma trials Research Report on High Grade Sarcoma
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Study of DCC-3014 in Combination With Avelumab in Patients With Advanced or Metastatic Sarcomas DCC-3014, Avelumab - Sarcoma, Advanced Sarcoma | Phase 1 | Completed | Memorial Sloan Kettering Cancer Center | 32 | 2020-01-22 | 2025-08-28 |
| Sapanisertib or Pazopanib Hydrochloride in Treating Patients With Locally Advanced or Metastatic Sarcoma Pazopanib, Pazopanib Hydrochloride, Sapanisertib - High Grade Sarcoma, Metastatic Leiomyosarcoma | Phase 1 / Phase 2 | Terminated | National Cancer Institute (NCI) | 151 | 2015-11-30 | 2022-08-23 |
| Adjuvant Valproate for High Grade Sarcomas Valproic Acid - High Grade Sarcoma | Phase 1 | Terminated | Columbia University | 7 | 2009-10-01 | 2015-05-21 |
Dermatofibrosarcoma (2) · Histiocytoma, Malignant Fibrous (2) · Leiomyosarcoma (2) · Liposarcoma (1) · Neurofibrosarcoma (1) · Sarcoma (1) · Sarcoma, Synovial (1)
Fibrosarcoma (2) · Histiocytoma (2) · Neoplasms (2) · Neoplasms by Histologic Type (2) · Neoplasms, Connective Tissue (2) · Neoplasms, Connective and Soft Tissue (2) · Neoplasms, Fibrous Tissue (2) · Neoplasms, Muscle Tissue (2) · Neoplasms, Adipose Tissue (1) · Neoplasms, Nerve Tissue (1) · Nerve Sheath Neoplasms (1) · Nervous System Diseases (1) · Nervous System Neoplasms (1) · Neurofibroma (1) · Neuromuscular Diseases (1)
Valproic Acid (1) · avelumab (1) · pazopanib (1) · sapanisertib (1)
Columbia University (1) · Memorial Sloan Kettering Cancer Center (1) · National Cancer Institute (NCI) (1)
United States (3)
Kevin Kalinsky, MD, MS (1) · Sandra D'Angelo, MD (1) · William D Tap (1)
U10CA180821 (1)