458 completed, 46 terminated, 34 unknown, 22 recruiting. 592 Phase 1, 111 Phase 2.
Follow Hepatitis: new trials by email Literature Review of Hepatitis trials Research Report on Hepatitis
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Phase 1 Clinical Trial of Adjuvanted Protein-based HCV Vaccine Candidates (HCV Vaccine Trial) AVIHepC1, Normal Saline - Hepatitis C | Phase 1 | Not yet recruiting | University of Alberta | 27 | 2027-01-15 | 2026-09-25 |
| A Study of LY3981314 in Participants With Autoimmune Hepatitis LY3981314 - Hepatitis Autoimmune Disease, Hepatitis | Phase 1 | Not yet recruiting | Eli Lilly and Company | 12 | 2026-12-01 | 2026-11-10 |
| A Study to Compare Blood Levels of Bepirovirsen and Safety Using Different Methods of Injecting in Healthy Adult Participants Bepirovirsen - Hepatitis B | Phase 1 | Not yet recruiting | GlaxoSmithKline | 98 | 2026-11-03 | 2026-10-29 |
| A Study of Sequential Therapy With AHB-137 Injection Followed by TVAX-008 Injection in Participants Living With Chronic Hepatitis B (CHB) AHB-137, Placebo, TVAX-008 - Chronic Hepatitis B | Phase 1 / Phase 2 | Not yet recruiting | Ausper Biopharma Co., Ltd. | 105 | 2026-10-31 | 2026-10-19 |
| A Study of Sequential Therapy With AHB-137 Injection Followed by TVAX-008 Injection in Participants Living With Chronic Hepatitis B (CHB) AHB-137, TVAX-008, Placebo - Chronic Hepatitis B | Phase 1 / Phase 2 | Not yet recruiting | Grand Theravac Life Sciences (Hangzhou) Co., Ltd. | 105 | 2026-10-31 | 2026-10-27 |
| Safety, Tolerability, Pharmacokinetic and Pharmacodynamic Characteristics of ACT500 in Participants With Metabolic Dysfunction-Associated Steatotic Liver Disease Complicated With Chronic Hepatitis B ACT500 Tablets, ACT500 Placebo Tablets - Metabolic Dysfunction-associated Steatotic Liver Disease, Chronic Hepatitis b | Phase 1 | Not yet recruiting | Xiamen Amoytop Biotech Co., Ltd. | 24 | 2026-10-30 | 2026-09-14 |
| A Clinical Study of AHB-121 in Healthy Participants and Chronic Hepatitis B (CHB) Participants AHB-121, Placebo - Chronic Hepatitis B Virus | Phase 1 | Not yet recruiting | Ausper Biopharma Co., Ltd. | 110 | 2026-10-28 | 2026-10-21 |
| Phase Ia/Ib Trial of SCTA02A Injection in Healthy Adults and Patients With Chronic Hepatitis B SCTA02A, Placebo - Hepatitis B | Phase 1 | Not yet recruiting | Sinocelltech Ltd. | 60 | 2026-10-01 | 2026-10-29 |
| A Trial to Evaluate the Efficacy and Safety of WGc0201 in Patients With Chronic Hepatitis B Virus Infection WGc0201 - Chronic Hepatitis B Virus (Hbv) | Phase 1 | Recruiting | Jiyan Liu | 9 | 2026-09-01 | 2026-07-01 |
| Study of AT-587 in Healthy Subjects AT-587, Placebo - Hepatitis E | Phase 1 | Recruiting | Atea Pharmaceuticals, Inc. | 62 | 2026-07-13 | 2026-07-27 |
| A Clinical Study Evaluating the Pharmacokinetic Characteristics and Safety of AHB-137 Injection in Participants With Mild to Moderate Liver Dysfunction and Those With Normal Liver Function. AHB-137 injection - Chronic Hepatitis B | Phase 1 | Recruiting | Ausper Biopharma Co., Ltd. | 32 | 2026-07-09 | 2026-07-29 |
| Study of AHB-171 in Chronic Hepatitis B Participants AHB-171, Placebo matching [Investigational Product], Nucleos(t)ide Analogue (NA) - Hepatitis B, Chronic | Phase 1 | Not yet recruiting | AusperBio Therapeutics Inc. | 144 | 2026-07-06 | 2026-06-01 |
| A Phase I Clinical Trial of CPU-YL01 Injection in Patients With Chronic Hepatitis B. CPU-YL01 Injection Intramuscular administration, Placebo intramuscular injection - Chronic Hepatitis B | Phase 1 | Enrolling by invitation | Jiangsu Chuangyuan Life Science and Technology Co., Ltd. | 74 | 2026-07-03 | 2026-11-05 |
| Study of the Pharmacokinetics and Safety of Glecaprevir/Pibrentasvir Initiated in Pregnancy in Women With Hepatitis C With and Without HIV Glecaprevir/pibrentasvir - Hepatitis C | Phase 1 / Phase 2 | Recruiting | National Institute of Allergy and Infectious Diseases (NIAID) | 30 | 2026-06-25 | 2026-08-14 |
| Safety and Antiviral Activity of a Monoclonal Hepatitis B Antibody: a Phase 1b, Open-label Trial in Individuals With Chronic Hepatitis D Infection HepB mAb19 - Hepatitis D, Chronic, Hepatitis B Chronic Infection | Phase 1 | Recruiting | Aarhus University Hospital | 15 | 2026-04-23 | 2026-05-28 |
| A Phase I Clinical Study of AHB - 171 in Healthy Participants(HP) and Chronic Hepatitis B (CHB) Participants AHB-171 Injection, Placebo, Nucleos(t)ide Analogue (NA) - Chronic Hepatitis B Infection | Phase 1 | Recruiting | Ausper Biopharma Co., Ltd. | 110 | 2026-04-13 | 2026-07-21 |
| Single Dose Study to Evaluate the Pharmacokinetics, Safety and Tolerability of Pevifoscorvir Sodium (ALG-000184) in Participants With Renal Impairment and in Healthy Participants With Normal Renal Function Pevifoscorvir Sodium (ALG-000184) - Chronic Hepatitis B Infection | Phase 1 | Completed | Aligos Therapeutics | 12 | 2026-03-10 | 2026-08-21 |
| A Randomised Controlled Phase 1 Study of Vaccine Therapy for Control or Cure of Chronic Hepatitis B Virus Infection Therapeutic hepatitis B vaccine, Commercial Hepatitis B vaccine - Chronic Hepatitis b | Phase 1 / Phase 2 | Not yet recruiting | Vaxine Pty Ltd | 40 | 2026-03-01 | 2025-09-22 |
| A Study on IB-001 Dose Response and Tolerability in Healthy Adults and Those With Chronic Hepatitis B IB-001, Placebo, Peginterferon Alfa-2A - Chronic Hepatitis B Virus Infection | Phase 1 | Recruiting | IntegerBio | 88 | 2026-02-20 | 2026-09-28 |
| A Phase 1/2, Open-Label, Single and Multiple Ascending Dose Study of CRMA-1001 in Adults With Chronic Hepatitis B CRMA-1001 - Chronic Hepaititis B | Phase 1 / Phase 2 | Recruiting | nChroma Bio | 66 | 2025-12-22 | 2026-06-15 |
Showing 20 of 592. Sign in to see all of them.
Hepatitis C (266) · Hepatitis B, Chronic (146) · Hepatitis B (106) · Hepatitis C, Chronic (105) · Liver Diseases (18) · HIV Infections (14) · Hepatitis, Chronic (14) · Virus Diseases (13) · Infections (11) · Acquired Immunodeficiency Syndrome (10) · Bronchiolitis Obliterans Syndrome (9) · Hepatitis, Autoimmune (8) · Fibrosis (7) · Carcinoma, Hepatocellular (6)
Digestive System Diseases (590) · Liver Diseases (574) · Infections (559) · Blood-Borne Infections (558) · Hepatitis, Viral, Human (558) · Virus Diseases (556) · Communicable Diseases (554) · RNA Virus Infections (355) · Flaviviridae Infections (336) · Pathological Conditions, Signs and Symptoms (286) · Pathologic Processes (285) · Disease Attributes (272) · Chronic Disease (265) · Hepatitis, Chronic (257)
Ribavirin (29) · Simeprevir (26) · entecavir (22) · peginterferon alfa-2a (22) · Ritonavir (21) · Tenofovir (21) · telaprevir (17) · 8-cyclohexyl-N-((dimethylamino)sulfonyl)-1,1a,2,12b-tetrahydro-11-methoxy-1a-((3-methyl-3,8-diazabicyclo(3.2.1)oct-8-yl)carbonyl)cycloprop(d)indolo(2,1-a)(2)benzazepine-5-carboxamide (11) · daclatasvir (10) · asunaprevir (8) · peginterferon alfa-2b (7) · Hepatitis B Vaccines (6) · faldaprevir (6) · samatasvir (6) · ABT-072 (5)
Merck Sharp & Dohme LLC (42) · Bristol-Myers Squibb (29) · Tibotec Pharmaceuticals, Ireland (25) · GlaxoSmithKline (22) · Gilead Sciences (20) · Hoffmann-La Roche (17) · National Institute of Allergy and Infectious Diseases (NIAID) (13) · Abbott (11) · Assembly Biosciences (11) · Boehringer Ingelheim (11) · Sunshine Lake Pharma Co., Ltd. (11) · Vertex Pharmaceuticals Incorporated (10) · Alios Biopharma Inc. (8) · Pfizer (8) · Enanta Pharmaceuticals, Inc (7)
United States (198) · China (79) · New Zealand (66) · United Kingdom (42) · South Korea (41) · Hong Kong (35) · Australia (32) · Germany (32) · Taiwan (30) · Belgium (29) · France (27) · Canada (23) · Puerto Rico (23) · Moldova (18) · Netherlands (18)
Yanhua Ding, Doctor (7) · Daniel Cohen, MD (4)
PMID 21488067, PMID 27257978, PMID 29703432, PMID 30625297, PMID 33317695, PMID 37290591, PMID 42550463, PMID 1538192, PMID 15577929, PMID 16310901, PMID 16375711, PMID 19852962, PMID 20090916, PMID 20091678, PMID 20619382, PMID 20938912, PMID 20951424, PMID 21060109, PMID 21145839, PMID 21354234, PMID 21699798, PMID 21751289, PMID 21865319, PMID 22239508, PMID 22414766, PMID 22425702, PMID 22981147, PMID 23070151, PMID 23183437, PMID 23190247, PMID 23396509, PMID 23490393, PMID 23717490, PMID 23747481, PMID 23774433, PMID 23856771, PMID 23872824, PMID 23877691, PMID 23877706, PMID 23941866, PMID 23979733, PMID 23982366, PMID 24041792, PMID 24097843, PMID 24145880, PMID 24148552, PMID 24295986, PMID 24394187, PMID 24434503, PMID 24555998
2009 (9), 2015 (6), 2014 (4), 2017 (4), 2008 (3), 2016 (3), 2019 (3), 2025 (3), 2023 (2), 2018 (1), N01CN00042 (1), P01AI055793 (1), P30CA015083 (1), R01AI049141 (1), R01AI065256 (1)