30 completed, 15 recruiting, 4 active not recruiting, 4 not yet recruiting. 51 Not applicable, 1 Phase 2, 1 Phase 3, 1 Phase 4.
Follow Heat Stress: new trials by email Literature Review of Heat Stress trials Research Report on Heat Stress
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Progressive Heat Exposure and Physiological Strain Constant Heat Exposure, Progressively Increasing Heat Exposure - Body Temperature Changes, Heat Stress | Not applicable | Recruiting | University of Ottawa | 14 | 2026-10-22 | 2026-11-12 |
| Indoor Overheating and Physiological Strain in Older Adults With COPD Simulated indoor thermal environment - Chronic Obstructive Pulmonary Disease (COPD), Heat Stress | Not applicable | Not yet recruiting | University of Ottawa | 18 | 2026-10-13 | 2026-10-05 |
| Efficacy of Electric Fans in Children During Heat Waves Simulated exposure to indoor overheating without fans, Simulated exposure to indoor overheating with fans - Heat Stress, Physiological Stress | Not applicable | Recruiting | University of Ottawa | 60 | 2026-10-02 | 2026-11-10 |
| Heat and Mental Health - PART 2 Heat/Humidity Exposure Condition, Thermoneutral Condition - Depressed Mood, Young Adults | Not applicable | Recruiting | Hartford Hospital | 75 | 2026-10-01 | 2026-10-29 |
| Exercise Intensity and Heat Responses in Children and Youth Low-Intensity Exercise in the Heat, Moderate-Intensity Exercise in the Heat, Vigorous-Intensity Exercise in the Heat - Body Temperature Changes, Heat Stress | Not applicable | Enrolling by invitation | University of Ottawa | 12 | 2026-07-21 | 2026-11-10 |
| Ambient Temperature and Thermoregulation During Exercise in Children and Youth Exercise at 22°C, Exercise at 26°C, Exercise at 31°C - Body Temperature Changes, Heat Stress | Not applicable | Recruiting | University of Ottawa | 12 | 2026-07-19 | 2026-11-10 |
| Consecutive Occupational Heat Exposure With and Without Overnight Cooling Simulated occupational heat exposure with recovery at recommended indoor temperature limit, Simulated occupational heat exposure with recovery in an overheated indoor environment - Body Temperature Changes, Heat Stress | Not applicable | Recruiting | University of Ottawa | 10 | 2026-06-24 | 2026-10-05 |
| Working in the Heat at Simulated Altitude: Effects of Normobaric Hypoxia on Physiological Strain Simulated Occupational heat exposure under normoxic conditions, Simulated Occupational heat exposure under hypoxic conditions - Body Temperature Changes, Heat Stress | Not applicable | Recruiting | University of Ottawa | 20 | 2026-06-17 | 2026-11-12 |
| Carbohydrate or Protein Drinks Before Exercise in the Heat Protein shake, Carbohydrate shake - Heat Stress, Diet Induced Thermogenesis | Not applicable | Not yet recruiting | Providence College | 16 | 2026-06-04 | 2026-06-15 |
| Efficacy and Safety of Modified ORS(Amr and Khulood ORS) in Diabetic Pilgrims During Hajj Modified Oral Rehydration Salts (ORS)( Amr and khulood ORS), Standard Oral Rehydration Salts (ORS) - Diabetes Mellitus, Heat Stress | Not applicable | Not yet recruiting | Amr kamel khalil Ahmed | 200 | 2026-06-01 | 2026-06-01 |
| Indigenous Nutritional Supplements for Pregnancy to Improve Resilience in Environmental Heat Indigenous Balanced Diet Arm - Heat Stress, Pregnancy | Not applicable | Not yet recruiting | Aga Khan University | 292 | 2026-03-01 | 2026-03-24 |
| Effects of Hot Baths Prior or After a Damaging Protocol on Muscle Function and HSP70 Expression Immersion, NIRS, isokinetic dynamometer - Recovery, Mechanical Stress | Not applicable | Recruiting | Centre Hospitalier Universitaire, Amiens | 96 | 2026-02-16 | 2026-04-30 |
| Heat Stress in Individuals With Schizophrenia Simulated exposure to indoor overheating - Heat Stress, Physiological Stress | Not applicable | Recruiting | University of Ottawa | 10 | 2025-11-08 | 2026-04-23 |
| Impact of Indoor Overheating on Physiological Strain in Children Simulated exposure to indoor overheating - Heat Stress, Physiological Stress | Not applicable | Active not recruiting | University of Ottawa | 10 | 2025-11-08 | 2026-11-12 |
| Suitability of a 26 °C Indoor Environment for Mitigating Heat Strain in Young Adults Simulated indoor temperature upper limit - Heat Stress, Physiological Stress | Not applicable | Recruiting | University of Ottawa | 10 | 2025-11-07 | 2026-06-16 |
| Title: ICARUS - Psycho-physiological Profiling of Low and High Heat-resilient Individuals Controlled Heat and Ultraviolet Radiation Exposure Protocol - Skin Cancer, Heat Tolerance | Not applicable | Recruiting | University of Thessaly | 80 | 2025-11-01 | 2026-04-03 |
| Suitability of the 26 °C Indoor Temperature Upper Limit for Older Adults: Impacts of Clothing and Daily Activity Simulated indoor temperature upper limit - Heat Stress, Physiological Stress | Not applicable | Active not recruiting | University of Ottawa | 10 | 2025-09-23 | 2026-11-12 |
| Identifying the Limits of Survivability in Heat-exposed Older Females Humidity-Ramp Protocol, Above-inflection fixed-condition exposure (5%), Below-inflection fixed-condition exposure (5%) - Heat Stress, Temperature Change, Body | Not applicable | Completed | University of Ottawa | 12 | 2025-07-16 | 2026-06-11 |
| The Impact of Wearing the Hijab on Whole-body Heat Loss During Exercise-heat Stress Exercise-heat stress with no hijab, Exercise-heat stress with a hijab - Heat Stress, Temperature Change, Body | Not applicable | Recruiting | University of Ottawa | 12 | 2025-06-13 | 2026-06-16 |
| Beat the Heat Boston Air Conditioner, Electricity subsidy - Hot Weather; Adverse Effect, Heat Effect | Not applicable | Recruiting | Harvard School of Public Health (HSPH) | 100 | 2025-05-19 | 2026-01-22 |
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Heat Stress Disorders (57) · Hyperthermia (18) · Motor Activity (13) · Body Temperature Changes (11) · Occupational Stress (4) · Fatigue (3) · Dehydration (2) · Heat Exhaustion (2) · Psychological Well-Being (2) · Alcohol Drinking (1) · Altitude Sickness (1) · Athletic Injuries (1) · Back Injuries (1) · Behavior (1) · Cognitive Dysfunction (1)
Wounds and Injuries (57) · Pathological Conditions, Signs and Symptoms (30) · Signs and Symptoms (27) · Behavior (14) · Body Temperature Changes (13) · Behavioral Symptoms (5) · Mental Disorders (4) · Occupational Diseases (4) · Stress, Psychological (4) · Metabolic Diseases (3) · Nutritional and Metabolic Diseases (3) · Pathologic Processes (3) · Cardiovascular Diseases (2) · Nervous System Diseases (2) · Neurocognitive Disorders (2)
Dietary Supplements (1) · Educational Status (1) · Ethanol (1) · Exercise (1) · Immersion (1) · Lacteol (1) · Physical Exertion (1) · Probiotics (1) · Radiation (1) · Salvage Therapy (1) · Steam Bath (1)
University of Ottawa (26) · University of Connecticut (2) · University of Texas Southwestern Medical Center (2) · Aga Khan University (1) · Amr kamel khalil Ahmed (1) · BRAC University (1) · Centre Hospitalier Universitaire, Amiens (1) · Direction Centrale du Service de Santé des Armées (1) · ETH Zurich (1) · Göteborg University (1) · Hartford Hospital (1) · Harvard School of Public Health (HSPH) (1) · Israeli Air Force Aeromedical Center (1) · Lakehead University (1) · Louisiana State University Health Sciences Center Shreveport (1)
Canada (27) · United States (9) · Switzerland (3) · Bangladesh (2) · Denmark (2) · France (2) · Greece (2) · Pakistan (2) · Austria (1) · Finland (1) · Indonesia (1) · Saudi Arabia (1) · Sweden (1) · United Kingdom (1)
Glen P Kenny, PhD (16) · Ronald J Sigal, MD, MPH (5) · Douglas J Casa, PhD (2) · Robert D Meade, PhD (2) · Andreas D Flouris, PhD (1) · Andreas Flouris (1) · Claudio Perret, PD Dr. (1) · Craig Crandall, PhD (1) · Erin McCallister, DPT (1) · Glen Kenny, PhD (1) · Glen P Kenny, PhD. (1) · Guy Plasqui (1) · Hannah Pallubinsky, Dr. (1) · Jari A Laukkanen, PhD (1)
PMID 30668567, PMID 39820413, PMID 40020224, PMID 40036754, PMID 40542541, PMID 40554659, PMID 41014079, PMID 41297035, PMID 41512819, PMID 41549363, PMID 41833559, PMID 42091206, PMID 42406578, PMID 42815509
P20TW013028 (1), R01AG069005 (1), R01ES035910 (1)